Respiratory Physiology & Neurobiology
(RESP PHYSIOL NEUROBI) 《呼吸生理学与神经生物学》
2015年影响因子
1.773
期刊介绍
展开
推荐阅读
- 2013-03-15•发育中颈动脉体炎症与早产窒息的关系
- 2013-03-15•颈动脉化学感受器发育和新生儿窒息
- 2013-03-15•颈动脉体和胎儿和新生儿中唤醒
- 2013-03-15•围产期尼古丁/吸烟暴露和发育期颈动脉化学感受器
- 2013-03-15•经表观遗传机制通过新生期间断低氧氧感受发育编程
- 2013-03-15•长期高氧和颈动脉体发育
目录导读
Published 2013年3月,Volume 186,Issue 1
最新一期
|
Mechanism of augmented exercise hyperpnea in chronic heart failure and dead space loadingReview ArticlePages 114-130 Chi-Sang Poon, Chung Tin
Show preview |
Supplementary content | Related articles | Related reference work articles
|
|
||||
Research Articles
|
Spinal pathways mediating phrenic activation during high frequency spinal cord stimulationOriginal Research ArticlePages 1-6 Anthony F. DiMarco, Krzysztof E. Kowalski
Show preview | Related articles | Related reference work articles
|
|
||||
|
Evidence for rhombomeric organization of multiple respiratory oscillators in the bullfrog brainstemOriginal Research ArticlePages 7-15 Michael J. Klingler, Michael S. Hedrick
Show preview | Related articles | Related reference work articles
|
|
||||
Highlights
► We examine if multiple respiratory oscillators are present in brainstem rhombomeres. ► Respiratory oscillators are contained in several rhombomeres during development. ► Multiple oscillators are sufficient but not necessary for rhythm generation.
|
Time course of asymptomatic interstitial pulmonary oedema at high altitudeOriginal Research ArticlePages 16-21 Pierre Bouzat, Guillaume Walther, Thomas Rupp, Gregory Doucende, Jean-François Payen, Patrick Levy, Samuel Verges
Show preview | Related articles | Related reference work articles
|
|
||||
Highlights
► Interstitial pulmonary oedema was assessed at 4350 m by ultrasonography. ► Interstitial pulmonary oedema was clearly observed the first 2 days at altitude. ► Transient interstitial pulmonary oedema is part of acclimatization to high altitude. ► It does not relate to changes in left ventricle function or pulmonary hypertension.
|
Modeling of release position and ventilation effects on olfactory aerosol drug deliveryOriginal Research ArticlePages 22-32 Xiuhua A. Si, Jinxiang Xi, JongWon Kim, Yue Zhou, Hualiang Zhong
Show preview | Related articles | Related reference work articles
|
|
||||
Highlights
► Significantly improved olfactory dosages were achieved with proposed protocols. ► Drug release at front vestibule gives twice olfactory dosage than at back. ► Deep intubation with inhalation yields optimal olfactory depositions. ► Current delivery efficiencies are still too low to be clinically practical.
|
CO2 relaxation of the rat lung parenchymal stripOriginal Research ArticlePages 33-39 Michael J. Emery, Randy L. Eveland, Jin-Hye Min, Jacob Hildebrandt, Erik R. Swenson
Show preview | Related articles | Related reference work articles
|
|
||||
Highlights
► We investigated the CO2 effects on recoil in normoxic rat lung parenchymal strips. ► We also investigated the role of myosin in CO2-dependent parenchymal strip recoil. ► Increasing
(20–53 mmHg) produced reversible parenchymal relaxation. ► Myosin blocker, 2,3-BDM (30 mM) eliminated CO2-dependent parenchymal strip recoil. ► Non-smooth muscle myosin may underlie CO2-dependent parenchymal recoil.
