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(OPHTHALMOLOGY) 《眼科学》

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眼科学
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《眼科学》,美国眼科学会的官方刊物,发表原始,同行评审的研究报告,涉及基本的科学调查和临床研究。包括新的诊断和手术技术,治疗方法,仪器的更新,最新的药物发现,临床试验研究结果。
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Published 2012年7月,Volume 119,Issue 7

最新一期

Article Title Author(s) Pages
Editorial Board

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A2
This Issue at a Glance
Article Title Author(s) Pages
This Issue At A Glance

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Lori Baker Schena, John Kerrison A7
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A Simple Vista en Este Número

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Lori Baker Schena, John Kerrison e1-e2
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This Issue At A Glance

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由Lori Baker Schena, 并且John Kerrison e3
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Contents

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A11
Editorial
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Taking TASS to Task

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John D. Gottsch, Oliver D. Schein 1295-1296
Original Articles
Translational Science Review
Article Title Author(s) Pages
The Food and Drug Administration's Proactive Toxic Anterior Segment Syndrome Program

14 May 2012

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Malvina B. Eydelman, Michelle E. Tarver, Don Calogero, Shelley Y. Buchen, et al. 1297-1302
Keratoplasty for Corneal Endothelial Disease, 2001–2009

17 April 2012

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Roni M. Shtein, Duna Raoof-Daneshvar, Hsien-Chang Lin, Alan Sugar,et al. 1303-1310
Indications, Outcomes, and Risk Factors for Failure in Tectonic Keratoplasty

30 April 2012

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Marcus Ang, Jodhbir S. Mehta, Chelvin C.A. Sng, Hla Myint Htoon,et al. 1311-1319
Association of Single Nucleotide Polymorphisms of Interleukins-1β, -6, and -12B with Contact Lens Keratitis Susceptibility and Severity

12 April 2012

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Nicole A. Carnt, Mark D.P. Willcox, Scott Hau, Linda L. Garthwaite, et al. 1320-1327
Tofacitinib (CP-690,550), a Janus Kinase Inhibitor for Dry Eye Disease: Results from a Phase 1/2 Trial

23 April 2012

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Shiao Hui (Melissa) Liew, Kelly K. Nichols, Karen J. Klamerus, Jim Z. Li, et al. 1328-1335
Ocular Trauma Score: A Useful Predictor of Visual Outcome at Six Weeks in Patients with Traumatic Cataract

28 March 2012

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Mehul A. Shah, Shreya M. Shah, Adway Applewar, Chintan Patel, et al. 1336-1341
Regional Variations and Trends in the Prevalence of Diagnosed Glaucoma in the Medicare Population

04 April 2012

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Sandra D. Cassard, Harry A. Quigley, Emily W. Gower, David S. Friedman, et al. 1342-1351
Fear of Falling and Visual Field Loss from Glaucoma

04 April 2012

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Pradeep Y. Ramulu, Suzanne W. van Landingham, Robert W. Massof, Emilie S. Chan, et al. 1352-1358
Reversal of Lamina Cribrosa Displacement and Thickness after Trabeculectomy in Glaucoma

30 March 2012

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Eun Ji Lee, Tae-Woo Kim, Robert N. Weinreb 1359-1366
The Development of a Decision Analytic Model of Changes in Mean Deviation in People with Glaucoma: The COA Model

26 April 2012

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Steven M. Kymes, Dennis L. Lambert, Paul P. Lee, David C. Musch, et al. 1367-1374
Visual Symptoms and Retinal Straylight after Laser Peripheral Iridotomy: The Zhongshan Angle-Closure Prevention Trial

15 March 2012

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Nathan Congdon, Xixi Yan, David S. Friedman, Paul J. Foster, et al. 1375-1382
Changes in Anterior Segment Morphology after Laser Peripheral Iridotomy: An Anterior Segment Optical Coherence Tomography Study

12 March 2012

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Alicia C. How, Mani Baskaran, Rajesh S. Kumar, Mingguang He, et al. 1383-1387
Ranibizumab and Bevacizumab for Treatment of Neovascular Age-related Macular Degeneration: Two-Year Results

02 May 2012

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Comparison of Age-related Macular Degeneration Treatments Trials (CATT) Research Group, Daniel F. Martin, Maureen G. Maguire, Stuart L. Fine, et al. 1388-1398
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Ranibizumab versus Bevacizumab to Treat Neovascular Age-related Macular Degeneration: One-Year Findings from the IVAN Randomized Trial

