Hearing Research
(HEARING RES) 《听力研究》
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目录导读
Published 2012年10月,Volume 292,Issue 1-2
最新一期
Research Papers
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Characterizing the dependence of pure-tone frequency difference limens on frequency, duration, and levelOriginal Research ArticlePages 1-13 Christophe Micheyl, Li Xiao, Andrew J. Oxenham
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Immunogold TEM of otoconin 90 and otolin – relevance to mineralization of otoconia, and pathogenesis of benign positional vertigoOriginal Research ArticlePages 14-25 Leonardo R. Andrade, Ulysses Lins, Marcos Farina, Bechara Kachar, Ruediger Thalmann
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Highlights
► Immunogold TEM (ITEM) allows ultrastructural localization of OC90 in otoconia. ► Alignment of OC90 gold particles indicates attachment of OC90 to collagenous otolin. ► ITEM indicates that fibrils interconnecting otoconia consist of otolin. ► In two-year-old mice demineralization causes detachment of otoconia from each other. ► We postulate that in humans an analogous detachment of otoconia results in BPV
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Distortion products and their influence on representation of pitch-relevant information in the human brainstem for unresolved harmonic complex tonesOriginal Research ArticlePages 26-34 Christopher J. Smalt, Ananthanarayan Krishnan, Gavin M. Bidelman, Saradha Ananthakrishnan, Jackson T. Gandour
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Highlights
► Envelope and spectral FFRs preserve pitch relevant information. ► Distortion product magnitude decreases with increasing masker level. ► FFR pitch strength decreases when distortion products are masked.
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How are inner hair cells stimulated? Evidence for multiple mechanical drivesOriginal Research ArticlePages 35-50 John J. Guinan Jr.
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Highlights
► Reticular lamina to tectorial membrane gap changes force fluid past IHC stereocilia. ► Four IHC drives result: two excitatory and two inhibitory for upward BM motion. ► Mixtures of these drives explain anomalous auditory-nerve data, including reversals. ► The OHC-MOTILITY drive enhances cochlear output by active processes. ► The results provide a new view of how the cochlea works below 3 kHz.
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