发生自然灾害后老年女性移除长期宫内节育器后的生育力

Department of Obstetrics and Gynecology, West China Second University Hospital of Sichuan University, No. 20, Renmin Nan Lu, Chengdu, Sichuan 610041, China

Background In order to evaluate the effect of long-term intrauterine device (IUD) use on female fertility, we interviewed 2301 women who lost children in the 2008 Wenchuan earthquake in China, which prompted IUD removal. Study Design A clinical retrospective survey. Result Five hundred and twenty-four women were lost to follow-up, and data from the remaining 1770 women were analyzed. The completed questionnaires revealed that 80.11% (1418/1770) became pregnant following IUD removal and about 88% (1256) of whom conceived within 1 year. Among women with different durations of IUD use, pregnancy rates and miscarriage rates were as follows: < 5 years, 89.77% and 4.27%; 6-10 years, 81.10% and 10.19%; and > 10 years, 75.20% and 12.98%, respectively. Age, duration of IUD use, a history of a previous miscarriage and abnormal menstruation before the earthquake were independently associated with reduced fertility, but a higher gravidity pre-earthquake was associated with a higher conception rate. Conclusion Long-term IUD use in older women had a high rate of pregnancy after removal of IUD, but with an increased risk of fertility problems. © 2013 Elsevier Inc.

Huang, W.; Department of Obstetrics and Gynecology, West China Second University Hospital of Sichuan University, No. 20, Renmin Nan Lu, Chengdu, Sichuan 610041, China; email:weihuang64@163.com