Article Title  | 
              Author(s) | Pages | ||
|---|---|---|---|---|
                Cover 1
                
                
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              OFC | |||
                Brief Overview of This Month's JACI
                
                
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              3A-4A | |||
                Table of Contents
                
                
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              6A-18A | |||
                Editorial Board
                
                
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              19A | |||
| Reader services | ||||
| Article Title | Author(s) | Pages | ||
                Information for Readers
                
                
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              20A | |||
                News & Notes
                
                
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              22A-24A | |||
                CME Activities Calendar
                
                
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              25A-26A | |||
| News beyond our pages | ||||
| Article Title | Author(s) | Pages | ||
                News Beyond Our Pages
                
                
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              Marc E. Rothenberg, Jean Bousquet | 1-2 | ||
| Reviews and feature articles | ||||
| Clinical reviews in allergy and immunology | ||||
| Article Title | Author(s) | Pages | ||
                Trichuris suis ova: Testing a helminth-based therapy as an extension of the hygiene hypothesis
                
                
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              Marie-Hélène Jouvin, Jean-Pierre Kinet | 3-10 | ||
| Continuing Medical Education examination | ||||
| Article Title | Author(s) | Pages | ||
                Trichuris suis ova: Testing a helminth-based therapy as an extension of the hygiene hypothesis
                
                
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              11-12 | |||
| Mechanisms of allergic diseases | ||||
| Article Title | Author(s) | Pages | ||
                Molecular mechanisms of hookworm disease: Stealth, virulence, and vaccines
                
                
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              Mark S. Pearson, Leon Tribolet, Cinzia Cantacessi, Maria Victoria Periago, et al. | 13-21 | ||
| Editorials | ||||
| Article Title | Author(s) | Pages | ||
                The public health benefits of air pollution control
                
                
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              Jinghong Li, Gary Ewart, Monica Kraft, Patricia W. Finn | 22-23 | ||
                Statement regarding “The public health benefits of air pollution control”
                
                
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              Dennis K. Ledford, A. Wesley Burks, Mark Ballow, Linda Cox, et al. | 24 | ||
| Task force report | ||||
| Article Title | Author(s) | Pages | ||
                Adverse reactions to vaccines practice parameter 2012 update
                
                
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              John M. Kelso, Matthew J. Greenhawt, James T. Li, Richard A. Nicklas, et al. | 25-43 | ||
| Current perspectives | ||||
| Article Title | Author(s) | Pages | ||
                Does diversity of environmental microbial exposure matter for the occurrence of allergy and asthma?
                
                
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              Dick Heederik, Erika von Mutius | 44-50 | ||
| The Editors' choice | ||||
| Article Title | Author(s) | Pages | ||
                The Editors' Choice
                
                
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              Donald Y.M. Leung, Stanley J. Szefler, Associate Editors of the JACI | 51-52 | ||
| Asthma and lower airway disease | ||||
| Article Title | Author(s) | Pages | ||
                Corticosteroid use and bone mineral accretion in children with asthma: Effect modification by vitamin D
                
                
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              Sze Man Tse, H. William Kelly, Augusto A. Litonjua, Mark L. Van Natta, et al. | 53-60.e4 | ![]()  | 
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                Ventilation heterogeneity predicts asthma control in adults following inhaled corticosteroid dose titration
                
                
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              Claude S. Farah, Gregory G. King, Nathan J. Brown, Matthew J. Peters, et al. | 61-68 | ||
                Methacholine challenge test: Diagnostic characteristics in asthmatic patients receiving controller medications
                
                
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              Kaharu Sumino, Elizabeth A. Sugar, Charles G. Irvin, David A. Kaminsky, et al. | 69-75.e6 | ![]()  | 
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                Case-control admixture mapping in Latino populations enriches for known asthma-associated genes
                
                
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              Dara G. Torgerson, Christopher R. Gignoux, Joshua M. Galanter, Katherine A. Drake, et al. | 76-82.e12 | ![]()  | 
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                Genome-wide association study of the age of onset of childhood asthma
                
                
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              Erick Forno, Jessica Lasky-Su, Blanca Himes, Judie Howrylak, et al. | 83-90.e4 | ![]()  | 
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                Determinants of asthma after severe respiratory syncytial virus bronchiolitis
                
                
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              Leonard B. Bacharier, Rebecca Cohen, Toni Schweiger, Huiquing Yin-DeClue, et al. | 91-100.e3 | ![]()  | 
            |
| Editorial | ||||
| Article Title | Author(s) | Pages | ||
                Why does respiratory syncytial virus appear to cause asthma?
                