11 May 2012

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The IVAN Study Investigators, Usha Chakravarthy, Simon P. Harding, Chris A. Rogers, et al. 1399-1411
Hyporeflective Wedge-Shaped Band in Geographic Atrophy Secondary to Age-related Macular Degeneration: An Underreported Finding

22 March 2012

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Jordi Monés, Marc Biarnés, Fabio Trindade 1412-1419
Changes in Antibiotic Resistance Patterns of Conjunctival Flora Due to Repeated Use of Topical Antibiotics after Intravitreal Injection

14 March 2012

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Eugene Milder, James Vander, Chirag Shah, Sunir Garg 1420-1424
Macular Epiretinal Brachytherapy in Treated Age-related Macular Degeneration: MERITAGE Study: Twelve-Month Safety and Efficacy Results

01 April 2012

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Pravin U. Dugel, Robert Petrarca, Michael Bennett, Adiel Barak, et al. 1425-1431
Risk Factors for Conversion to Neovascular Age-related Macular Degeneration Based on Longitudinal Morphologic and Visual Acuity Data

02 May 2012

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Thomas R. Friberg, Richard A. Bilonick, Peter M. Brennen 1432-1437
Correlation between Length of Foveal Cone Outer Segment Tips Line Defect and Visual Acuity after Macular Hole Closure

15 March 2012

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Yuji Itoh, Makoto Inoue, Tosho Rii, Tomoyuki Hiraoka, et al. 1438-1446
A Novel Noninvasive Detection Method for Retinal Nonperfusion Using Confocal Red-free Imaging

04 April 2012

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Yong Un Shin, Byung Ro Lee, Sungmin Kim, Won June Lee 1447-1454
Clinical Manifestations of Human Immunodeficiency Virus-Induced Uveitis

30 April 2012

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Paradee Kunavisarut, Wasna Sirirungsi, Kessara Pathanapitoon, Aniki Rothova 1455-1459
Clinical Features and Presentation of Infectious Scleritis from Herpes Viruses: A Report of 35 Cases

29 March 2012

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Luis Alonso Gonzalez-Gonzalez, Nicolas Molina-Prat, Priyanka Doctor, Joseph Tauber, et al. 1460-1464
Ocular Whipple's Disease: Therapeutic Strategy and Long-Term Follow-Up

14 March 2012

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Valérie Touitou, Florence Fenollar, Nathalie Cassoux, Helene Merle-Beral, et al. 1465-1469
Outcome, Pathologic Findings, and Compliance in Orbital Retinoblastoma (International Retinoblastoma Staging System Stage III) Treated with Neoadjuvant Chemotherapy: A Prospective Study

29 March 2012

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Venkatraman Radhakrishnan, Seema Kashyap, Neelam Pushker, Sanjay Sharma,et al. 1470-1477
Annual Changes in Refractive Errors and Ocular Components before and after the Onset of Myopia in Chinese Children

11 May 2012

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Fan Xiang, Mingguang He, Ian G. Morgan 1478-1484
Congenital Ectropion Uvea and Mechanisms of Glaucoma in Neurofibromatosis Type 1: New Insights

04 April 2012

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Deepak P. Edward, Jose Morales, Rachida A. Bouhenni, Jayaprakash Patil, et al. 1485-1494
Online-only Articles
Article Title Author(s) Pages
Rabbit Ocular Reactivity to Bacterial Endotoxin Contained in Aqueous Solution and Ophthalmic Viscosurgical Devices

14 May 2012

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Shelley Y. Buchen, Don Calogero, Gene Hilmantel, Malvina B. Eydelman e4-e10
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Detecting Endotoxin Contamination of Ophthalmic Viscosurgical Devices: Intracameral versus Intravitreal Assays in Rabbits

14 May 2012

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Shelley Y. Buchen, Don Calogero, Gene Hilmantel, Malvina B. Eydelman e11-e18
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Rabbit Intraocular Reactivity to Endotoxin Measured by Slit-Lamp Biomicroscopy and Laser Flare Photometry

14 May 2012

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Robert B. Nussenblatt, Don Calogero, Shelley Y. Buchen, Henry A. Leder, et al. e19-e23
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Evaluation of Intraocular Reactivity to Organic Contaminants of Ophthalmic Devices in a Rabbit Model

