Current Opinion in Immunology
(CURR OPIN IMMUNOL) 《免疫学当前观点》
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目录导读
Published 2013年6月,Volume 25,Issue 3
最新一期
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Page i
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ContentsPage iii
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Lymphocyte activation and effector functions
Edited by Axel Kallies and Bernard Malissen
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New insights into lymphocyte activation and differentiationPages 297-299 Axel Kallies, Bernard Malissen
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Controversy and consensus regarding myosin II function at the immunological synapseReview ArticlePages 300-306 John A Hammer III, Janis K Burkhardt
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Super-resolution microscopy of the immunological synapseReview ArticlePages 307-312 Jérémie Rossy, Sophie V Pageon, Daniel M Davis, Katharina Gaus
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Phosphatase regulation of immunoreceptor signaling in T cells, B cells and mast cellsReview ArticlePages 313-320 Yacine Bounab, Andrew Getahun, John C Cambier, Marc Daëron
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Transcriptional regulation of effector and memory CD8+ T cell fatesReview ArticlePages 321-328 James ED Thaventhiran, Douglas T Fearon, Luca Gattinoni
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Distinct resident and recirculating memory T cell subsets in non-lymphoid tissuesReview ArticlePages 329-333 Francis R Carbone, Laura K Mackay, William R Heath, Thomas Gebhardt
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Multiple players in mouse B cell memoryReview ArticlePages 334-338 Jean-Claude Weill, Simon Le Gallou, Yi Hao, Claude-Agnès Reynaud
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New effector functions and regulatory mechanisms of BCL6 in normal and malignant lymphocytesReview ArticlePages 339-346 Karen L Bunting, Ari M Melnick
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mTOR and lymphocyte metabolismReview ArticlePages 347-355 Hu Zeng, Hongbo Chi
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Vaccines
Edited by Irina Caminschi and Andrew M Lew
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VaccinesPages 356-358 Irina Caminschi, Andrew M Lew
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Innate and adaptive effects of inflammasomes on T cell responsesReview ArticlePages 359-365 Catherine Dostert, Kristina Ludigs, Greta Guarda
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Dynamic regulation of Bcl6 in follicular helper CD4 T (Tfh) cellsReview ArticlePages 366-372 Youn Soo Choi, Jessica A Yang, Shane Crotty
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Th17 cell based vaccines in mucosal immunityReview ArticlePages 373-380 Pawan Kumar, Kong Chen, Jay K Kolls
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Manipulating the PD-1 pathway to improve immunityReview ArticlePages 381-388 Alice O Kamphorst, Rafi Ahmed
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Dendritic cell-based nanovaccines for cancer immunotherapyReview ArticlePages 389-395 Leonie E Paulis, Subhra Mandal, Martin Kreutz, Carl G Figdor
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Graphical abstract
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Human dendritic cell subsets in vaccinationReview ArticlePages 396-402 Karolina Palucka, Jacques Banchereau
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Human immune responses and potential for vaccine assessment in humanized miceReview ArticlePages 403-409 Ramesh Akkina
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Vaccine against autoimmune disease: antigen-specific immunotherapyReview ArticlePages 410-417 Robert P Anderson, Bana Jabri
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Highlights
► Epitope hierarchies for pathogenic T cells enable ASIT/ESIT design and monitoring. ► Epitope-specific immunotherapy (ESIT) utilizes immunodominant peptides. ► Dose, route and regimen influence the immunological outcomes of ASIT. ► Monitoring T cell responses in fresh blood are essential for clinical development. ► Celiac disease provides a unique opportunity for the development of ESIT.
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Vaccine against autoimmune disease: can helminths or their products provide a therapy?Review ArticlePages 418-423 Paola Zaccone, Anne Cooke
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Highlights
► Lack of exposure to parasite infections contributes to increased incidence of autoimmune diseases. ► Parasites influence both innate and adaptive arms of the immune response to modulate inflammation. ► Parasites can inhibit onset of experimental autoimmune and allergic conditions. ► Epidemiology and clinical trials support therapeutic use of helminths to dampen inflammation. ► Parasite products can modulate the immune response and aid development of novel therapeutics.
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