                
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              Darryl J. Adamko, Michael Friesen | 101-102 | ||
                Novel severe wheezy young children phenotypes: Boys atopic multiple-trigger and girls nonatopic uncontrolled wheeze
                
                
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              Jocelyne Just, Rahele Gouvis-Echraghi, Remy Couderc, Nathalie Guillemot-Lambert, et al. | 103-110.e8 | ![]()  | 
            |
| Editorial | ||||
| Article Title | Author(s) | Pages | ||
                Toward a definition of asthma phenotypes in childhood: Making a long way shorter?
                
                
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              Ulrich Wahn, Paolo M. Matricardi | 111-112 | ||
| Rhinitis, sinusitis, and upper airway disease | ||||
| Article Title | Author(s) | Pages | ||
                Intrauterine sensitization of allergen-specific IgE analyzed by a highly sensitive new allergen microarray
                
                
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              Norio Kamemura, Hitomi Tada, Naoki Shimojo, Yoshinori Morita,et al. | 113-121.e2 | ![]()  | 
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                Responses to ragweed pollen in a pollen challenge chamber versus seasonal exposure identify allergic rhinoconjunctivitis endotypes
                
                
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              Robert L. Jacobs, Nathan Harper, Weijing He, Charles P. Andrews, et al. | 122-127.e8 | ![]()  | 
            |
| Editorial | ||||
| Article Title | Author(s) | Pages | ||
                Correlation between a pollen challenge chamber and a natural allergen exposure study design for eliciting ocular and nasal symptoms: Early evidence supporting a paradigm shift in drug investigation?
                
                
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              Jonathan A. Bernstein | 128-129 | ||
| Atopic dermatitis and skin disease | ||||
| Article Title | Author(s) | Pages | ||
                Development of atopic dermatitis according to age of onset and association with early-life exposures
                
                
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              Caroline Roduit, Remo Frei, Georg Loss, Gisela Büchele,et al. | 130-136.e5 | ![]()  | 
            |
                How should an incident case of atopic dermatitis be defined? A systematic review of primary prevention studies
                
                
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              Eric L. Simpson, Laura E. Keck, Joanne R. Chalmers, Hywel C. Williams | 137-144 | ||
                IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis
                
                
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              James G. Krueger, Scott Fretzin, Mayte Suárez-Fariñas, Patrick A. Haslett,et al. | 145-154.e9 | ![]()  | 
            |
| Correction | ||||
| Article Title | Author(s) | Pages | ||
                Correction
                
                
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              154 | |||
| Food, drug, insect sting allergy, and anaphylaxis | ||||
| Article Title | Author(s) | Pages | ||
                Double positivity to bee and wasp venom: Improved diagnostic procedure by recombinant allergen–based IgE testing and basophil activation test including data about cross-reactive carbohydrate determinants
                
                
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              Bernadette Eberlein, Lilian Krischan, Ulf Darsow, Markus Ollert, et al. | 155-161 | ||
                Ultrarush versus semirush initiation of insect venom immunotherapy: A randomized controlled trial
                
                
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              Simon G.A. Brown, Michael D. Wiese, Pauline van Eeden, Shelley F. Stone, et al. | 162-168 | ||
                Generalized urticaria induced by the Na-ASP-2 hookworm vaccine: Implications for the development of vaccines against helminths
                
                
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              David J. Diemert, Antonio G. Pinto, Janaina Freire, Amar Jariwala, et al. | 169-176.e6 | ![]()  | 
            |
| Immune deficiencies, infection, and systemic immune disorders | ||||
| Article Title | Author(s) | Pages | ||
                Defining combined immunodeficiency
                
                
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              Chaim M. Roifman, Raz Somech, Fotini Kavadas, Linda Pires, et al. | 177-183 | ||
| Mechanisms of allergy and clinical immunology | ||||
| Article Title | Author(s) | Pages | ||
                A critical role of IL-33 in experimental allergic rhinitis
                
                
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              Yoko Haenuki, Kazufumi Matsushita, Shizue Futatsugi-Yumikura, Ken J. Ishii, et al. | 184-194.e11 | ![]()  | 
            |
                Imidazoquinoline Toll-like receptor 8 agonists activate human newborn monocytes and dendritic cells through adenosine-refractory and caspase-1–dependent pathways
                
                
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              Victoria J. Philbin, David J. Dowling, Leighanne C. Gallington, Guadalupe Cortés, et al. | 195-204.e9 | ![]()  | 
            |
                Mast cell TNF receptors regulate responses to Mycoplasma pneumoniae in surfactant protein A (SP-A)−/− mice
                
                
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              Bethany J. Hsia, Julie G. Ledford, Erin N. Potts-Kant, Vinayak S. Nikam, et al. | 205-214.e2 | ![]()  | 
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                Epigenetic modifications and improved regulatory T-cell function in subjects undergoing dual sublingual immunotherapy
                