|
Impact of laparoscopic surgery on thoracoabdominal mechanics and inspiratory muscular activityOriginal Research ArticlePages 40-44 Adriana Claudia Lunardi, Denise de Moraes Paisani, Clarice Tanaka, Celso Ricardo Fernandes Carvalho
Show preview | Related articles | Related reference work articles
|
|
||||
Highlights
► Laparoscopic surgery reduces chest wall ventilation and inspiratory muscular activity. ► Laparoscopic effects seem to depend on the patient's reported pain. ► This is the first study to identify changes in the chest wall mechanics induced by laparoscopic. ► OEP is a new technique that evaluates chest wall kinematics in surgical patients.
|
The in-vivo oxyhaemoglobin dissociation curve at sea level and high altitudeOriginal Research ArticlePages 45-52 Dahlia Y. Balaban, James Duffin, David Preiss, Alexandra Mardimae, Alex Vesely, Marat Slessarev, G.R. Zubieta-Calleja, Ernest R. Greene, David B. MacLeod, Joseph A. Fisher
Show preview |
Supplementary content | Related articles | Related reference work articles
|
|
||||
Highlights
► We describe the first in-vivo measurement of the O2 dissociation curves. ► High altitude residents have O2 dissociation curves that are shifted to the left. ► Blood pH was sufficient to account for the shift of the O2 dissociation curves. ► A mathematical model predicted the O2 dissociation curves from the subjects’ pH.
|
Regular exercise training attenuates pulmonary inflammatory responses to inhaled alumina refinery dust in miceOriginal Research ArticlePages 53-60 Valéria Marques Ferreira Normando, Flavia Mazzoli-Rocha, Dayse Kelly Molina Moreira, Bárbara Chaves Barcellos, Domingos Wanderley Picanço-Diniz, Walter Araújo Zin
Show preview | Related articles | Related reference work articles
|
|
||||
Highlights
► For the first time the interaction between exposure to alumina and exercise is addressed. ► In mice exposed to alumina the viscoelastic component of elastance and the viscoelastic/inhomogeneous pressure augmented. ► In the same animals the lung polymorphonuclear amount, the fraction area of alveolar collapse and TGF-β increased. ► Exercise may mitigate the pro-inflammatory response to inhaled aluminum refinery dust.
|
Improvement of exercise capacity in monocrotaline-induced pulmonary hypertension by the phosphodiesterase-5 inhibitor VardenafilOriginal Research ArticlePages 61-64 Stephan Schroll, Daniela Sebah, Michael Wagner, Viktoria Popara, Michael Pfeifer, Friedrich Blumberg
Show preview | Related articles | Related reference work articles
|
|
||||
Highlights
► The effects of the phosphodiesterase-5 inhibitor Vardenafil in pulmonary arterial hypertension are unknown. ► We show for the first time that Vardenafil attenuates monocrotaline-induced pulmonary artery hypertension in rats. ► Vardenafil improves pulmonary vascular remodeling, hemodynamics, right ventricular hypertrophy and exercise capacity. ► Whether Vardenafil is a treatment option for patients with pulmonary hypertension needs to be elucidated.
|
Early and late acute lung injury and their association with distal organ damage in murine malariaOriginal Research ArticlePages 65-72 Mariana C. Souza, Johnatas D. Silva, Tatiana A. Pádua, Vera Luiza Capelozzi, Patricia R.M. Rocco, Maria das Graças Henriques
Show preview | Related articles | Related reference work articles
|
|
||||
Highlights
► Acute lung injury was developed earlier than cerebral malaria symptoms. ► At day 1, lung presents areas with alveolar collapse, neutrophil infiltration, interstitial oedema and mechanics impairment. ► At late phase, cerebral malaria symptoms were associated with distal organ damage and an increase in inflammatory cytokines.
|
Influence of age, body temperature, GABAA receptor inhibition and caffeine on the Hering–Breuer inflation reflex in unanesthetized rat pupsOriginal Research ArticlePages 73-80 Ashley V. Arnal, Julie L. Gore, Alison Rudkin, Donald Bartlett Jr., J.C. Leiter
Show preview | Related articles | Related reference work articles
|
|
||||
Highlights
► Caffeine blunted thermal prolongation of the Hering–Breuer Reflex. ► Caffeine probably achieved this effect by blocking adenosine A2a receptors. ► Blocking GABAA receptors had no effect on the thermal prolongation of the Hering–Breuer Reflex.
