Clinical Infectious Diseases
(CLIN INFECT DIS) 《临床传染病》

2015年影响因子
8.736
《临床传染病》是在传染病领域具有广泛的国际读者的领先杂志。该杂志发表实践者和研究者感兴趣的主题的文章。主题范围从感染学的临床描述,公共卫生,微生物学和免疫预防感染,对当前的和新的治疗方法的评价,促进诊断和治疗的最佳做法。
- 2014-07-02•SSTI指南强调诊断技能和谨慎治疗
- 2013-08-27•氟喹诺酮类药物与严重血糖紊乱有关
- 2013-06-04•H7N9 病毒并非源于韩国
- 2012-12-31•Peg干扰素加利巴韦林对儿童亦安全有效
- 2012-09-06•通过对结核风险较低的HIV感染患者进行复查以识别出QuantiFERON-TB Gold In-Tube法的假阳性结果
- 2012-07-12•母亲产后接种破伤风、白喉毒素、无细胞百日咳疫苗对婴儿百日咳感染的影响
- 2012-05-31•无意间吞下弓形虫卵囊导致先天性弓形虫病并引起流行
- 2012-03-16•一个大型教学医院系统中的粘菌素相关性肾毒性的发生率和危险因素
- 2011-10-18•美国HIV感染的流行病学:对于医疗可及性的启示
- 2011-10-18•对隔离可疑肺结核住院患者的临床预测规则的评估
- 2013-07-01•了解医院内抗生素处方决定因素:处方礼节的作用
- 2013-07-01•丙肝病毒相关肝硬化患者中持续病毒应答后肝细胞癌风险长期持续存在
- 2013-07-01•西芹丁导致的医院获得性李斯特病爆发——德克萨斯,2010
- 2013-07-01•密切监测乙型肝炎表面抗原水平可帮助澄清Peginterferon治疗中的发作和预测治疗反应
- 2013-07-01•5项婴儿奈韦拉平预防乳汁HIV传播随机试验汇总数据分析
- 2013-07-01•突然猝死婴儿肺部近乎普遍的肺囊虫病和黏膜中相关增加
- 2015-05-12•撒哈拉沙漠以南非洲的一个大型中心医院中3周到2岁儿童中β疱疹病毒DNA血症的患病率和危险因素
- 2014-11-10•中国南方禽业工人和一般人群中的甲型(H7N9)禽流感病毒血清阳性率:一项纵向研究
- 2014-11-10•中国2013年甲型(H7N9)流感的危险因素
- 2014-02-07•甲型和乙型流感的住院成人患者的大剂量奥司他韦治疗前瞻性干预研究
- 2014-01-26•在中国伴血小板减少综合征的重度发热住院患者利巴韦林治疗的病死率及效果
- 2014-01-26•甲型(H7N9)禽流感导致的致命感染的临床、病毒学及组织病理学的临床表现
最新一期
NEWS
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IN THE LITERATURE
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CDC SECTION
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ARTICLES AND COMMENTARIES
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Clostridium difficile infection (CDI) is associated with increased mortality, prolonged hospitalization, and higher costs among a multicenter cohort of hospitalized children matched by important demographic and clinical characteristics. The impact of CDI is most significant among children with hospital-onset disease.
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Using a large, pediatric active surveillance network throughout the United States, both licensed and concurrently used rotavirus vaccines significantly protected against medically attended rotavirus gastroenteritis. Vaccine performance appeared to neither diminish over time, nor differ by predominant circulating rotavirus strain, including G12P[8].
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We performed a meta-analysis of prospective studies to compare microbiologic failure, relapse, and acquired drug resistance in tuberculosis patients on directly observed versus self-administered therapy. Directly administered therapy was no better than self-administered therapy.
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The clinical manifestation and disease progression of Mycobacterium abscessusand Mycobacterium massiliense lung disease are variable. This study provides evidence that the clinical isolates of M. abscessus and M. massiliense with specific genotypes are associated with disease phenotype and progression.
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To investigate the risk of Plasmodium falciparum infection in a cohort of naturally exposed individuals, we assessed the time to first P. falciparum infection by polymerase chain reaction analysis of dried blood spots and found no age-related differences in infection risk.
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A cold-mist humidifier in a nursery caused the first outbreak of nosocomial Legionellosis in term neonates. Legionella pneumophila serogroups 3 and 1 infected 28% of exposed neonates, causing severe pneumonia or milder atypical symptoms, conferring a 33% overall mortality.
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Highly increased immunoglobulin G anticardiolipin levels at acute Q fever diagnosis are predictive of progression to endocarditis.
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Outbreaks of bacterial species occur for the majority of bacteria commonly identified in the intensive care unit. This study provides evidence for frequent temporal clustering of resistance outbreaks consistent with interspecies transmission of resistance elements.
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In the United States, incident hepatitis C among men who have sex with men has been ongoing since at least 1984. Risk factors included unprotected receptive anal intercourse with multiple partners, HIV infection, and lower CD4 T-cell count among HIV-infected men.
INVITED ARTICLES
HEALTHCARE EPIDEMIOLOGY
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Electronic surveillance of healthcare-associated infections can increase efficiency and reliability of surveillance. Adoption of electronic systems based on multivariable regression models uses available data to their full potential to generate much-needed high-quality infection rates.
IMMUNOCOMPROMISED HOSTS
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Response to systemic antifungal therapy alone remains disproportionately less satisfactory in immunosuppressed transplant and oncology patients. Antifungal immunotherapy is appealing; however, before routine clinical use is recommended, well-designed prospective comparative clinical trials are urgently needed.
HIV/AIDS
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We present a retrospective series of CD8 encephalitis in 14 human immunodeficiency virus (HIV)–infected patients receiving combined antiretroviral therapy with very specific pathological and radiological criteria. This new HIV neurological complication, rare but severe, could be cured by glucocorticosteroids.
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We show in human immunodeficiency virus–positive persons that the coronary artery disease effect of an unfavorable genetic background is comparable to previous studies in the general population, and comparable in size to traditional risk factors and antiretroviral regimens known to increase cardiovascular risk.
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Global progress toward universal human immunodeficiency virus (HIV) testing remains slow. Interest in HIV self-testing is high and may increase knowledge of HIV status; however, empirical research on selftesting is limited, resulting in lack of evidence on which to base policy recommendations.
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A 52-week supplementation with the immunomodulatory nutritional product NR100157 resulted in a beneficial 40-cell/µL difference in human immunodeficiency virus–infected patients not on antiretroviral therapy. In a pilot study, reduced CD4+CD25+ activation was observed. This inversely correlated with CD4+ T-cell count.
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We conducted a retrospective study of cytomegalovirus viremia in Thai human immunodeficiency virus patients starting combination antiretroviral therapy with CD4 counts <200 cells/mm3. Cytomegalovirus (CMV) viremia was present in 26.3% of patients, and CMV DNA >500 copies/mL was associated with increased mortality.
CORRESPONDENCE
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ERRATA
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ELECTRONIC ARTICLES
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For the first time, cases from an outbreak of acute schistosomiasis are compared to controls. Five subjects (10%) had severe manifestations of schistosomiasis. Physicians should consider that an epidemic of schistosomiasis might emerge in a nonendemic area.
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Chagas disease–associated cardiomyopathy is clinically similar to other causes of cardiomyopathy and, therefore, the diagnosis can be easily overlooked. We found a 13% point prevalence of Chagas disease in a sample of New York City immigrants with dilated cardiomyopathy.
COVER/STANDING MATERIAL
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