                
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              Ravi S. Swamy, Neha Reshamwala, Tessa Hunter, Soujanya Vissamsetti, et al. | 215-224.e7 | ![]()  | 
            |
                Airway epithelial cells activate TH2 cytokine production in mast cells through IL-1 and thymic stromal lymphopoietin
                
                
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              Deepti R. Nagarkar, Julie A. Poposki, Michael R. Comeau, Assel Biyasheva,et al. | 225-232.e4 | ![]()  | 
            |
                Multiple-checkpoint inhibition of thymic stromal lymphopoietin–induced TH2 response by TH17-related cytokines
                
                
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              Sofia I. Bogiatzi, Maude Guillot-Delost, Antonio Cappuccio, Jean-Christophe Bichet, et al. | 233-240.e5 | ![]()  | 
            |
                Alternaria alternata allergen Alt a 1: A unique β-barrel protein dimer found exclusively in fungi
                
                
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              Maksymilian Chruszcz, Martin D. Chapman, Tomasz Osinski, Robert Solberg,et al. | 241-247.e9 | ![]()  | 
            |
                Molecular mimicry between cockroach and helminth glutathione S-transferases promotes cross-reactivity and cross-sensitization
                
                
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              Helton C. Santiago, Elyse LeeVan, Sasisekhar Bennuru, Flavia Ribeiro-Gomes,et al. | 248-256.e9 | ![]()  | 
            |
| Editorial | ||||
| Article Title | Author(s) | Pages | ||
                Parasites and allergic disease: Another piece of the puzzle
                
                
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              Robert K. Bush | 257-258 | ||
| Letters to the Editor | ||||
| Article Title | Author(s) | Pages | ||
                TH2 cytokines increase kallikrein 7 expression and function in patients with atopic dermatitis
                
                
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              Shin Morizane, Kenshi Yamasaki, Ai Kajita, Kazuko Ikeda, et al. | 259-261.e1 | ![]()  | 
            |
                Accurate oral food challenge requires a cumulative dose on a subsequent day
                
                
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              Bodo Niggemann, Lars Lange, Antje Finger, Mandy Ziegert, et al. | 261-263 | ||
                A self-regulation intervention can improve quality of life for families with food allergy
                
                
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              Alan P. Baptist, Sara I. Dever, Matthew J. Greenhawt, Nancy Polmear-Swendris, et al. | 263-265.e6 | ![]()  | 
            |
                Ascaris sensitization is associated with aeroallergen sensitization and airway hyperresponsiveness but not allergic disease in urban Africa
                
                
  | 
              Michael Levin, Rudzani Muloiwa, Peter Le Souëf, Cassim Motala | 265-267 | ||
                Fungal and atopic sensitization are low among farmers in the Agricultural Health Study
                
                
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              Stacy M. Endres, Brett J. Green, Paul K. Henneberger, Dori R. Germolec, et al. | 267-270.e1 | ![]()  | 
            |
                Helminth infection is associated with decreased basophil responsiveness in human beings
                
                
  | 
              David Larson, Philip J. Cooper, Marc P. Hübner, Jorge Reyes, et al. | 270-272 | ||
                Human CD20+CD43+CD27+CD5− B cells generate antibodies to capsular polysaccharides of Streptococcus pneumoniae
                
                
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              Bert Verbinnen, Kris Covens, Leen Moens, Isabelle Meyts, et al. | 272-275 | ||
| Correspondence | ||||
| Article Title | Author(s) | Pages | ||
                Comparable IgE reactivity to natural and recombinant Api m 1 in cross-reactive carbohydrate determinant–negative patients with bee venom allergy
                
                
  | 
              Thilo Jakob, Julian Köhler, Simon Blank, Ulrika Magnusson, et al. | 276-278 | ||
                Reply
                
                
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              Peter Korošec, Mitja Košnik | 278-279 | ||
                Possible roles of 2 basidiomycetous fungi in allergic fungal respiratory disease
                
                
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              Haruhiko Ogawa, Masaki Fujimura, Yasuo Takeuchi, Koichi Makimura | 279-280 | ||
                Reply
                
                
  | 
              Alan P. Knutsen, Robert K. Bush | 280 | ||
                Basophil activation test and autologous serum skin test: Not overlapping tests in chronic urticaria
                
                
  | 
              Alberto Tedeschi, Riccardo Asero, Massimo Cugno | 280-281 | ||
                Reply
                
                
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              Thomas Gentinetta, Werner J. Pichler, Oliver V. Hausmann | 281 | ||
| Correction | ||||
| Article Title | Author(s) | Pages | ||
                Correction
                
                
  | 
              282 | |||
| Maintenance of Certification clinical management series | ||||
| Article Title | Author(s) | Pages | ||
                Vaccines in the assessment of patients for immune deficiency
                
                
  | 
              Mark Ballow | 283-284.e5 | ![]()  | 
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