Inside Blood

- Eric Gars and
- Shahin Rafii
It takes 2 to thrombopoies in the vascular niche
Blood 2012 120:2775-2776; doi:10.1182/blood-2012-07-435172
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- Donna E. Reece
Carfilzomib in multiple myeloma: gold, silver, or bronze?
Blood 2012 120:2776-2777; doi:10.1182/blood-2012-08-446534
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- Wassim El Nemer
HU for acute treatment of sickle VOC?
Blood 2012 120:2777-2778; doi:10.1182/blood-2012-08-447102
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- Jerry Ware
Fragmenting the platelet to reduce metastasis
Blood 2012 120:2779-2780; doi:10.1182/blood-2012-08-450072
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- Pavan Reddy
α-1 antitrysin DAMPens GVHD
Blood 2012 120:2780-2781; doi:10.1182/blood-2012-08-442764
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- Marcelo A. Fernandez-Viña
HLA factors in transplantation for nonmalignant hematologic disorders
Blood 2012 120:2781-2782; doi:10.1182/blood-2012-08-446567
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Blood Work

- Fanny Angelot-Delettre and
- Francine Garnache-Ottou
Blastic plasmacytoid dendritic cell neoplasm
Blood 2012 120:2784; doi:10.1182/blood-2012-03-417030
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- Javier Munoz and
- Amr Hanbali
Reactive eosinophilia and thrombosis
Blood 2012 120:2785; doi:10.1182/blood-2012-02-412312
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Plenary Paper

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- Simon C. Pitchford,
- Tracey Lodie,
- and Sara M. Rankin
VEGFR1 stimulates a CXCR4-dependent translocation of megakaryocytes to the vascular niche, enhancing platelet production in mice
Blood 2012 120:2787-2795; published ahead of print May 31, 2012,doi:10.1182/blood-2011-09-378174
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Review Article

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- Edus H. Warren,
- Xinyi Cindy Zhang,
- Shuying Li,
- Wenhong Fan,
- Barry E. Storer,
- Jason W. Chien,
- Michael J. Boeckh,
- Lue Ping Zhao,
- Paul J. Martin,
- and John A. Hansen
Effect of MHC and non-MHC donor/recipient genetic disparity on the outcome of allogeneic HCT
Blood 2012 120:2796-2806; published ahead of print August 2, 2012,doi:10.1182/blood-2012-04-347286
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How I Treat

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- Franco Locatelli,
- Martin Schrappe,
- Maria Ester Bernardo,
- and Sergio Rutella
How I treat relapsed childhood acute lymphoblastic leukemia
Blood 2012 120:2807-2816; published ahead of print August 15, 2012,doi:10.1182/blood-2012-02-265884
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Clinical Trials and Observations

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- David S. Siegel,
- Thomas Martin,
- Michael Wang,
- Ravi Vij,
- Andrzej J. Jakubowiak,
- Sagar Lonial,
- Suzanne Trudel,
- Vishal Kukreti,
- Nizar Bahlis,
- Melissa Alsina,
- Asher Chanan-Khan,
- Francis Buadi,
- Frederic J. Reu,
- George Somlo,
- Jeffrey Zonder,
- Kevin Song,
- A. Keith Stewart,
- Edward Stadtmauer,
- Lori Kunkel,
- Sandra Wear,
- Alvin F. Wong,
- Robert Z. Orlowski,
- and Sundar Jagannath
A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma
Blood 2012 120:2817-2825; published ahead of print July 25, 2012,doi:10.1182/blood-2012-05-425934
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- John A. Liu Yin,
- Michelle A. O'Brien,
- Robert K. Hills,
- Sarah B. Daly,
- Keith Wheatley,
- and Alan K. Burnett
Minimal residual disease monitoring by quantitative RT-PCR in core binding factor AML allows risk stratification and predicts relapse: results of the United Kingdom MRC AML-15 trial
Blood 2012 120:2826-2835; published ahead of print August 8, 2012,doi:10.1182/blood-2012-06-435669
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- John Horan,
- Tao Wang,
- Michael Haagenson,
- Stephen R. Spellman,
- Jason Dehn,
- Mary Eapen,
- Haydar Frangoul,
- Vikas Gupta,
- Gregory A. Hale,
- Carolyn K. Hurley,
- Susana Marino,
- Machteld Oudshoorn,
- Vijay Reddy,
- Peter Shaw,
- Stephanie J. Lee,
- and Ann Woolfrey
Evaluation of HLA matching in unrelated hematopoietic stem cell transplantation for nonmalignant disorders
Blood 2012 120:2918-2924; published ahead of print July 24, 2012,doi:10.1182/blood-2012-03-417758
- Abstract
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Immunobiology

