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本项目服务期截至2017年12月31日,请合理安排学习时间

美国风湿病学会(ACR)和美国风湿病卫生专业人员协会(ARHP)主办的2016年ACR/ARHP年会于11月11日-16日在美国Walter E华盛顿会议中心召开。世界各地的专家、学者共约16700参加了此次盛会,大会以风湿免疫病的发病机制、预防与治疗为主题,展开行业规范及前沿最高水平的学术交流。
本课程由西安杨森制药有限公司学术赞助,本次大会前沿课程由爱唯医学网(Elseviermed.cn)精选。所有课程可在ipad、iphone及大部分Android终端播放。方便您随时学习风湿病领域的最新研究进展。

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The Great Debate: To Taper or Not to Taper? - Biologic DMARDS in Low Rheumatoid Arthritis Disease Activity

The Great Debate: To Taper or Not to Taper? - Biologic DMARDS in Low Rheumatoid Arthritis Disease Activity
超级辩论——达到低疾病活动度的类风湿关节炎患者生物DMARDS是否应减停量?

Rheumatoid Arthritis – Clinical Aspects I: Pre-RA and Progression to Rheumatoid Arthritis

The Prognostic Value of Different Auto-Antibodies for Arthritis Development in Patients with Clinically Suspect Arthralgia
不同自身抗体对临床疑诊关节痛患者关节炎发展的预后价值

Dominant B-Cell Receptor Clones in Peripheral Blood Predict Onset of Arthritis in Individuals at Risk for Rheumatoid Arthritis
RA风险人群的外周血显性B细胞受体克隆可预测关节炎发病

Evaluation of 14-3-3η as a Tool for Diagnosis of Early RA in the EIRA
在EIRA队列中评估14-3-3η作为早期RA诊断工具的效果

Functional Disability in Patients Presenting with Clinically Suspect Arthralgia
临床疑似关节痛患者的功能障碍

Estimation of the Risk of Developing Rheumatoid Arthritis in High-Risk Subjects: Systematic Review and Meta-Analysis
高危患者进展为RA的风险评估:系统性综述和Meta分析

Stressful Life Events: A Trigger for Rheumatoid Arthritis Onset within a Year: A Case-Control Study
应激生活事件:一年内RA发病的诱因 一项病例对照研究

Spondylarthropathies and Psoriatic Arthritis – Clinical Aspects and Treatment II: Axial Spondyloarthritis – Treatment

Abatacept in the Treatment of Active Psoriatic Arthritis: 24-Week Results from a Phase III Study
阿巴西普用于治疗活动性银屑病性关节炎:一项为期24周的Ⅲ期研究结果

Four Year Imaging Outcomes in Patients with Axial Spondyloarthritis Treated with Certolizumab Pegol, Including Patients with Ankylosing Spondylitis and Non-Radiographic Axial Spondyloarthritis
中轴型脊柱关节炎患者采用赛妥珠单抗治疗的4年影像学结果,包括强直性脊柱炎和无放射学改变中轴型脊柱关节炎患者

Safety and Efficacy of Intravenous Golimumab in Adult Patients with Active Ankylosing Spondylitis: Results through Week 28
成人活动性强直性脊柱炎患者静脉注射戈利木单抗的安全性和有效性:一项28周研究结果

Treatment with Tofacitinib Is Associated with Clinically Meaningful Reductions in Axial MRI Inflammation in Patients with Ankylosing Spondylitis
托法替尼治疗强直性脊柱炎可显著降低患者脊柱MRI炎症

Update ASAS-EULAR Management Recommendations 2016
2016 ASAS/EULAR指南更新

Biologic Therapy: Prescription, Prior Authorization and Beyond

Biologics and Small Molecule Therapy: Intro To Specialty Pharmacy
生物疗法与小分子疗法:专业药房介绍

Biologics and Small Molecule Therapy: The Patient’s Journey
生物制剂及小分子药物治疗:患者旅程

Perioperative Management of Anti-rheumatic Medication in Patients with Rheumatic Diseases Undergoing Elective Total Hip or Knee Arthroplasty: A New ACR/AAHKS Clinical Guideline