14 May 2012

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Shelley Y. Buchen, Don Calogero, Michelle E. Tarver, Gene Hilmantel, et al. e24-e29
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An Investigation of Enzymatic Detergents as a Potential Cause of Toxic Anterior Segment Syndrome

11 May 2012

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Henry A. Leder, Margot Goodkin, Shelley Y. Buchen, Don Calogero, et al. e30-e35
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Evaluation of Intraocular Reactivity to Metallic and Ethylene Oxide Contaminants of Medical Devices in a Rabbit Model

14 May 2012

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Don Calogero, Shelley Y. Buchen, Michelle E. Tarver, Gene Hilmantel, et al. e36-e42
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Immunomodulatory Effect of the Topical Ophthalmic Janus Kinase Inhibitor Tofacitinib (CP-690,550) in Patients with Dry Eye Disease

18 May 2012

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Jing-Feng Huang, Rolla Yafawi, Min Zhang, Michael McDowell, et al. e43-e50
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Letters to the Editor
Research Correspondence
Article Title Author(s) Pages
New Color Iris Implants

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Rupa D. Shah, J. Bradley Randleman 1495-1495.e2
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Positron Emission Tomography

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Angelina Cistaro, Natale Quartuccio, Sara Vesco, Marco Pagani, et al. 1496-1497.e1
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Choroidal Thickness After Scleral Buckling

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Masahiro Miura, Go Arimoto, Rintaro Tsukahara, Rei Nemoto, et al. 1497-1498
Adaptive Optics Photoreceptor Imaging

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Marco Lombardo, Giuseppe Lombardo, Pietro Ducoli, Sebastiano Serrao 1498-1498.e2
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General Correspondence
Article Title Author(s) Pages
Descemet's Stripping Automated Endothelial Keratoplasty

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Sunita Chaurasia, Muralidhar Ramappa, Harsha Laxmana Rao, Piyush Bansal 1498-1499
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Jennifer Y. Li, Mark A. Terry, Jeffrey Goshe, David Davis-Boozer 1499
Pseudoexfoliation

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Hugh R. Taylor 1499-1500
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Louis R. Pasquale, Jae Hee Kang, Stephanie Loomis, Janey L. Wiggs, et al. 1500
Myopia and Glaucoma

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Harry H. Mark 1500-1501.e1
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Tae-Woo Kim, Martha Kim, Robert N. Weinreb 1501
Drusen Volume as a Study Endpoint

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Maureen G. Maguire 1501-1502
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Zohar Yehoshua, Fenghua Wang, Philip J. Rosenfeld, Fernando M. Penha, et al. 1502
Cat Scratch Disease

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Clare L. Fraser, Susan Sanchez, Nancy J. Newman, Valérie Biousse 1502-1503
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Sulene L. Chi, Eric Eggenberger, Rod Foroozan, Karl Golnik, et al. 1503
Intraocular Lenses in Children

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Sumit Monga, Muralidhar Ramappa, Ramesh Kekunnaya, Sunita Chaurasia, et al. 1503-1504
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David A. Plager, Michael J. Lynn, M. Edward Wilson, Edward G. Buckley, et al. 1504-1505
Pediatric Posterior Scleritis

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Genie M. Bang, Michael C. Brodsky 1505-1505.e1
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Chui Ming Gemmy Cheung, Soon-Phaik Chee 1505
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  • 2015-04-01 14:04  发表郭超伟   北京协和医院  肿瘤科