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- Donald N. Forthal,
- Erin E. Gabriel,
- Angela Wang,
- Gary Landucci,
- and Tran B. Phan
Association of Fcγ receptor IIIa genotype with the rate of HIV infection after gp120 vaccination
Blood 2012 120:2836-2842; published ahead of print August 22, 2012,doi:10.1182/blood-2012-05-431361
- Abstract
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Lymphoid Neoplasia

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- David S. Siegel,
- Thomas Martin,
- Michael Wang,
- Ravi Vij,
- Andrzej J. Jakubowiak,
- Sagar Lonial,
- Suzanne Trudel,
- Vishal Kukreti,
- Nizar Bahlis,
- Melissa Alsina,
- Asher Chanan-Khan,
- Francis Buadi,
- Frederic J. Reu,
- George Somlo,
- Jeffrey Zonder,
- Kevin Song,
- A. Keith Stewart,
- Edward Stadtmauer,
- Lori Kunkel,
- Sandra Wear,
- Alvin F. Wong,
- Robert Z. Orlowski,
- and Sundar Jagannath
A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma
Blood 2012 120:2817-2825; published ahead of print July 25, 2012,doi:10.1182/blood-2012-05-425934
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- Christopher J. Ott,
- Nadja Kopp,
- Liat Bird,
- Ronald M. Paranal,
- Jun Qi,
- Teresa Bowman,
- Scott J. Rodig,
- Andrew L. Kung,
- James E. Bradner,
- and David M. Weinstock
BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia
Blood 2012 120:2843-2852; published ahead of print August 17, 2012,doi:10.1182/blood-2012-02-413021
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- Diederik van Bodegom,
- Jun Zhong,
- Nadja Kopp,
- Chaitali Dutta,
- Min-Sik Kim,
- Liat Bird,
- Oliver Weigert,
- Jeffrey Tyner,
- Akhilesh Pandey,
- Akinori Yoda,
- and David M. Weinstock
Differences in signaling through the B-cell leukemia oncoprotein CRLF2 in response to TSLP and through mutant JAK2
Blood 2012 120:2853-2863; published ahead of print August 20, 2012,doi:10.1182/blood-2012-02-413252
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- Supplemental Methods, Figures, and Tables
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- Harvey A. Greisman,
- Zhengfei Lu,
- Albert G. Tsai,
- Timothy C. Greiner,
- Hye Son Yi,
- and Michael R. Lieber
Brief report IgH partner breakpoint sequences provide evidence that AID initiates t(11;14) and t(8;14) chromosomal breaks in mantle cell and Burkitt lymphomas
Blood 2012 120:2864-2867; published ahead of print August 20, 2012,doi:10.1182/blood-2012-02-412791
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- Supplemental Methods, Results, Tables, and Figures

Myeloid Neoplasia

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- John A. Liu Yin,
- Michelle A. O'Brien,
- Robert K. Hills,
- Sarah B. Daly,
- Keith Wheatley,
- and Alan K. Burnett
Minimal residual disease monitoring by quantitative RT-PCR in core binding factor AML allows risk stratification and predicts relapse: results of the United Kingdom MRC AML-15 trial
Blood 2012 120:2826-2835; published ahead of print August 8, 2012,doi:10.1182/blood-2012-06-435669
- Abstract
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Phagocytes, Granulocytes, and Myelopoiesis