ACR-AAHKS Guideline for the Perioperative Management of Anti-rheumatic Medications in Patients with Rheumatic Diseases Undergoing Elective Total Hip or Knee Arthroplasty DRAFT Recommendations
接受择期全髋关节或全膝关节置换术的风湿性疾病患者围术期抗风湿药物管理ACR-AAHKS指南推荐初稿

Moving from Evidence to Recommendations ACR-AAHKS Guideline for the Perioperative Management of Anti-rheumatic Medications in Patients with Rheumatic Diseases Undergoing Elective Total Hip or Knee Arthroplasty DRAFT Recommendations
从证据到推荐接受择期全髋关节或全膝关节置换术的风湿性疾病患者围术期抗风湿药物管理ACR-AAHKS指南推荐初稿

Imaging of Rheumatic Diseases II: Ultrasound in Rheumatoid Arthritis

Intramuscular Versus Ultrasound Guided Peritendinous Glucocorticoid Injection for Tenosynovitis in Patients with Rheumatoid Arthritis – A Randomized, Double-Blind, Controlled Study
类风湿关节炎患者肌肉注射或超声引导下腱鞘内注射糖皮质激素治疗腱鞘炎的比较——一项随机、双盲、对照研究

Is Ultrasound of the Hands Enough to Reveal Ongoing Subclinical Inflammation in Rheumatoid Arthritis Patients in Clinical Remission According to Composite Scores?
对于依据复合评分达到临床缓解的类风湿关节炎患者,手部超声的结果是否足以显示他们持续存在的亚临床炎症

Severity and Improvement of Morning Stiffness Independently Associate with Tenosynovitis in Patients with Rheumatoid Arthritis
类风湿关节炎患者晨僵的严重程度及其改善与腱鞘炎独立相关

Ultrasound Inflammation in Patients Presenting with Arthralgia Is Associated with Developing Arthritis
关节痛患者的超声炎症与关节炎进展之间存在相关性

Impact of Ultrasound in Treatment Decision of Rheumatoid Arthritis Assessed in Routine Clinical Practice
超声对常规临床实践中类风湿关节炎治疗决策的影响

Differential Pattern of Doppler Signals at Lower Extremity Entheses of Healthy Children
健康儿童下肢附着点多普勒信号的不同模式

Rheumatoid Arthritis – Clinical Aspects II: Risk and Impact of Comorbidity

Increased Risk of Cardiovascular Events in Patients with Rheumatoid Arthritis over a 15 Year Time Period
类风湿关节炎患者随访15年后心血管事件风险增加

Risk of Incident Diabetes Mellitus and Its Association with Disease-Modifying Antirheumatic Drugs and Statins in Rheumatoid Arthritis
类风湿关节炎患者的糖尿病发生风险及其与缓解病情抗风湿药物之间的相关性

Rheumatoid Arthritis Is an Independent Risk Factor for Increased Insulin Resistance and Impaired Beta-Cell Function: Impact of Disease Activity
类风湿关节炎是胰岛素抵抗增强和beta细胞功能障碍的独立风险因素:疾病活动度的影响

The Risk of Stroke in Patients with Rheumatoid Arthritis and the Association with Competing Adverse Events
类风湿关节炎患者的脑卒中风险及其与不良事件的相关性

Associations of Chronic Lung Comorbidity with Medications, Disease Activity, and All-Cause Mortality in Rheumatoid Arthritis
类风湿关节炎患者中慢性肺部疾病共病与治疗药物、疾病活动度和全因死亡率之间的相关性

Smoking Is Associated with Unfavorable Flare/Remission Pattern in Patients with Rheumatoid Arthritis
吸烟与类风湿关节炎患者不良的发作/缓解模式相关

Rheumatoid Arthritis – Small Molecules, Biologics and Gene Therapy II: Safety and Cost Effectiveness

Non-Medical Switch from Originator to Biosimilar Infliximab in Patients with Inflammatory Arthritis – Impact on s-Infliximab and Antidrug-Antibodies. Results from the Danish Rheumatologic Biobank and the Danbio Registry
炎症性关节炎患者从英夫利西单抗原研药到仿制药的非医疗转换对血清英夫利西单抗水平和抗药抗体的影响。来自丹麦风湿病生物库和DANBIO注册库的结果

Long-Term Registry Data in 4498 Patients with Rheumatoid Arthritis Indicate a Similar Safety but a Different Drug Retention Between Abatacept, Rituximab, and Tocilizumab
4498例类风湿关节炎患者的长期登记数据表明阿巴西普、利妥昔单抗和托珠单抗安全性相似,但药物持续使用情况存在差异

