中国作者重要发表 - 中国慢性堵塞性肺病患者中St George呼吸问卷的评价与临床解读



中国慢性堵塞性肺病患者中St George呼吸问卷的评价与临床解读





Validation and clinical interpretation of the St George's Respiratory Questionnaire among COPD patients, China





Xu W., Collet J.-P., Shapiro S., Lin Y., Yang T., Wang C., Bourbeau J. 2009/5/29 18:39:31

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International Journal of Tuberculosis and Lung Disease, 2009, Volume 13, Issue 2




SETTING: Although the St George's Respiratory Questionnaires in Mandarin-Chinese (SGRQ-MC) have been used in China, few data are available on the translation and adaptation process, psychometric properties and clinical meaning. It is therefore difficult to adequately evaluate the equivalence of this instrument in Chinese populations. OBJECTIVE: To evaluate the psychometric properties of a culturally translated SGRQ-MC, and to estimate clinically important differences (CID) for the SGRQ in chronic obstructive pulmonary disease (COPD) patients in China. DESIGN: SGRQ was translated into Mandarin using standardised forward and backward translation procedures. Health status and clinical data were collected at baseline in 491 patients with stable COPD and again after 1 week in 131 randomly selected patients. All patients were followed up monthly and assessed during exacerbations and at 1 year. RESULTS: The SGRQ-MC showed good internal consis-tency, test-retest reliability, convergent validity and known-group validity. Responsiveness was shown by significant changes in SGRQ-MC scores between stable stage and exacerbation (P < 0.0001). The estimated CID for the total score ranged from 3.1 (95%CI -0.3-6.5) to 7.7 (95 %CI-1.7-17.2). CONCLUSION: This SGRQ-MC is a reliable, valid and responsive instrument for quality of life evaluation in COPD patients in China. As it is culturally and clinically equivalent to other versions, measures can be compared among countries. ©2009 The Union.



Correspondence Address: Wang, C.; Beijing Institute of Respiratory Medicine, Beijing Chaoyang Hospital, No 8 Bai Jia Zhuang Road, Chaoyang District, Beijing 100020, China; email: cyh-birm@263.net



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疾病资源中心

高血压	慢性阻塞性肺病
脂肪性肝病	糖尿病
卒中	肺癌
冠心病	子宫内膜异位症
结直肠癌	乳腺癌
心力衰竭	心律失常

病例分析

甲状腺功能亢进合并黄疸

王燕燕王曙

上海交通大学附属瑞金医院内分泌科

患者，女，69岁。2009年1月无明显诱因下出现乏力，当时程度较轻，未予以重视。2009年3月患者乏力症状加重，尿色逐渐加深，大便习惯改变，颜色变淡。4月18日入我院感染科治疗，诉轻度头晕、心慌，体重减轻10kg。无肝区疼痛，无发热，无腹痛、腹泻、腹胀、里急后重，无恶性、呕吐等。入院半月前于外院就诊，查肝功能：ALT 601IU/L，AST 785IU/L，TBIL 97.7umol/L，白蛋白 41g/L，甲状腺功能：游离T3 30.6pmol/L，游离T4 51.9pmol/L，心电图示快速房颤。

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