Handbook of Basal Ganglia Structure and Function
- 类型：
- 英文原版
- ISBN：
- 9780123747679
- eISBN：
- 9780080912158
- 出版社：
- Academic Press
- 出版日期：
- 2010-03-17
- 页码：
- 700
- 装帧：
- 电子版
- 价格：
- EUR 155.00
- 购买渠道：
- Elsevier书店
- 中文标题：
- 基底神经节结构和功能
- 作 者：
- Heinz Steiner, Kuei Tseng
- 中文简介：
-
基底神经节由一系列前脑核区组成，这些核区和大脑皮质、海马及脑干相互交联。基底神经节通路参与到多种脑功能，包括运动控制、学习、感知运动整合、奖励和认知功能的发挥中。基底神经节对正常脑功能的影响可以从不同类型与基底神经节紊乱相关的疾病中窥见一斑，这些疾病包括帕金森病、妥瑞症、亨廷顿舞蹈病、脑瘫、注意力缺陷多动症、强迫症、肌张力障碍、精神兴奋剂的成瘾性等。
本书对基底神经节的结构和功能性组织进行综述回顾，重点关注在过去10-15年间这一领域取得的成就。全书共分5部分，首先，从基底神经节的解剖学开始介绍，接着对近来在解剖学、细胞、分子、细胞生理学机制等各方面取得的研究进展进行详细描述。最后以基底神经节正常和异常时对行为和临床影响结尾。 - 英文简介：
-
no other volumes which cover the broad range of structural and functional aspects of the basal ganglia, with an outlook towards clinical relevance.
The Basal Ganglia comprise a group of forebrain nuclei that are interconnected with the cerebral cortex, thalamus and brainstem. Basal ganglia circuits are involved in various functions including motor control and learning, sensorimotor integration, reward and cognition. The importance of the basal ganglia for normal brain function and behavior is emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction. These include Parkinson's disease, Tourette's syndrome, Huntington's disease, cerebral palsy, attention-deficit hyperactivity disorder, obsessive-compulsive disorder, dystonia, psychostimulant addiction and others.
The proposed Handbook will provide a comprehensive overview of the structural and functional organization of the basal ganglia, with special emphasis on the progress achieved over the last 10-15 years. The chapters will be written by leading researchers who have made major contributions in this field, many of which have already written authoritative reviews on their subjects. The book is organized in 5 parts. The first, introductory part describes the general anatomical organization and provides a review of the evolution of the basal ganglia, from cell type to circuits. The second, third and fourth parts give detailed accounts of specific recent advances in anatomy, cellular/molecular, and cell-physiological mechanisms, respectively. The fifth part describes recent advances in our understanding of behavioral and clinical aspects of basal ganglia function and dysfunction.
