爱思唯尔期刊精选全文

		Translational Research
		中文标题: α-球蛋白基因变异和缺失的新的快速检测方法
		英文标题: Novel technique for rapid detection of α-globin gene mutations and deletions
		作者: Jingzhong Liu, Xingyuan Jia, Ning Tang, Xu Zhang, ...
		全文: Populations in Southeast Asia and South China have high frequencies of α-thalassemia caused by α-globin gene mutations and/or deletions. This study was designed to find an efficient and simple d...

		American Journal of Medicine
		中文标题: 心衰病人的心房颤动：系统回顾
		英文标题: Atrial Fibrillation in Heart Failure: A Comprehensive Review
		作者: Prakash C. Deedwania MD, and Joel A. Lardizabal MD
		全文: Chronic heart failure and atrial fibrillation are 2 major disorders that are closely linked. Their coexistence is associated with adverse prognosis. Both share several common predisposing conditio...

		Gastroenterology Clinics of North America
		中文标题: 综述：与肥胖相关的胃肠道症状和疾病
		英文标题: Gastrointestinal Symptoms and Diseases Related to Obesity: An Overview
		作者: Amy E. Foxx-Orenstein DO
		全文: Obesity is a leading cause of illness and death worldwide. It is a risk factor for many common gastrointestinal symptoms and digestive disorders, including many cancers. Disruption of mechanisms tha...

		Free Radical Biology and Medicine
		中文标题: 活性氧、细胞氧化还原系统与凋亡
		英文标题: Reactive oxygen species, cellular redox systems, and apoptosis
		作者: Magdalena L. Circu and Tak Yee Aw
		全文: Reactive oxygen species (ROS) are products of normal metabolism and xenobiotic exposure, and depending on their concentration, ROS can be beneficial or harmful to cells and tissues. At physiologic...

		Free Radical Biology and Medicine
		中文标题: 糖尿病大鼠心源性蛋白中的α-烯醇酶的氧化和硝化修饰
		英文标题: Oxidative and nitrative modifications of α-enolase in cardiac proteins from diabetic rats
		作者: Naihao Lua, Yan Zhanga, Hailing Lia, and Zhonghong...
		全文: Many studies have reported that oxidative and nitrative stress might be important in the pathogenesis of diabetes. By means of immunoprecipitation analysis, α-enolase (EC 4.2.1.11, 2-phospho-d-gly...

		American Journal of Cardiology
		中文标题: 多层螺旋CT冠状动脉成像术在评估冠状动脉支架再狭窄中的作用
		英文标题: Multidetector Computed Tomography Coronary Angiography for the Assessment of Coronary In-Stent Restenosis
		作者: Daniele Andreini MD, Gianluca Pontone MD, Saima Mu...
		全文: The investigators conducted a review to evaluate the diagnostic performance of multidetector computed tomography (MDCT) for coronary stent evaluation. The prespecified inclusion criteria selecte...

		Seminars in Perinatology
		中文标题: 发育中大脑的MRI影像：最新进展的基本原理和概念
		英文标题: Basic Principles and Concepts Underlying Recent Advances in Magnetic Resonance Imaging of the Developing Brain
		作者: Ashok Panigrahy MD, Matthew Borzage MSc and Stefan...
		全文: Over the last decade, magnetic resonance (MR) imaging has become an essential tool in the evaluation of both in vivo human brain development and perinatal brain injury. Recent technology including M...

		American Journal of Obstetrics and Gynecology
		中文标题: 低出生体重、早产、小于胎龄儿的父亲因素：系统回顾
		英文标题: Paternal factors and low birthweight, preterm, and small for gestational age births: a systematic review
		作者: Prakesh S. Shah, and Knowledge Synthesis Group on ...
		全文: A systematic review of the risks of a low birthweight (LBW), preterm, and small-for-gestational-age births in relation to paternal factors was performed. Medline, Embase, Cumulative Index of Nursing...

		American Journal of Medicine
		中文标题: 门静脉血栓
		英文标题: Portal Vein Thrombosis
		作者: Sameer Parikh MD, Riddhi Shah MD and Prashant Kapo...
		全文: Portal vein thrombosis is a condition not infrequently encountered by clinicians. It results from a combination of local and systemic prothrombotic risk factors. The presentation of acute thrombos...

		Free Radical Biology and Medicine
		中文标题: 衰老的氧化应激理论进展：氧化应激在衰老或者说健康地衰老的过程中起作用吗？
		英文标题: Update on the oxidative stress theory of aging: Does oxidative stress play a role in aging or healthy aging?
		作者: Adam B. Salmon, Arlan Richardson and Viviana I. Pé...
		全文: The oxidative stress theory of aging predicts that manipulations that alter oxidative stress/damage will alter aging. The gold standard for determining whether aging is altered is life span, i.e.,...

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甲状腺功能亢进合并黄疸

王燕燕王曙

上海交通大学附属瑞金医院内分泌科

患者，女，69岁。2009年1月无明显诱因下出现乏力，当时程度较轻，未予以重视。2009年3月患者乏力症状加重，尿色逐渐加深，大便习惯改变，颜色变淡。4月18日入我院感染科治疗，诉轻度头晕、心慌，体重减轻10kg。无肝区疼痛，无发热，无腹痛、腹泻、腹胀、里急后重，无恶性、呕吐等。入院半月前于外院就诊，查肝功能：ALT 601IU/L，AST 785IU/L，TBIL 97.7umol/L，白蛋白 41g/L，甲状腺功能：游离T3 30.6pmol/L，游离T4 51.9pmol/L，心电图示快速房颤。

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