Claims-Based Analysis of Cost-Effectiveness Among Patients with Rheumatoid Arthritis Who Switched from a Tumor Necrosis Factor Inhibitor to Another Targeted Disease-Modifying Antirheumatic Drug
基于理赔对类风湿关节炎患者从肿瘤坏死因子抑制剂转换为其他缓解病情抗风湿药物的成本效益分析

Incidence of Cancer in Patients with Rheumatoid Arthritis and a History of Cancer Treated with Rituximab or Abatacept
有癌症病史的RA患者经利妥西单抗或阿巴西普治疗后的癌症发生率

Perioperative Use of DMARDs And/or TNF Inhibitors in Rheumatoid Arthritis
类风湿关节炎患者围手术期使用DMARDs和/或TNF抑制剂治疗

Spondylarthropathies and Psoriatic Arthritis – Clinical Aspects and Treatment III: Axial Spondyloarthritis – Clinical

Defining the Spectrum of Axial Spondyloarthritis in Members of Patients with Ankylosing Spondylitis
强直性脊柱炎患者家庭成员的中轴型脊椎关节炎谱

Validation of the ASAS Health Index: Results of a Multicenter International Study in 23 Countries
验证ASAS健康指数:一项在23个国家开展的多中心国际研究结果

Is Disease Activity Associated with Work Productivity Loss, Presenteeism, and Absenteeism in Patients with Early Axial Spondyloarthritis? Results from the Spondyloarthritis Caught Early (SPACE)-Cohort
疾病活动度是否与早期中轴型脊柱关节炎患者工作效率降低、出勤及缺勤存在相关性?SPACE队列研究的结果

Exploring the Window of Opportunity for Drug-Free Clinical Remission in Patients with Active, Very Early Peripheral Spondyloarthritis (CRESPA Trial)
探索极早期外周型脊柱关节炎活动期患者无药临床缓解的机会窗口

Tuberculosis risk in AS, PsA, and other SpA in Sweden
瑞典AS、PsA及其他SpA患者的结核病风险

Sensitivity and Specificity of Autoantibodies Against CD74 in Early Axial Spondyloarthritis
CD74自身抗体在早期中轴型脊柱关节炎中的敏感性和特异性

Rheumatoid Arthritis – Clinical Aspects III: Prevention of Comorbidity

Screening for and Management of Comorbidities after a Nurse-Led Program: Results of a 3 Year Longitudinal Study in 776 Established RA Patients
护士主导项目后合并症的筛查和管理:一项776例确诊RA患者的3年纵向研究结果

Risk Factors for Cardiovascular Disease Predate the Onset of Symptoms of Rheumatoid Arthritis
心血管疾病风险因素早于类风湿关节炎症状出现

Preoperative Timing of Infliximab and Risk of Post-Operative Infection in a Medicare Cohort
在一项医疗保险队列研究中评估英夫利西单抗术前干预时机和术后感染风险

Prosthetic Joint Infection with Staphylococcus Aureus: Recurrence after Surgical Treatment in U.S. Veterans with and without Rheumatoid Arthritis
人工关节金黄色葡萄球菌感染:美国退伍军人中伴或不伴类风湿关节炎患者的术后复发情况

Effect of Temporary Methotrexate Discontinuation on Efficacy of Seasonal Influenza Vaccination in Patients with Rheumatoid Arthritis: A Randomized Clinical Trial
类风湿关节炎患者暂停甲氨蝶呤治疗对季节性流感疫苗疗效的影响:一项随机临床试验

Myocardial Abnormalities Are Associated with Corrected QT Interval in Patients with Rheumatoid Arthritis without Cardiac Symptoms Assessed Using Cardiac Magnetic Resonance Imaging
心脏磁共振成像显示无心脏症状的类风湿关节炎患者中心肌异常与校正QT间期相关

Treatment of Rheumatoid Arthritis When the Patient is Not Well

Treatment of Rheumatoid Arthritis When the Patient Is Not Well
类风湿关节炎患者状况不佳时的治疗

Spondyloarthropathies: Advances in the Science and Management

Relevance of the Gut/Joint Axis for the Management of Spondyloarthritis in Daily Clinical Practice
日常临床实践中肠道/关节轴与脊柱关节炎患者管理的相关性

