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Journal of Investigative Dermatology
(J Invest Dermatol) 《研究性皮肤病学杂志》

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研究性皮肤病学杂志
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期刊介绍

《研究性皮肤病学杂志》发表皮肤生物学和皮肤疾病所有方面的原创研究文章。主题包括生物化学、生物物理学、致癌作用、细胞调控、发育、皮肤结构、细胞外基质、遗传学、免疫学、黑色素细胞生物学、微生物学、分子与细胞生物学、病理学、生理学、药理学、光生物学、经皮吸收、临床研究、流行病学及其他基于人群的研究。

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Published 2013年1月,Volume 1,Issue 133

最新一期

EDITORIAL

The Year of Unity FREE

Barbara A Gilchrest Editor

J Invest Dermatol 133: 1-3; doi:10.1038/jid.2012.491

Clinical Snippets FREE

J Invest Dermatol 133: 4; doi:10.1038/jid.2012.452

See also: Original Article by Wagener et al.See also: Original Article by Chen et al.See also: Original Article by Kim et al.See also: Original Article by Vazquez et al.See also: Original Article by Bracher et al.

BJD Editor's Choice FREE

J Invest Dermatol 133: 5; doi:10.1038/jid.2012.453

Editors' Picks FREE

J Invest Dermatol 133: 6; doi:10.1038/jid.2012.454

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RESEARCH TECHNIQUES MADE SIMPLE

Immunofluorescence Techniques FREE

Ian D Odell and Deborah Cook

J Invest Dermatol 133: e4; doi:10.1038/jid.2012.455

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COMMENTARIES

Tuning Wnt Signals for More or Fewer Hairs FREE

Ming-Xing Lei, Cheng-Ming Chuong and Randall B Widelitz

J Invest Dermatol 133: 7-9; doi:10.1038/jid.2012.446

See also: Original Article by Myung et al.See also: Original Article by Li et al.

TGFβ1, an Epidermal Controller of Skin Dendritic Cell Homeostasis FREE

Akihiko Kitoh, Takashi Nomura and Kenji Kabashima

J Invest Dermatol 133: 9-11; doi:10.1038/jid.2012.411

See also: Original Article by Mohammed et al.

Cutaneous Pigmentation in Health and Disease: Novel and Well-Established Players FREE

Mina Yaar

J Invest Dermatol 133: 11-13; doi:10.1038/jid.2012.442

See also: Original Article by Kim et al.See also: Original Article by Dynoodt et al.

An Unexpected Role for EGF in Lymphangiogenesis-Mediated Melanoma Metastasis to Sentinel Lymph Nodes FREE

Soheil S Dadras

J Invest Dermatol 133: 14-16; doi:10.1038/jid.2012.436

See also: Original Article by Bracher et al.
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REVIEWS

The Emerging Role of IL-17 in the Pathogenesis of Psoriasis: Preclinical and Clinical Findings FREE

David A Martin, Jennifer E Towne, Gregory Kricorian, Paul Klekotka, Johann E Gudjonsson, James G Krueger and Chris B Russell

J Invest Dermatol 133: 17-26; advance online publication, June 7, 2012; doi:10.1038/jid.2012.194

Reflections on the Field of Photoimmunology FREE

Margaret L Kripke

J Invest Dermatol 133: 27-30; advance online publication, August 2, 2012; doi:10.1038/jid.2012.234

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ORIGINAL ARTICLES

APPENDAGES

Epithelial Wnt Ligand Secretion Is Required for Adult Hair Follicle Growth and Regeneration FREE

Peggy S Myung, Makoto Takeo, Mayumi Ito and Radhika P Atit

J Invest Dermatol 133: 31-41; advance online publication, July 19, 2012; doi:10.1038/jid.2012.230

See also: Commentary by Lei et al.
Adenovirus-Mediated Wnt10b Overexpression Induces Hair Follicle Regeneration FREE

Yu-Hong Li, Kun Zhang, Ke Yang, Ji-Xing Ye, Yi-Zhan Xing, Hai-Ying Guo, Fang Deng, Xiao-Hua Lian and Tian Yang

J Invest Dermatol 133: 42-48; advance online publication, July 26, 2012; doi:10.1038/jid.2012.235

See also: Commentary by Lei et al.

