血管成形术中使用药物涂层球囊预后良好
关键信息
该研究纳入331例患者,并将其随机分配行紫杉醇涂层球囊经皮腔内血管成形术或仅行传统血管成形术,研究对这些患者进行了12个月的随访。结果发现,药物涂层球囊组与传统血管成形术组相比,前者血管通畅水平显著较高,而对靶病变血运重建术的需求仅为后者的1/8。
使用药物涂层球囊与标准血管成形术相比,可显著改善血管通畅水平并减少血管重建需求。
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In this trial with 12-month follow-up, researchers randomized 331 patients with superficial femoral and/or popliteal artery disease to undergo paclitaxel-coated balloon with percutaneous transluminal angioplasty (PTA) or conventional PTA. The group treated with the drug-coated balloon had significantly better patency and were nearly eight times less likely to require target lesion revascularization (P < .001).
Drug-coated balloon use is associated with significantly improved patency and reduction in need for revascularization when compared with standard angioplasty.
Circulation
Drug-Coated Balloon Versus Standard Percutaneous Transluminal Angioplasty for the Treatment of Superficial Femoral and/or Popliteal Peripheral Artery Disease: 12-Month Results From the IN.PACT SFA Randomized Trial
Circulation 2014 Dec 03;[EPub Ahead of Print], G Tepe, J Laird, P Schneider, M Brodmann, P Krishnan, A Micari, C Metzger, D Scheinert, T Zeller, DJ Cohen, DB Snead, B Alexander, M Landini, MR Jaff
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来源: PracticeUpdate
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