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| 中国人血清CXC趋化因子配体5水平升高与高胆固醇血症相关但并不会导致胰岛素抵抗加重 |
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| Elevated serum chemokine CXC ligand 5 levels are associated with hypercholesterolemia but not a worsening of insulin resistance in Chinese people |
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| Yang Z Zhang Z, Wen J, Wang X Lu B, Yang Z Zhang W, Wang M, Feng X, Ling Cb Wu Sc Hu R 2010/9/10 16:38:00 |
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Journal of Clinical Endocrinology and Metabolism, 2010, Volume 95, Issue 8
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However, serum resistin CXCL5 was not associated with body mass index, percent body fat, fasting glucose, insulin levels, and homeostasis model assessment index-insulin resistance (r = 0.01, 0.01, 0.01, 0.04, and 0.03, respectively, all P > 0.05). Conclusions: Elevated circulating CXCL5 concentrations were associated with higher risk of hypercholesterolemia in middle-aged and elderly Chinese independent of obesity, inflammation, adipokines, and other risk factors but not insulin resistance. Copyright © 2010 by The Endocrine Society.
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| Correspondence Address: Hu, R; Department of Endocrinology and Metabolism, Huashan Hospital, Fudan University, no. 12 Wulumuqi Middle Road, Shanghai 200040, China, email:renminghu@fudan.edu.cn |
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 疾病资源中心
王燕燕 王曙
上海交通大学附属瑞金医院内分泌科
患者，女，69岁。2009年1月无明显诱因下出现乏力，当时程度较轻，未予以重视。2009年3月患者乏力症状加重，尿色逐渐加深，大便习惯改变，颜色变淡。4月18日入我院感染科治疗，诉轻度头晕、心慌，体重减轻10kg。无肝区疼痛，无发热，无腹痛、腹泻、腹胀、里急后重，无恶性、呕吐等。入院半月前于外院就诊，查肝功能：ALT 601IU/L，AST 785IU/L，TBIL 97.7umol/L，白蛋白 41g/L，甲状腺功能：游离T3 30.6pmol/L，游离T4 51.9pmol/L，心电图示快速房颤。
医学数据库
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