By Marc C. Hochberg, MD, MPH, Professor of Medicine, Head, Division of Rheumatology and Clinical Immunology, University of Maryland School of Medicine, Baltimore, MD, USA; Alan J. Silman, MD, ARC Professor of Rheumatic Disease Epidemiology, Director, ARC Epidemiology Research Unit, University of Manchester, UK; Josef S. Smolen, MD, Department of Internal Medicine, University of Vienna and Center for Rheumatic Diseases, Lainz Hospital, Vienna, Austria; Michael E. Weinblatt, MD, Professor of Medicine, Harvard Medical School, Co-Director of Clinical Rheumatology, Brigham and Women's Hospital, Boston, MA and Michael H. Weisman, MD, Director, Division of Rheumatology, Cedars-Sinai Medical Center; Professor of Medicine, University of California at Los Angeles Medical Center, Los Angeles, CA, USA