Current Guidelines for the Treatment of Ankylosing Spondylitis and Non-Radiographic Axial Spondyloarthropathies
强直性脊柱炎和放射学阴性中轴型脊柱关节炎治疗的现有指南

Emerging Therapies in Axial Spondyloarthritis (SpA)
中轴型脊柱关节炎新兴治疗

Rheumatoid Arthritis – Clinical Aspects IV: Managing Patients in Remission

Long-Term Outcomes after Disease Activity Guided Tapering of Tumor Necrosis Factor Inhibition in Rheumatoid Arthritis: 3 Year Data of a Randomised Controlled Pragmatic Non Inferiority Strategy Study
类风湿关节炎患者根据疾病活动度进行TNF抑制剂减量后的长期转归:一项随机对照、实用性非劣效性研究的3年数据

Predictors of Disease Control In Patients With RA After Stopping TNFi: Results From The DUTCH National POET Study
类风湿关节炎患者停用TNFi治疗后疾病控制的预测因素:荷兰POET研究结果

Dose Reduction or Discontinuation of Biological Therapy in Patients with Rheumatoid Arthritis in Remission – 1-Year Results of a Guideline-Directed Longitudinal Cohort Study
类风湿关节炎缓解期生物治疗减量或停药:一项指南指导的纵向队列研究(ADOPT研究)的1年结果

Dose Interval Prolongation of Adalimumab Based on Adalimumab Concentration in Rheumatoid Arthritis
类风湿关节炎患者基于阿达木单抗浓度延长给药间隔时间

The Good, the Bad, and the Ugly – Refractory Rheumatoid Arthritis in 2016
好消息、坏消息及不好的一面——2016年难治性类风湿关节炎领域进展

Validity of a 2-Component Disease Activity Score for Accurate Assessment of Synovitis in Rheumatoid Arthritis
2种要素的疾病活动度评分可精确评估类风湿关节炎患者滑膜炎

Rheumatoid Arthritis – Small Molecules, Biologics and Gene Therapy III: Small Molecules and Early Intervention

Lipid Profile and Effect of Statin Treatment in Pooled Phase 2 and Phase 3 Baricitinib Studies
巴瑞替尼2期和3期汇总研究的脂质谱分析和他汀类药物治疗疗效

Major Adverse Cardiovascular Events: Risk Factors in Patients with RA Treated with Tofacitinib
主要不良心血管事件:托法替尼治疗类风湿关节炎患者的风险因素

The Effect of Filgotinib (GLPG0634), an Oral JAK1 Selective Inhibitor on Patient-Reported Outcomes: Results from Two 24-Week Phase 2B Dose Ranging Studies
JAK1选择性口服抑制剂Filgotinib对患者报告结局的影响:两项为期24周的2B期剂量范围研究的结果

Efficacy and Safety of Low Dose and Short-term IL-2 Treatment in Patients receiving RA Therapy
接受类风湿关节炎治疗的患者应用低剂量短期IL-2治疗的有效性和安全性

Herpes Zoster in Patients with Moderate to Severe Rheumatoid Arthritis Treated with Baricitinib
巴瑞替尼治疗中至重度类风湿关节炎患者带状疱疹的发生情况

A Single Infusion of Rituximab Delays the Onset of Arthritis in Subjects at High Risk of Developing RA
类风湿关节炎高危患者单次输注利妥昔单抗可推迟关节炎发作

Rheumatoid Arthritis – Clinical Aspects V: Challenges in the Assessment and Management of Established RA

Utility of Patient-Reported Outcomes Measurement Information System (PROMIS) 29 Short Form for Understanding Interplay Between Patient-Reported Outcome Measures and Physician Driven Disease Activity Measures
利用患者报告结局测量信息系统(PROMIS)29简易量表探寻患者报告结局测量和医师主导的疾病活动度检测之间的相互作用

Impact of Mental Health on Indicators of Disease Severity Among Patients with Inflammatory Arthritis
炎症性关节炎患者的精神健康对疾病严重程度指标的影响

Do Depression and Anxiety Reduce the Chance of Remission in Rheumatoid Arthritis and Psoriatic Arthritis?
抑郁及焦虑是否降低炎症性关节炎的缓解机会?

