Article Outline
- Abstract
- Patients and Methods
- Study Population
- Treatment
- Outcome Measures
- Masking to Treatment Assignment
- Statistical Analysis
- Results
- Patients and Treatment
- Change in Visual Acuity in Patients Treated with the Same Dosing Regimen for 2 Years
- Secondary Outcomes in Patients Treated with the Same Dosing Regimen for 2 Years
- Outcomes among Patients with Dosing Regimen Reassigned at 1 Year
- Adverse Events
- Discussion
- Supplementary data
- References
- Copyright
Objective
To describe effects of ranibizumab and bevacizumab when administered monthly or as needed for 2 years and to describe the impact of switching to as-needed treatment after 1 year of monthly treatment.
Design
Multicenter, randomized clinical t