CELL BIOLOGY

Differential Effects of Neurofibromin Gene Dosage on Melanocyte Development FREE

Mugdha Deo, Jenny Li-Ying Huang, Helmut Fuchs, Martin Hrabe de Angelis and Catherine D Van Raamsdonk

J Invest Dermatol 133: 49-58; advance online publication, July 19, 2012; doi:10.1038/jid.2012.240

Increased Presence of Monounsaturated Fatty Acids in the Stratum Corneum of Human Skin Equivalents FREE

Varsha S Thakoersing, Jeroen van Smeden, Aat A Mulder, Rob J Vreeken, Abdoelwaheb El Ghalbzouri and Joke A Bouwstra

J Invest Dermatol 133: 59-67; advance online publication, August 16, 2012; doi:10.1038/jid.2012.262

Interferon Regulatory Factor 6 Promotes Differentiation of the Periderm by Activating Expression of Grainyhead-Like 3 FREE

Gabriel de la Garza, Jack Robert Schleiffarth, Martine Dunnwald, Anuj Mankad, Jason L Weirather, Gregory Bonde, Stephen Butcher, Tamer A Mansour, Youssef A Kousa, Cindy F Fukazawa, Douglas W Houston, J Robert Manak, Brian C Schutte, Daniel S Wagner and Robert A Cornell

J Invest Dermatol 133: 68-77; advance online publication, August 30, 2012; doi:10.1038/jid.2012.269

Aurora Kinase-A Deficiency during Skin Development Impairs Cell Division and Stratification FREE

Enrique C Torchia, Lei Zhang, Aaron J Huebner, Subrata Sen and Dennis R Roop

J Invest Dermatol 133: 78-86; advance online publication, July 26, 2012; doi:10.1038/jid.2012.249

Aryl Hydrocarbon Receptor Repressor (AhRR) Function Revisited: Repression of CYP1 Activity in Human Skin Fibroblasts Is Not Related to AhRR Expression FREE

Julia Tigges, Heike Weighardt, Sandra Wolff, Christine Götz, Irmgard Förster, Zippora Kohne, Ulrike Huebenthal, Hans F Merk, Josef Abel, Thomas Haarmann-Stemmann, Jean Krutmann and Ellen Fritsche

J Invest Dermatol 133: 87-96; advance online publication, September 6, 2012; doi:10.1038/jid.2012.259

CLINICAL RESEARCH

Incidence of Hidradenitis Suppurativa and Associated Factors: A Population-Based Study of Olmsted County, Minnesota FREE

Benjamin G Vazquez, Ali Alikhan, Amy L Weaver, David A Wetter and Mark D Davis

J Invest Dermatol 133: 97-103; advance online publication, August 30, 2012; doi:10.1038/jid.2012.255

Field Performance of the Skindex-17 Quality of Life Questionnaire: A Comparison with the Skindex-29 in a Large Sample of Dermatological Outpatients FREE

Francesca Sampogna, Alessandra Spagnoli, Cristina Di Pietro, Calogero Pagliarello, Andrea Paradisi, Stefano Tabolli and Damiano Abeni

J Invest Dermatol 133: 104-109; advance online publication, July 26, 2012; doi:10.1038/jid.2012.244

CONNECTIVE TISSUE

Discoidin Domain Receptor 2–microRNA 196a–Mediated Negative Feedback against Excess Type I Collagen Expression Is Impaired in Scleroderma Dermal Fibroblasts FREE

Katsunari Makino, Masatoshi Jinnin, Jun Aoi, Ayaka Hirano, Ikko Kajihara, Takamitsu Makino, Keisuke Sakai, Satoshi Fukushima, Yuji Inoue and Hironobu Ihn

J Invest Dermatol 133: 110-119; advance online publication, July 26, 2012; doi:10.1038/jid.2012.252

A Role for Estrogen Receptor-α and Estrogen Receptor-β in Collagen Biosynthesis in Mouse Skin FREE

Margaret Markiewicz, Sergey Znoyko, Lukasz Stawski, Angela Ghatnekar, Gary Gilkeson and Maria Trojanowska

