硫化氢调节间充质干细胞及调节性T细胞的稳态

Hydrogen Sulfide Regulates Homeostasis of Mesenchymal Stem Cells and Regulatory T Cells
2017-01-03 16:40发表评论
作者:Yang, R., Liu, Y., Shi, S.
机构: 北京大学口腔医学院暨口腔医院口腔正畸科
期刊: J DENT RES2016年12月13期95卷

Hydrogen sulfide (H2S) has long been known as a toxic gas. However, recently accumulated evidence suggests that H2S contributes to a variety of physiologic and pathologic processes. Endogenous H2S production is regulated by multiple enzymes that are differentially expressed in the cardiovascular, neuronal, immune, renal, respiratory, gastrointestinal, reproductive, liver, and endocrine systems. Alteration of H2S metabolism may affect multiple signaling pathways and tissue homeostasis. The growing number of diverse targets for which H2S serves as a gasotransmitter has been extensively reviewed elsewhere. In this review, the authors discuss current emerging evidence that H2S regulates mesenchymal stem cell and T-cell functions. © International & American Associations for Dental Research 2016.

通讯机构:Department of Orthodontics, Peking University, School and Hospital of Stomatology, Beijing, China
学科代码:口腔医学   关键词:硫化氢 间充质干细胞 ,中国作者重要发表 爱思唯尔医学网, Elseviermed
来源: Scopus
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