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- Eric K. Sackmann,
- Erwin Berthier,
- Edmond W.K. Young,
- Miriam A. Shelef,
- Sarah A. Wernimont,
- Anna Huttenlocher,
- and David J. Beebe
e-Blood Microfluidic kit-on-a-lid: a versatile platform for neutrophil chemotaxis assays
Blood 2012 120:e45-e53; published ahead of print August 22, 2012,doi:10.1182/blood-2012-03-416453
- Abstract
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- Supplemental Methods, Tables, Figures, and Videos

Platelets and Thrombopoiesis

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- Simon C. Pitchford,
- Tracey Lodie,
- and Sara M. Rankin
VEGFR1 stimulates a CXCR4-dependent translocation of megakaryocytes to the vascular niche, enhancing platelet production in mice
Blood 2012 120:2787-2795; published ahead of print May 31, 2012,doi:10.1182/blood-2011-09-378174
- Abstract
- Full Text
- Full Text (PDF)
- Supplemental Figure

Red Cells, Iron, and Erythropoiesis

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- Sasidhar Vemula,
- Jianjian Shi,
- Raghuveer Singh Mali,
- Peilin Ma,
- Yan Liu,
- Philip Hanneman,
- Karl R. Koehler,
- Eri Hashino,
- Lei Wei,
- and Reuben Kapur
ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53
Blood 2012 120:2868-2878; published ahead of print August 13, 2012,doi:10.1182/blood-2011-10-384172
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- Camila Bononi Almeida,
- Christoph Scheiermann,
- Jung-Eun Jang,
- Colette Prophete,
- Fernando Ferreira Costa,
- Nicola Conran,
- and Paul S. Frenette
Hydroxyurea and a cGMP-amplifying agent have immediate benefits on acute vaso-occlusive events in sickle cell disease mice
Blood 2012 120:2879-2888; published ahead of print July 25, 2012,doi:10.1182/blood-2012-02-409524
- Abstract
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- Supplemental Table and Figures

Thrombosis and Hemostasis

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- Wei Zhang,
- Suying Dang,
- Tao Hong,
- Jian Tang,
- Jing Fan,
- Dawei Bu,
- Yanjie Sun,
- Zhugang Wang,
- and Thomas Wisniewski
A humanized single-chain antibody against beta 3 integrin inhibits pulmonary metastasis by preferentially fragmenting activated platelets in the tumor microenvironment
Blood 2012 120:2889-2898; published ahead of print August 9, 2012,doi:10.1182/blood-2012-04-425207
- Abstract
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Transplantation

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- Todd V. Brennan,
- Liwen Lin,
- Xiaopei Huang,
- Diana M. Cardona,
- Zhiguo Li,
- Keith Dredge,
- Nelson J. Chao,
- and Yiping Yang
Heparan sulfate, an endogenous TLR4 agonist, promotes acute GVHD after allogeneic stem cell transplantation
Blood 2012 120:2899-2908; published ahead of print July 3, 2012,doi:10.1182/blood-2011-07-368720
- Abstract
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- Pawel Zerr,
- Katrin Palumbo-Zerr,
- Alfiya Distler,
- Michal Tomcik,
- Stefan Vollath,
- Luis E. Munoz,
- Christian Beyer,
- Clara Dees,
- Friederike Egberts,
- Ilaria Tinazzi,
- Francesco Del Galdo,
- Oliver Distler,
- Georg Schett,
- Bernd M. Spriewald,
- and Jörg H. W. Distler
Inhibition of hedgehog signaling for the treatment of murine sclerodermatous chronic graft-versus-host disease
Blood 2012 120:2909-2917; published ahead of print August 22, 2012,doi:10.1182/blood-2012-01-403428
- Abstract
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Select this article
- John Horan,
- Tao Wang,
- Michael Haagenson,
- Stephen R. Spellman,
- Jason Dehn,
- Mary Eapen,
- Haydar Frangoul,
- Vikas Gupta,
- Gregory A. Hale,
- Carolyn K. Hurley,
- Susana Marino,
- Machteld Oudshoorn,
- Vijay Reddy,
- Peter Shaw,
- Stephanie J. Lee,
- and Ann Woolfrey
Evaluation of HLA matching in unrelated hematopoietic stem cell transplantation for nonmalignant disorders
Blood 2012 120:2918-2924; published ahead of print July 24, 2012,doi:10.1182/blood-2012-03-417758
- Abstract
- Full Text
- Full Text (PDF)