    《眼科学杂志》于1978年创刊,是美国眼科学会的官方刊物,由Elsevier出版社每月出版,近5年的平均影响因子为6.195分,2013年影响因子为6.170,是眼科领域同类期刊中影响因子排名第二的杂志。该杂志内容偏向临床,对实验设计的创新性、统计学方法的科学性及英文表达的准确性要求较高,主要面对眼科临床医师,其文章类型包括论著、AAO会议文章、读者来信(Correspondence)、主编约稿(Editorial)、荟萃分析以及转化医学综述。杂志稿件由国际专家严格同行评议,其编委会由近40名来自世界各地的著名眼科学专家、统计学专家及流行病学专家组成,主编为曾任Mayo Clinic首席执行官的著名眼整形专家George B. Bartley教授,值得一提的是该杂志亚洲区编委是来自中国广州中山大学中山眼科中心的青光眼专家何明光教授。 2014年8月刊中登出了一篇美国加州大学圣地亚哥分校汉密尔顿青光眼中心关于黄斑区视网膜神经节细胞(RCG)计数预测青光眼视神经损伤的研究。青光眼以RGC的功能障碍和损失为特点,应用OCT可以获得黄斑区结构的客观测量。本研究旨在评价青光眼患者黄斑区节细胞内丛状层(mGCIPL)厚度和RGC之间的关系,并比较mGCIPL厚度和预计RGC细胞数量区分健康眼和青光眼的能力,结果发现了黄斑区RGC计数和mGCIPL厚度之间的强相关性,以及黄斑区RGC计数能够更加出色的评估青光眼损伤,这提供了青光眼专家早期发现并定量评估患者视功能损伤程度的依据。 2014年9月刊中发表了一篇北京大学人民医院眼科黎晓新教授团队有关康柏西普治疗新生血管性年龄相关性黄斑变性安全性和有效性的文章,即AURORA研究2期临床的结果。康柏西普是我国独立自主研发的拥有全球知识产权的单克隆抗体新药,其临床实验对我国新药研发具有重大的开创性意义。本研究共纳入122名患者,1:1随机分组分别接受0.5mg和2.0mg康柏西普每月一次眼内注射连续3月,随后随机以原有剂量接受每月一次注射或仅在必要时接受注射,观察12个月,结果发现所有剂量组患者的最佳矫正视力均较基线水平显著提高且耐受良好,不同剂量或不同治疗方案之间并无显著差异,说明康柏西普治疗新生血管性年龄相关性黄斑变性具有非常好的前景。当然,还需要3期临床实验的进一步验证。 2014年10月刊中发表一篇有关地塞米松玻璃体腔植入剂治疗糖尿病黄斑水肿(DME)的随机、安慰剂对照、为期三年的临床实验结果。该地塞米松玻璃体腔植入剂(Ozurdex)是一种可生物降解的植入剂,它被放置于眼睛后段的玻璃体腔内,被称为Novadur的专有固体聚合物长效系统的释放地塞米松注射液,是目前治疗黄斑水肿的新型药物类型,其适应症方面的临床实验结果具有重要的指导意义。该临床实验是由来自美国加州大学洛杉矶分校的David S. Boyer教授团队进行,其研究结果发现0.7mg和0.35mg的Ozurdex在三年内分别平均注射4.1和4.4次,均至少提高患者视力15个字母,与安慰剂组相比均具有显著差异,且未发生严重不良事件,说明Ozurdex治疗DME安全有效,有望在不久的将来应用于临床,造福更多黄斑水肿患者。 2014年11月刊中登出了我国著名葡萄膜炎专家杨培增教授团队有关原田小柳病(VKH)和白塞病(BD)遗传学方面的研究成果。原田小柳病和白塞病均是好发于东亚地区的葡萄膜炎疾病,在我国发病率较高,了解其发病的遗传学机制具有重要的临床意义。杨培增教授是我国葡萄膜炎领域的领军人物,拥有极其丰富的临床病例资料,其领导的团队研究结果指出IL17F和IL23A的高拷贝数量与BD和VKH发病有关,而IL17F蛋白表达的增强 以及外周血单核细胞的增殖与IL17F高拷贝数量有关。 2014年11月刊上还登出了一篇著名角膜病专家Jonathan H. Lass教授团队关于供体糖尿病是否影响角膜移植成功率的文章。随着全球糖尿病患者的增加,器官移植供体人群也发生变化,供体糖尿病病史是否影响器官在受体中的状态成为我们重点关心的问题。该研究为一项多中心、前瞻性、双盲、对照的临床研究,纳入美国80个临床中心的1090例穿透性角膜移植患者,关于供体和受体的糖尿病病情从医疗记录中获得,主要观察结果为移植失败时间和角膜内皮计数(ECD)。结果发现供体糖尿病病史与移植失败率、基线ECD、术后10年ECD和10年来ECD的变化均无显著关联。该研究并未发现供体糖尿病病史与穿透性角膜移植预后的关系。然而,该研究中对供体的糖尿病病情评估仅基于病历数据,是不精确的。因此,进一步探索供体糖尿病对角膜移植术后角膜内皮的影响还需要更多、更精确的评估糖尿病及其并发症状态的研究。 《眼科学》(Ophthalmology)杂志主要发表国际性多中心临床实验结果、具有开创意义的临床研究文章及大规模的流行病学研究成果,主要面向眼科专业人员,是眼科领域的权威杂志。 来源:医科院图书馆《国外医学新书评介》  


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