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心尖圆锥率:评价心肌梗死后左室心尖几何学的一种新指标 |
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Apical conicity ratio: A new index on left ventricular apical geometry after myocardial infarction |
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Fan H, Zheng Z, Feng W, Zhang Y, Jin L, Li P, Hu S 2010/12/1 10:15:00 |
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Journal of Thoracic and Cardiovascular Surgery, 2010, Volume 140, Issue 6
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Objective: Our objective was to introduce a new index to evaluate left ventricular aneurysm by quantitative analysis of left ventricular apical geometry. Methods: A total of 116 selected subjects underwent magnetic resonance imaging, 28 healthy volunteers, 29 patients with dilated cardiomyopathy, and 59 patients with ischemic heart disease (26 with left ventricular aneurysm; 33 with no aneurysm). The apical conicity ratio was calculated as the ratio of left ventricular apical area over apical triangle. Results: Diastolic apical conicity ratio of patients with left ventricular aneurysm was 1.62 ± 0.20 and systolic apical conicity ratio was 1.78 ± 0.43. After left ventricular reconstruction, the diastolic apical conicity ratio decreased to 1.47 ± 0.23 and the systolic ratio to 1.51 ± 0.21, which came close to the normal level, whereas other global indices remained. In patients with dilated cardiomyopathy, sphericity index and eccentricity index increased significantly without changes in the apical conicity ratio. Among patients with ischemic heart disease, the apical conicity ratio of the group with left ventricular aneurysm was significantly higher than that of the group without an aneurysm when the other indices between the 2 groups showed no statistically difference. Receiver operating characteristic curves showed only apical conicity ratio had high power of discriminating left ventricular aneurysm from no aneurysm. Conclusions: The new index, apical conicity ratio, can be used to quantify the regional left ventricular deformation, especially in patients with left ventricular aneurysm resulting from myocardial infarction. © 2010 by The American Association for Thoracic Surgery.
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Correspondence Address: Hu, S.; Department of Cardiovascular Surgery, Fu Wai Hospital, Chinese Academy of Medical Sciences, Beilishi Rd 167, Beijing 1000037, China; email:shengshouhu@yahoo.com |
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疾病资源中心
王燕燕 王曙
上海交通大学附属瑞金医院内分泌科
患者,女,69岁。2009年1月无明显诱因下出现乏力,当时程度较轻,未予以重视。2009年3月患者乏力症状加重,尿色逐渐加深,大便习惯改变,颜色变淡。4月18日入我院感染科治疗,诉轻度头晕、心慌,体重减轻10kg。无肝区疼痛,无发热,无腹痛、腹泻、腹胀、里急后重,无恶性、呕吐等。入院半月前于外院就诊,查肝功能:ALT 601IU/L,AST 785IU/L,TBIL 97.7umol/L,白蛋白 41g/L,甲状腺功能:游离T3 30.6pmol/L,游离T4 51.9pmol/L,心电图示快速房颤。
医学数据库
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