Vascular Biology

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- Andreas Stahl,
- Jean-Sebastian Joyal,
- Jing Chen,
- Przemyslaw Sapieha,
- Aimee M. Juan,
- Colman J. Hatton,
- Dorothy T. Pei,
- Christian G. Hurst,
- Molly R. Seaward,
- Nathan M. Krah,
- Roberta J. Dennison,
- Emily R. Greene,
- Elisa Boscolo,
- Dipak Panigrahy,
- and Lois E. H. Smith
Brief report SOCS3 is an endogenous inhibitor of pathologic angiogenesis
Blood 2012 120:2925-2929; published ahead of print July 12, 2012,doi:10.1182/blood-2012-04-422527
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期刊中心

Inside Blood

It takes 2 to thrombopoies in the vascular niche

Carfilzomib in multiple myeloma: gold, silver, or bronze?

HU for acute treatment of sickle VOC?

Fragmenting the platelet to reduce metastasis

α-1 antitrysin DAMPens GVHD

HLA factors in transplantation for nonmalignant hematologic disorders

Blood Work

Blastic plasmacytoid dendritic cell neoplasm

Reactive eosinophilia and thrombosis

Plenary Paper

VEGFR1 stimulates a CXCR4-dependent translocation of megakaryocytes to the vascular niche, enhancing platelet production in mice

Review Article

Effect of MHC and non-MHC donor/recipient genetic disparity on the outcome of allogeneic HCT

How I Treat

How I treat relapsed childhood acute lymphoblastic leukemia

Clinical Trials and Observations

A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma

Minimal residual disease monitoring by quantitative RT-PCR in core binding factor AML allows risk stratification and predicts relapse: results of the United Kingdom MRC AML-15 trial

Evaluation of HLA matching in unrelated hematopoietic stem cell transplantation for nonmalignant disorders

Immunobiology

Association of Fcγ receptor IIIa genotype with the rate of HIV infection after gp120 vaccination

Lymphoid Neoplasia

A phase 2 study of single-agent carfilzomib (PX-171-003-A1) in patients with relapsed and refractory multiple myeloma

BET bromodomain inhibition targets both c-Myc and IL7R in high-risk acute lymphoblastic leukemia

Differences in signaling through the B-cell leukemia oncoprotein CRLF2 in response to TSLP and through mutant JAK2

Brief report IgH partner breakpoint sequences provide evidence that AID initiates t(11;14) and t(8;14) chromosomal breaks in mantle cell and Burkitt lymphomas

Myeloid Neoplasia

Minimal residual disease monitoring by quantitative RT-PCR in core binding factor AML allows risk stratification and predicts relapse: results of the United Kingdom MRC AML-15 trial

Phagocytes, Granulocytes, and Myelopoiesis

e-Blood Microfluidic kit-on-a-lid: a versatile platform for neutrophil chemotaxis assays

Platelets and Thrombopoiesis

VEGFR1 stimulates a CXCR4-dependent translocation of megakaryocytes to the vascular niche, enhancing platelet production in mice

Red Cells, Iron, and Erythropoiesis

ROCK1 functions as a critical regulator of stress erythropoiesis and survival by regulating p53

Hydroxyurea and a cGMP-amplifying agent have immediate benefits on acute vaso-occlusive events in sickle cell disease mice

Thrombosis and Hemostasis

A humanized single-chain antibody against beta 3 integrin inhibits pulmonary metastasis by preferentially fragmenting activated platelets in the tumor microenvironment

Transplantation

Heparan sulfate, an endogenous TLR4 agonist, promotes acute GVHD after allogeneic stem cell transplantation

Inhibition of hedgehog signaling for the treatment of murine sclerodermatous chronic graft-versus-host disease

Evaluation of HLA matching in unrelated hematopoietic stem cell transplantation for nonmalignant disorders

Vascular Biology

Brief report SOCS3 is an endogenous inhibitor of pathologic angiogenesis

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