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"云样增强"是视神经脊髓炎独有的磁共振影像异常
"Cloud-like Enhancement" Is a Magnetic Resonance Imaging Abnormality Specific to Neuromyelitis Optica
Ito S, Mori M, Makino T.  2010/11/29 17:52:37 
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Ann Neurol, 2009,
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Neuromyelitis optica (NMO) is presumably mediated by an autoantibody against aquaporin-4 densely expressed at the blood-brain barrier. In 18 patients with NMO brain magnetic resonance imaging (MRI) findings were systematically reviewed. Brain MRI abnormalities were found for 89% of the patients and the most prominent feature was "cloud-like enhancement " multiple patchy enhancing lesions with blurred margin found in 90% of the patients with positive contrast enhancement. In NMO brain MRI abnormalities are frequent and cloud-like enhancement appears to be an MRI finding specific to NMO possibly caused by primary involvement of the blood-brain barrier by the autoantibodies.
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患者，女，69岁。2009年1月无明显诱因下出现乏力，当时程度较轻，未予以重视。2009年3月患者乏力症状加重，尿色逐渐加深，大便习惯改变，颜色变淡。4月18日入我院感染科治疗，诉轻度头晕、心慌，体重减轻10kg。无肝区疼痛，无发热，无腹痛、腹泻、腹胀、里急后重，无恶性、呕吐等。入院半月前于外院就诊，查肝功能：ALT 601IU/L，AST 785IU/L，TBIL 97.7umol/L，白蛋白 41g/L，甲状腺功能：游离T3 30.6pmol/L，游离T4 51.9pmol/L，心电图示快速房颤。
 

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