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早期外阴癌直肠阴道结节计数和腹股沟复发的相关性研究：一项妇科肿瘤组研究
Node count and groin recurrence in early vulvar cancer: A Gynecologic Oncology Group study
Stehman FB, Ali S, DiSaia PJ  2009/9/21 19:30:53 
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Gynecol Oncol, 2009,
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Objective:
To determine if low node count from superficial groin dissection correlated with first recurrence in the groin for patients with early vulvar cancer.

Methods:
The Gynecologic Oncology Group (GOG) conducted a trial for patients with early stage squamous vulvar cancer, lesions <2cm in size and <5mm in depth. All fatty tissue below the inguinal ligament, medial to the sartorious and lateral to the adductor longus was removed. Incision of the fascia and skeletonizing the femoral vessels were not required. For this secondary analysis, we reviewed the records of all patients to assess node counts.

Results:
Of the 113 patients eligible for the study, 104 patients (with 117 dissected groins) did not have a first recurrence in the groin. The median number of negative nodes was 9 (range: 1–26). Nine patients (with 9 dissected groins) suffered a first recurrence in the groin. The median number of negative nodes removed per groin was 7 (range: 4–22). There were no significant differences between patients with first recurrence in the groin and those without (p value=0.7475). There was a broad overlap of the confidence intervals.

Conclusions:
We were unable to show that groin failure after superficial lymphadenectomy was a result of low lymph node count. The small number of recurrences made firm conclusions impossible. Variations in anatomy and other factors may make node counting an unreliable measure of surgical quality.
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甲状腺功能亢进合并黄疸

 王燕燕 王曙

上海交通大学附属瑞金医院内分泌科

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