J Invest Dermatol 133: 120-127; advance online publication, August 16, 2012; doi:10.1038/jid.2012.264

GENETICS

Linkage Analysis of Extended High-Risk Pedigrees Replicates a Cutaneous Malignant Melanoma Predisposition Locus on Chromosome 9q21 FREE

Lisa A Cannon-Albright, Craig C Teerlink, James M Farnham, Alun W Thomas, John J Zone and Sancy A Leachman

J Invest Dermatol 133: 128-134; advance online publication, September 6, 2012; doi:10.1038/jid.2012.271

IMMUNOLOGY/INFECTION

TGFβ1 Overexpression by Keratinocytes Alters Skin Dendritic Cell Homeostasis and Enhances Contact Hypersensitivity FREE

Javed Mohammed, Andrew J Gunderson, Hong-Hanh Khong, Richard D Koubek, Mark C Udey and Adam B Glick

J Invest Dermatol 133: 135-143; advance online publication, July 26, 2012; doi:10.1038/jid.2012.241

See also: Commentary by Kitoh et al.
A Peptide Derived from the Highly Conserved Protein GAPDH Is Involved in Tissue Protection by Different Antifungal Strategies and Epithelial Immunomodulation FREE

Jeanette Wagener, Josef J Schneider, Susann Baxmann, Hubert Kalbacher, Claudia Borelli, Sabine Nuding, Robert Küchler, Jan Wehkamp, Matthias D Kaeser, Daniela Mailänder-Sanchez, Christina Braunsdorf, Bernhard Hube, Lydia Schild, Wolf-Georg Forssmann, Hans-Christian Korting, Cornelia Liepke and Martin Schaller

J Invest Dermatol 133: 144-153; advance online publication, July 26, 2012; doi:10.1038/jid.2012.254

TSLP Produced by Keratinocytes Promotes Allergen Sensitization through Skin and Thereby Triggers Atopic March in Mice FREE

Juan Manuel Leyva-Castillo, Pierre Hener, Hua Jiang and Mei Li

J Invest Dermatol 133: 154-163; advance online publication, July 26, 2012; doi:10.1038/jid.2012.239

CCR6 Is Required for Epidermal Trafficking of γδ-T Cells in an IL-23-Induced Model of Psoriasiform Dermatitis FREE

Tomotaka Mabuchi, Tej Pratap Singh, Tomonori Takekoshi, Guang-fu Jia, Xuesong Wu, Mandy C Kao, Ido Weiss, Joshua M Farber and Sam T Hwang

J Invest Dermatol 133: 164-171; advance online publication, August 16, 2012; doi:10.1038/jid.2012.260

KERATINOCYTES/EPIDERMIS

Aloxe3 Knockout Mice Reveal a Function of Epidermal Lipoxygenase-3 as Hepoxilin Synthase and Its Pivotal Role in Barrier Formation FREE

Peter Krieg, Sabine Rosenberger, Silvia de Juanes, Susanne Latzko, Jin Hou, Angela Dick, Ulrich Kloz, Frank van der Hoeven, Ingrid Hausser, Irene Esposito, Manfred Rauh and Holm Schneider

J Invest Dermatol 133: 172-180; advance online publication, July 26, 2012; doi:10.1038/jid.2012.250

Keratins Mediate Localization of Hemidesmosomes and Repress Cell Motility FREE

Kristin Seltmann, Wera Roth, Cornelia Kröger, Fanny Loschke, Marcell Lederer, Stefan Hüttelmaier and Thomas M Magin

J Invest Dermatol 133: 181-190; advance online publication, August 16, 2012; doi:10.1038/jid.2012.256

MELANOCYTES/MELANOMA

Reduced WIF-1 Expression Stimulates Skin Hyperpigmentation in Patients with Melasma FREE

Ji-Young Kim, Tae-Ryong Lee and Ai-Young Lee

J Invest Dermatol 133: 191-200; advance online publication, September 6, 2012; doi:10.1038/jid.2012.270

See also: Commentary by Yaar et al.
Identification of miR-145 as a Key Regulator of the Pigmentary Process FREE

