全球精选文摘 - 英国女性的输卵管绝育、全因死亡和癌症：皇家全科医师学会口服避孕研究的证据

Tubal sterilization, all-cause death, and cancer among women in the United Kingdom: evidence from the Royal College of General Practitioners' Oral Contraception Study

Iversen L, Hannaford PC, Elliott AM 2009/5/27 10:50:39

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Am J Obstet Gynecol, 2007,

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Abstract

Objective:

The purpose of this study was to examine the relationship between tubal sterilization and subsequent all-cause death and the risk of any gynecologic and breast cancer in women in the United Kingdom.

Study Design:

A cohort study was conducted with 2801 sterilized women and 2801 nonsterilized women who were identified from the UK Royal College of General Practitioners' Oral Contraception Study. Adjusted hazard ratios and 95% CIs were calculated with Cox regression.

Results:

Tubal sterilization was not associated with significantly altered risks of subsequent all-cause death or cancer. Tubal sterilization was associated with a nonsignificant reduced risk of subsequent gynecologic (adjusted hazard ratio, 0.84; 95% CI, 0.52-1.37) and breast cancer (adjusted hazard ratio, 0.88; 95% CI, 0.67-1.16).

Conclusion:

The absence of increased long-term death and cancer risk is reassuring, given that many women have chosen this method of contraception.

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疾病资源中心

高血压	慢性阻塞性肺病
脂肪性肝病	糖尿病
卒中	肺癌
冠心病	子宫内膜异位症
结直肠癌	乳腺癌
心力衰竭	心律失常

病例分析 [栏目介绍]

甲状腺功能亢进合并黄疸

王燕燕王曙

上海交通大学附属瑞金医院内分泌科

患者，女，69岁。2009年1月无明显诱因下出现乏力，当时程度较轻，未予以重视。2009年3月患者乏力症状加重，尿色逐渐加深，大便习惯改变，颜色变淡。4月18日入我院感染科治疗，诉轻度头晕、心慌，体重减轻10kg。无肝区疼痛，无发热，无腹痛、腹泻、腹胀、里急后重，无恶性、呕吐等。入院半月前于外院就诊，查肝功能：ALT 601IU/L，AST 785IU/L，TBIL 97.7umol/L，白蛋白 41g/L，甲状腺功能：游离T3 30.6pmol/L，游离T4 51.9pmol/L，心电图示快速房颤。

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