Changing Patterns over Time in Opiate Use in U.S. Rheumatoid Arthritis Patients
阿片类药物在美国类风湿关节炎患者中用药模式的改变

Association of Weight Loss with Improved Disease Activity in Patients with Rheumatoid Arthritis
类风湿关节炎患者中体重减轻与疾病活动度改善的相关性

Predictors of Patient Decision to Discontinue Anti-Rheumatic Medication in Patients with Rheumatoid Arthritis: Results from the Ontario Best Practices Research Initiative
RA患者停用抗类风湿药物的预测因素:安大略最佳实践研究计划的结果

Rheumatoid Arthritis in Real Life: How Do You Treat to Target in 2016

When and How to Treat Preclinical or Very Early Rheumatoid Arthritis
何时以及如何治疗临床前或极早期类风湿关节炎

Implementation of Treat to Target in Rheumatoid Arthritis through a Learning Collaborative
通过学习合作的方式对类风湿关节炎患者施行目标治疗方案

Cardiovascular Outcomes in Rheumatoid Arthritis...the Evolution of Observation
类风湿关节炎患者的心血管预后 观察的“演变”

Rheumatoid Arthritis – Clinical Aspects VI: Management of Early Rheumatoid Arthritis

Early Use of Subcutaneous MTX Monotherapy vs. MTX Oral or Combination Therapy Significantly Delays Time to Initiating Biologics in Early RA
早期使用皮下注射MTX单药治疗较MTX口服或MTX联合治疗显著推迟早期RA患者起始生物制剂治疗的时间

The Initial Dose of Methotrexate per Weight Is Determinant of Disease Activity and Early DAS28 Remission in DMARD-Naive Early Rheumatoid Arthritis Patients Receiving Usual Care
在接受常规护理DMARD初治的早期类风湿关节炎患者中每千克体重的甲氨蝶呤初始剂量是疾病活动度和早期DAS28缓解的决定因素

The Diagnostic and Predictive Value of Anti- Acetylated Peptide Antibodies in RA Patients Starting Methotrexate Treatment
抗乙酰化肽抗体对起始甲氨蝶呤治疗RA患者的诊断和预测价值

Rheumatoid Arthritis (RA): Premature Use of Biologics Accelerating in United States (US)
类风湿关节炎(RA):生物制剂过早使用情况在美国愈演愈烈

Automated Cell Phone Monitoring of Disease Activity and Medication Adherence in Early Rheumatoid Arthritis
早期类风湿关节炎使用自动化手机监控疾病活动度和药物依从性

Assessing Bone Erosions in the Metatarsophalangeal Joints of Patients with Early Rheumatoid Arthritis: A Comparison Between MRI and Ultrasound
早期类风湿关节炎患者跖趾关节的骨侵蚀评估:MRI和超声比较

Spondylarthropathies and Psoriatic Arthritis – Clinical Aspects and Treatment V: Imaging of Spondyloarthritis

Zygapophyseal Joint Fusion in Ankylosing Spondylitis Assessed Using Computed Tomography: Associations with Syndesmophytes and Spinal Motion
使用计算机断层扫描成像评估强直性脊柱炎患者的关节突关节融合:骨赘和脊柱活动的相关性

Adding MRI of the Spine to the ASAS Classification Criteria for Axial Spondyloarthritis, Redundant or Beneficial? Results from the Spondyloarthritis Caught Early (SPACE)-Cohort
中轴型脊柱关节炎的ASAS分类标准中加入脊柱MRI多余还是有益?来自SPACE队列研究的结果

The Association Between Sonographic Enthesitis and Radiographic Damage in Psoriatic Arthritis
银屑病关节炎中超声附着点炎和放射学损伤之间的相关性

Scoring Syndesmophytes on CT Spine Images of Patients with Radiographic Axial Spondyloarthritis from the Sensitive Imaging of Axial Spondyloarthritis (SIAS) Cohort
放射学中轴型脊柱关节炎患者基于脊柱CT图像进行骨赘评分:来自SIAS队列研究的结果

Rheumatoid Arthritis – Clinical Aspects VII: The Impact of Treating to Target

Clinical and Radiological Outcomes of 5 Years’ Remission Steered Treatment in Early Rheumatoid and Undifferentiated Arthritis Patients
早期类风湿关节炎和未分化关节炎患者经缓解导向治疗的5年临床和放射学结局

