期刊阅览

中文标题: 日本Wilson病人接受长期锌治疗的效果：有效性、稳定性和铜代谢

英文标题: Effects of long-term zinc treatment in Japanese patients with Wilson disease: efficacy, stability, and copper metabolism

作者: Norikazu Shimizu, Junko Fujiwara, Shin Ohnishi, Ma...

全文: Wilson disease is an autosomal recessive disorder with copper metabolism. In Japan, the standard treatment is the administration of copper chelating agents, such as D-penicillamine and trientine. ...

往期免费全文 [栏目介绍]

Volume 156 , Issue 6 , Year 2010
日本Wilson病人接受长期锌治疗的效果：有效性、稳定性和铜代谢
Effects of long-term zinc treatment in Japanese patients with Wilson disease: efficacy, stability, and copper metabolism

Volume 156 , Issue 5 , Year 2010
利马前列素通过增加胰岛素样生长因子I的合成来减少脊髓损伤大鼠的运动障碍
Limaprost reduces motor disturbances by increasing the production of insulin-like growth factor I in rats subjected to spinal cord injury

Volume 156 , Issue 4 , Year 2010
2型糖尿病患者血浆硒浓度的初步研究
Plasma selenoproteins concentrations in type 2 diabetes mellitus—a pilot study

Volume 156 , Issue 3 , Year 2010
干细胞疗法治疗1型糖尿病
Stem cell approaches for the treatment of type 1 diabetes mellitus

Volume 156 , Issue 1 , Year 2010
内皮脂酶在动脉粥样硬化中的作用
Role of endothelial lipase in atherosclerosis

Volume 156 , Issue 2 , Year 2010
利用RB1基因突变评估转移性视网膜母细胞瘤微小残留病
Using RB1 mutations to assess minimal residual disease in metastatic retinoblastoma

Volume 155 , Issue 6 , Year 2010
布洛芬诱导的超敏综合征
Ibuprofen-induced hypersensitivity syndrome

Volume 155 , Issue 5 , Year 2010
新型人血干细胞：治疗1型糖尿病的双刃剑
New type of human blood stem cell: a double-edged sword for the treatment of type 1 diabetes

Volume 155 , Issue 4 , Year 2010
异物诱导发生的肉芽组织是成年人干细胞的一个来源
Foreign body-induced granulation tissue is a source of adult stem cells

Volume 155 , Issue 3 , Year 2010
α-球蛋白基因变异和缺失的新的快速检测方法
Novel technique for rapid detection of α-globin gene mutations and deletions

Volume 155 , Issue 2 , Year 2010
失血性低血压的早期生理反应
Early physiologic responses to hemorrhagic hypotension

Volume 155 , Issue 1 , Year 2010
干细胞治疗急性心肌梗死：临床试验回顾
Stem cell therapy in acute myocardial infarction: a review of clinical trials

Volume 154 , Issue 6 , Year 2009
基因组与个体化医学：基础与应用
Genomic and personalized medicine: foundations and applications

Volume 154 , Issue 5 , Year 2009
热休克蛋白70基因变异体的相互作用与新疆和田地区维吾尔族人的长寿现象
Interactive association of heat shock protein 70 genes variants with natural longevity in Xinjiang Hetian Uygur ethnicity

Volume 154 , Issue 4 , Year 2009
哮喘气道平滑肌靶向治疗
Targeting the airway smooth muscle for asthma treatment

Volume 154 , Issue 3 , Year 2009
肺活量测定在慢性阻塞性肺病诊断中的使用及改善护理质量的措施
Use of spirometry in the diagnosis of chronic obstructive pulmonary disease and efforts to improve quality of care

Volume 154 , Issue 2 , Year 2009
系统性红斑狼疮早期血管损伤：损伤与修复的失衡？
Premature vascular damage in systemic lupus erythematosus: an imbalance of damage and repair?

Volume 154 , Issue 1 , Year 2009
结核病与宿主代谢：古老的关联与最新的见解
Tuberculosis and host metabolism: ancient associations, fresh insights

全部学科

病例分析

甲状腺功能亢进合并黄疸

王燕燕王曙

上海交通大学附属瑞金医院内分泌科

患者，女，69岁。2009年1月无明显诱因下出现乏力，当时程度较轻，未予以重视。2009年3月患者乏力症状加重，尿色逐渐加深，大便习惯改变，颜色变淡。4月18日入我院感染科治疗，诉轻度头晕、心慌，体重减轻10kg。无肝区疼痛，无发热，无腹痛、腹泻、腹胀、里急后重，无恶性、呕吐等。入院半月前于外院就诊，查肝功能：ALT 601IU/L，AST 785IU/L，TBIL 97.7umol/L，白蛋白 41g/L，甲状腺功能：游离T3 30.6pmol/L，游离T4 51.9pmol/L，心电图示快速房颤。

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