JOURNAL OF PATHOLOGY
(J PATHOL) 《病理学杂志》

Deciphering the epigenetic network in colorectal cancer (pages 1–3)

Gemma Domínguez

Article first published online: 17 DEC 2012 | DOI: 10.1002/path.4094

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Stem cell research points the way to the cell of origin for intracranial germ cell tumours (pages 4–11)

Chris Tan and Paul J Scotting

Article first published online: 8 NOV 2012 | DOI: 10.1002/path.4098

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SP1 mediates the link between methylation of the tumour suppressor miR-149 and outcome in colorectal cancer (pages 12–24)

Feng Wang, Yan-Lei Ma, Peng Zhang, Tong-Yi Shen, Chen-Zhang Shi, Yong-Zhi Yang, Mary-Pat Moyer, Hui-Zhen Zhang, Hong-Qi Chen, Yong Liang and Huan-Long Qin

Article first published online: 17 DEC 2012 | DOI: 10.1002/path.4078

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Physical and chemical microenvironmental cues orthogonally control the degree and duration of fibrosis-associated epithelial-to-mesenchymal transitions (pages 25–35)

Ashley C Brown, Vincent F Fiore, Todd A Sulchek and Thomas H Barker

Article first published online: 17 DEC 2012 | DOI: 10.1002/path.4114

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Sphingosine-1-phosphate activates chemokine-promoted myeloma cell adhesion and migration involving α4β1 integrin function (pages 36–48)

David García-Bernal, Javier Redondo-Muñoz, Ana Dios-Esponera, Raphaël Chèvre, Elvira Bailón, Mercedes Garayoa, Nohemí Arellano-Sánchez, Norma C Gutierrez, Andrés Hidalgo, Angeles García-Pardo and Joaquin Teixidó

Article first published online: 17 DEC 2012 | DOI: 10.1002/path.4066

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Synaptic defects in type I spinal muscular atrophy in human development (pages 49–61)

Rebeca Martínez-Hernández, Sara Bernal, Eva Also-Rallo, Laura Alías, MaJesús Barceló, Marta Hereu, Josep E Esquerda and Eduardo F Tizzano

Article first published online: 17 DEC 2012 | DOI: 10.1002/path.4080

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Protocadherin 17 acts as a tumour suppressor inducing tumour cell apoptosis and autophagy, and is frequently methylated in gastric and colorectal cancers (pages 62–73)

Xiaotong Hu, Xinbing Sui, Lili Li, Xuefeng Huang, Rong Rong, Xianwei Su, Qinglan Shi, Lijuan Mo, Xingsheng Shu, Yeye Kuang, Qian Tao and Chao He

Article first published online: 17 DEC 2012 | DOI: 10.1002/path.4093

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Cigarette smoke disrupts the integrity of airway adherens junctions through the aberrant interaction of p120-catenin with the cytoplasmic tail of MUC1 (pages 74–86)

Lili Zhang, Marianne Gallup, Lorna Zlock, Carol Basbaum, Walter E. Finkbeiner and Nancy A. McNamara

Article first published online: 28 SEP 2012 | DOI: 10.1002/path.4070

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Pentraxin 3 (PTX3) inhibits plasma cell/stromal cell cross-talk in the bone marrow of multiple myeloma patients (pages 87–98)

Antonio Basile, Michele Moschetta, Paolo Ditonno, Roberto Ria, Ilaria Marech, Annunziata De Luisi, Simona Berardi, Maria Antonia Frassanito, Emanuele Angelucci, Daniele Derudas, Giorgina Specchia, Paola Curci, Vincenzo Pavone, Bernardo Rossini, Domenico Ribatti, Barbara Bottazzi, Alberto Mantovani, Marco Presta, Franco Dammacco and Angelo Vacca

Article first published online: 1 OCT 2012 | DOI: 10.1002/path.4081

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MLH1-silenced and non-silenced subgroups of hypermutated colorectal carcinomas have distinct mutational landscapes (pages 99–110)

Lawrence A Donehower, Chad J Creighton, Nikolaus Schultz, Eve Shinbrot, Kyle Chang, Preethi H Gunaratne, Donna Muzny, Chris Sander, Stanley R Hamilton, Richard A Gibbs and David Wheeler

Article first published online: 17 DEC 2012 | DOI: 10.1002/path.4087

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Molecular characterization of mucinous ovarian tumours supports a stratified treatment approach with HER2 targeting in 19% of carcinomas (pages 111–120)

Michael S Anglesio, Stefan Kommoss, Mary C Tolcher, Blaise Clarke, Laura Galletta, Henry Porter, Sambasivarao Damaraju, Sian Fereday, Boris J Winterhoff, Steve E Kalloger, Janine Senz, Winnie Yang, Helen Steed, Ghassan Allo, Sarah Ferguson, Patricia Shaw, Attila Teoman, Joaquin J Garcia, John K Schoolmeester, Jamie Bakkum-Gamez, Anna V Tinker, David D Bowtell, David G Huntsman, C Blake Gilks and Jessica N McAlpine

Article first published online: 17 DEC 2012 | DOI: 10.1002/path.4088

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Nod2 deficiency impairs inflammatory and epithelial aspects of the cutaneous wound-healing response (pages 121–131)

Laura Campbell, Helen Williams, Rachel A Crompton, Sheena M Cruickshank and Matthew J Hardman

Article first published online: 17 DEC 2012 | DOI: 10.1002/path.4095

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Oncogene-dependent control of miRNA biogenesis and metastatic progression in a model of undifferentiated pleomorphic sarcoma (pages 132–140)

Jeffrey K Mito, Hooney D Min, Yan Ma, Jessica E Carter, Brian E Brigman, Leslie Dodd, David Dankort, Martin McMahon and David G Kirsch

Article first published online: 20 NOV 2012 | DOI: 10.1002/path.4099

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