Growth Factors and Their Receptors in Cell Differentiation, Cancer and Cancer Therapy
- 类型：
- 英文原版
- ISBN：
- 9780123878199
- eISBN：
- 9780123878205
- 出版社：
- Elsevier
- 出版日期：
- 2011-07-12
- 页码：
- 368
- 装帧：
- 电子版
- 价格：
- EUR 108.00
- 购买渠道：
- Elsevier书店
- 中文标题：
- 细胞分化、癌症和癌症治疗中的生长因子及其受体
- 作 者：
- G Sherbet
- 中文简介：
-
近年来，对生长因子的重视方兴未艾，而对它们作用模式的阐述帮助学者们认识到生长因子、它们的受体以及与它们的功能相关的下游信号通路元件可以成为治疗管理人类疾病的潜在靶点。针对生长因子受体研制的人源化单克隆抗体已被证实对靶向肿瘤治疗和患者管理颇具价值。本书综述了最新进展，提供与形态发生和发病相关信号传导过程的视角，重点阐述了如何使用信号级联元件作为治疗靶点。
- 英文简介：
-
Recent years have seen a considerable emphasis on growth factors and the elucidation of their mode of function, which has led to the recognition that growth factors, their receptors as well as downstream elements of signalling associated with their function might be potential targets in therapeutic management of human diseases. Humanised monoclonal antibodies raised against growth factor receptors have proved to be valuable for targeted cancer treatment and in patient management.
This book reviews the latest developments providing insights into the signalling processes involved in morphogenesis and pathogenesis with emphasis on using the elements of the signalling cascades as targets for therapeutic deployment.