Peter Dynoodt, Pieter Mestdagh, Gert Van Peer, Jo Vandesompele, Karen Goossens, Luc J Peelman, Barbara Geusens, Reinhart M Speeckaert, Jo L W Lambert and Mireille J L Van Gele

J Invest Dermatol 133: 201-209; advance online publication, August 16, 2012; doi:10.1038/jid.2012.266

See also: Commentary by Yaar et al.
Melanoma Cell Invasiveness Is Promoted at Least in Part by the Epidermal Growth Factor–Like Repeats of Tenascin-C FREE

Jelena Grahovac, Dorothea Becker and Alan Wells

J Invest Dermatol 133: 210-220; advance online publication, September 6, 2012; doi:10.1038/jid.2012.263

CYLD Inhibits Melanoma Growth and Progression through Suppression of the JNK/AP-1 and β1-Integrin Signaling Pathways FREE

Hengning Ke, Christina K Augustine, Vineela D Gandham, Jane Y Jin, Douglas S Tyler, Steven K Akiyama, Russell P Hall and Jennifer Y Zhang

J Invest Dermatol 133: 221-229; advance online publication, July 26, 2012; doi:10.1038/jid.2012.253

Epidermal Growth Factor Facilitates Melanoma Lymph Node Metastasis by Influencing Tumor Lymphangiogenesis FREE

Andreas Bracher, Ana Soler Cardona, Stefanie Tauber, Astrid M Fink, Andreas Steiner, Hubert Pehamberger, Heide Niederleithner, Peter Petzelbauer, Marion Gröger and Robert Loewe

J Invest Dermatol 133: 230-238; advance online publication, September 6, 2012; doi:10.1038/jid.2012.272

See also: Commentary by Dadras et al.

TUMOR BIOLOGY

A Transposon-Based Analysis of Gene Mutations Related to Skin Cancer Development FREE

Rita M Quintana, Adam J Dupuy, Ana Bravo, M Llanos Casanova, Josefa P Alameda, Angustias Page, Miguel Sánchez-Viera, Angel Ramírez and Manuel Navarro

J Invest Dermatol 133: 239-248; advance online publication, July 26, 2012; doi:10.1038/jid.2012.245

Impaired Proteasome Function Activates GATA3 in T Cells and Upregulates CTLA-4: Relevance for Sézary Syndrome FREE

Heather M Gibson, Anjali Mishra, Derek V Chan, Timothy S Hake, Pierluigi Porcu and Henry K Wong

J Invest Dermatol 133: 249-257; advance online publication, September 6, 2012; doi:10.1038/jid.2012.265

WOUND HEALING

Toll-Like Receptor 4 Has an Essential Role in Early Skin Wound Healing FREE

Lin Chen, Shujuan Guo, Matthew J Ranzer and Luisa A DiPietro

J Invest Dermatol 133: 258-267; advance online publication, September 6, 2012; doi:10.1038/jid.2012.267

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LETTERS TO THE EDITOR

NGF Sensitizes Nociceptors for Cowhage- but Not Histamine-Induced Itch in Human Skin FREE

Roman R Rukwied, Maurice Main, Benjamin Weinkauf and Martin Schmelz

J Invest Dermatol 133: 268-270; advance online publication, July 26, 2012; doi:10.1038/jid.2012.242

Epidermolysis Bullosa Simplex Ogna Revisited FREE

Dimitra Kiritsi, Manuela Pigors, Iliana Tantcheva-Poor, Cordula Wessel, Meral Julia Arin, Jürgen Kohlhase, Leena Bruckner-Tuderman and Cristina Has

J Invest Dermatol 133: 270-273; advance online publication, August 2, 2012; doi:10.1038/jid.2012.248

Topical 5-Fluorouracil Elicits Regressions of BRAF Inhibitor–Induced Cutaneous Squamous Cell Carcinoma FREE

Amaya Viros, Robert Hayward, Matthew Martin, Sharona Yashar, Clarissa C Yu, Berta Sanchez-Laorden, Alfonso Zambon, Dan Niculescu-Duvaz, Caroline Springer, Roger S Lo and Richard Marais

J Invest Dermatol 133: 274-276; advance online publication, August 16, 2012; doi:10.1038/jid.2012.268

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