手术类型不影响年轻早期乳腺癌患者的总生存率
作者对6项比较保乳手术(BCS)联合全乳房放射治疗(WBRT)与乳房切除术总生存率的研究进行了meta分析,共纳入22598名早期年轻(≤40 岁)乳腺癌患者。不同治疗组间的死亡风险并无显著差异。
作者总结称, 与BCS联合WBRT相比,乳房切除术并不能提高年轻早期乳腺癌患者的总生存率。
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The authors performed a meta-analysis of six studies comparing overall survival between breast-conserving surgery (BCS) plus whole breast radiotherapy (WBRT) and mastectomy in 22,598 young (≤40 years) patients with early-stage breast cancer. Risk for death was not different between treatment groups.
The authors conclude that mastectomy does not result in superior overall survival compared with BCS plus WBRT in young patients with early breast cancer.
The Breast
Overall Survival According To Type of Surgery in Young (≤40 Years) Early Breast Cancer Patients: A Systematic Meta-Analysis Comparing Breast-Conserving Surgery Versus Mastectomy
Breast 2015 Feb 23;[EPub Ahead of Print], J Vila, S Gandini, O Gentilini
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