全球精选文摘 - 曾有双胎妊娠早产史的妇女是否在其后的单胎妊娠中早产风险增加？

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曾有双胎妊娠早产史的妇女是否在其后的单胎妊娠中早产风险增加？

Are women who have had a preterm twin delivery at greater risk of preterm birth in a subsequent singleton pregnancy?

Facco FL, Nash K, Grobman WA 2009/5/27 10:50:39

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Am J Obstet Gynecol, 2007,

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Abstract
Objective:
The purpose of this study was to determine whether preterm birth of twins is associated with an increased risk of preterm birth in a subsequent singleton pregnancy.

Study Design:
All patients who delivered a twin gestation and a subsequent singleton pregnancy at Northwestern Memorial Hospital during a 10-year period were identified. We used a cohort study design, comparing the outcomes of the singleton pregnancies in women with preterm twin deliveries to those pregnancies with term twin deliveries.

Results:
One hundred sixty-seven women delivered twins followed by a singleton pregnancy. Women whose twin delivery was preterm (n=99) were more likely than those who had delivered a term twin pregnancy (n=68) to deliver a subsequent preterm singleton pregnancy (13.1% vs 2.9%; odds ratio, 5.0; 95% CI, 1.1, 22.9).

Conclusion:
Preterm birth of twins is associated with an increased risk of preterm delivery in a subsequent singleton pregnancy.

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疾病资源中心

高血压	慢性阻塞性肺病
脂肪性肝病	糖尿病
卒中	肺癌
冠心病	子宫内膜异位症
结直肠癌	乳腺癌
心力衰竭	心律失常

病例分析 [栏目介绍]

甲状腺功能亢进合并黄疸

王燕燕王曙

上海交通大学附属瑞金医院内分泌科

患者，女，69岁。2009年1月无明显诱因下出现乏力，当时程度较轻，未予以重视。2009年3月患者乏力症状加重，尿色逐渐加深，大便习惯改变，颜色变淡。4月18日入我院感染科治疗，诉轻度头晕、心慌，体重减轻10kg。无肝区疼痛，无发热，无腹痛、腹泻、腹胀、里急后重，无恶性、呕吐等。入院半月前于外院就诊，查肝功能：ALT 601IU/L，AST 785IU/L，TBIL 97.7umol/L，白蛋白 41g/L，甲状腺功能：游离T3 30.6pmol/L，游离T4 51.9pmol/L，心电图示快速房颤。

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