|
Differences in gas exchange between severities of chronic obstructive pulmonary diseaseOriginal Research ArticlePages 81-86 Wilawan Thirapatarapong, Hilary F. Armstrong, Byron M. Thomashow, Matthew N. Bartels
Show preview | Related articles | Related reference work articles
|
|
||||
Highlights
► The chief finding of this study is that there is altered gas exchange with exercise, as measured by
and 
, between patients with various severities of COPD. ► Patients with GOLD 3 and 4 COPD have a significantly higher 
and lower 
at peak exercise than GOLD 2 patients. ► We speculate that true physiology with exercise includes both lower 
and higher 
in GOLD 2 COPD, reflecting less efficient ventilation, and high 
and low 
in GOLD 3 and 4 COPD, reflecting ventilatory limitations. ► Our novel finding is that we demonstrate ventilatory changes over the spectrum of advanced COPD with complete ventilatory parameters on CPET.
|
Uncoupling mitochondrial activity maintains body Original Research Article |
|
||||
during hemorrhage-induced O2 deficit in the anesthetized ratHighlights
► Oxygen consumption decreases in a model of acute hemorrhage in the rat when O2 delivery decreases, just like in larger mammal. ► Increasing O2 demand during hemorrhage induced O2 deficit increases oxygen consumption and O2 delivery. ► Cellular and systemic mechanisms which decreases O2 demand during hemorrhage account for a large part of HS induced
decline.
|
Effects of unsupported arm training on arm exercise-related perception in COPD patientsOriginal Research ArticlePages 95-102 I. Romagnoli, G. Scano, B. Binazzi, C. Coli, G. Innocenti Bruni, L. Stendardi, F. Gigliotti
Show preview |
Supplementary content | Related articles | Related reference work articles
|
|
||||
Highlights
► The impact of upper extremity training on UAE dyspnea and arm fatigue remains unclear. ► Arm training might affect unsupported arm exercise-related perception by decreasing motor output to respiratory muscles. ► UAET improved outcome measurements without affecting chest wall operational volumes or configuration. ► A reduction in ventilation correlated with a simultaneoreduction in chemical output. ► A decrease in ventilatory demand relative to decreased central motor output accounted for a decrease in arm and respiratory effort in UAET.
|
The rise in carboxyhemoglobin from repeated pulmonary diffusing capacity testsOriginal Research ArticlePages 103-108 Gerald S. Zavorsky
Show preview | Related articles | Related reference work articles
|
|
||||
Highlights
► Repeated 5-s single breath-hold diffusing capacity tests were performed. ► 55 ppm NO and 0.28% CO, 19.5% O2, 9.5% He, Bal N2, was inhaled per test. ► Carboxyhemoglobin percentage increased by 0.44% per test between the second and 22nd test. ► Pulmonary diffusing capacity for CO was significantly reduced when carboxyhemoglobin percentage was 6% (the 10th test). ► Pulmonary diffusing capacity for NO was not altered after 22 tests while methemoglobin percentage only changed minimally.
|
Laryngeal reflex apnea in neonates: Effects of CO2 and the complex influence of hypoxiaOriginal Research ArticlePages 109-113 L. Xia, J.C. Leiter, D. Bartlett Jr.
Show preview | Related articles | Related reference work articles
|
|
||||
Highlights
► We measured the laryngeal chemoreflex (LCR) in decerebrate neonatal piglets. ► LCR-induced apnea (LCR-A) was prolonged by hypocapnia and shortened by hypercapnia. ► In hypoxia some piglets had biphasic responses of respiratory frequency and LCR-A. ► Prolonged LCR-A in hypoxia may be a trigger for the Sudden Infant Death Syndrome.
发表评论网友评论(0)
京公网安备 11010102000271号