10+ Years’ Follow-Up of a Danish 2-Year Treatto-Target RCT in Patients with Early Rheumatoid Arthritis: Baseline Predictors of Functional and Radiographic Outcomes
丹麦早期类风湿关节炎患者中开展的为期2年达标治疗RCT超过10年的随访结果:功能和放射学结局的基线预测因素

Early Radiological Progression in Rheumatoid Arthritis Leads to More Long-Term Joint Damage in Daily Clinical Practice; Six Year Radiological Outcomes of a Strict Treat-to-Target Cohort in the Netherlands
日常临床实践中类风湿关节炎的早期放射学进展将导致更长期的关节损伤;一项严格达标治疗队列的6年放射学随访结果

Does SDAI Remission Lead to Better 5-Year Outcomes Than SDAI Low Disease Activity?
SDAI缓解患者是否较SDAI低疾病活动度患者具有更好的5年结局?

Assessment of Two Different DAS Treatment Targets in Early Active Rheumatoid Arthritis Patients
早期活动性类风湿关节炎患者中评估两种不同DAS治疗目标

Implementation Of TTT In RA Through A Learning Collaborative:The TRACTION Trail
通过学习合作改进类风湿关节中达标治疗的执行

Rheumatoid Arthritis – Small Molecules, Biologics and Gene Therapy V: New Biologics and Remission Induction

Efficacy and Safety of Sarilumab Versus Adalimumab in a Phase 3, Randomized, Double-Blind, Monotherapy Study in Patients with Active Rheumatoid Arthritis with Intolerance or Inadequate Response to Methotrexate
3期随机双盲单药治疗研究比较Sarilumab和阿达木单抗在甲氨蝶呤不耐受或应答不足的活动期类风湿关节炎患者治疗中的有效性及安全性

Efficacy and Safety of Monotherapy with Sirukumab, an Anti–IL-6 Cytokine Monoclonal Antibody, Compared with Adalimumab Monotherapy in Biologic-Naive Patients with Active Rheumatoid Arthritis: Results of a Global, Randomized, Double-Blind, Parallel-Group, Phase 3 Study
在生物制剂初治的活动期类风湿关节炎患者中比较Sirukumab(抗IL-6单克隆抗体)单药治疗与阿达木单抗单药治疗的有效性及安全性:一项全球性随机双盲平行组3期研究的24周结果

Efficacy and Safety of Sirukumab, an Anti– IL-6 Cytokine Monoclonal Antibody, in Patients with Active Rheumatoid Arthritis Despite Anti-TNF Therapy: Results from a Randomized, Double-Blind, Placebo-Controlled, Global, Phase 3 Study
评估Sirukumab(抗IL-6细胞因子单克隆抗体)对既往接受抗TNF治疗的活动期类风湿关节炎患者的有效性和安全性:一项全球性随机双盲安慰剂对照3期研究的结果

Efficacy of Sirukumab, an Anti–IL-6 Cytokine Monoclonal Antibody, Based upon Prior Use of Non-Anti-TNF Biologics in Patients with Active Rheumatoid Arthritis Despite Anti-TNF Therapy: Results from a Global Phase 3 Study
在经抗TNF治疗的活动期类风湿关节炎患者中基于既往非抗TNF生物制剂的使用评估Sirukumab(抗IL-6细胞因子单克隆抗体)的有效性:一项全球性3期研究的结果

Dual Cytokine Inhibition with ABT-122, a Tnf– and IL-17–Targeted Dual Variable Domain Immunoglobulin (DVD-Ig™): Results from a 24-Week Open-Label Extension Study in Patients with Rheumatoid Arthritis
应用双重细胞因子抑制剂ABT-122同时靶向TNF和IL-17的双重可变结构域免疫球蛋白(DVD-Ig):一项为期24周在类风湿关节炎患者中开展的开放标签扩展性研究结果

Maintenance of Clinical Remission and Radiographic Non-Progression with MTX after Completion of 1 Year Initial Treatment with Certolizumab Pegol in Japanese Patients with Early Rheumatoid Arthritis
日本早期类风湿关节炎患者为期1年赛妥珠单抗治疗后应用MTX可维持临床缓解且影像学无进展

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