与注射受污染的类固醇产品相关的中枢神经系统(CNS)和脑膜旁感染的暂行治疗指南
This is interim guidance for treatment of adult patients with CNS infections (including meningitis1) and/or parameningeal infections associated with injections of contaminated steroid products from the New England Compounding Center. Interim guidance may change as new information becomes available.
These recommendations are based upon growing evidence that Exserohilum rostratum (a brown-black mold) is the predominant pathogen in this outbreak, and expert opinion and published literature indicating that voriconazole may be effective in treating infections due to brown-black molds as well as infections due to Aspergillus species. Recommendations are also based on considerations related to the anatomic site of infection and pharmacokinetics of antifungal agents. CDC continues to consult with national experts about treatment options for fungal CNS and parameningeal infections in patients associated with this outbreak.
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文章来源:MDC
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