腮腺嗜酸细胞癌

Department of Oral and Maxillofacial Surgery, Peking University School, Hospital of Stomatology, Beijing 100081, China

Objectives/Hypothesis: The incidence of oncocytic carcinoma of the parotid gland is low, so a systematic evaluation of treatment strategies is lacking. We aimed to describe our experiences in treating this malignancy. Study Design: Retrospective study. Methods: We reviewed the files for 18 patients (14 males) of oncocytic carcinoma of the parotid gland in our institution from 1991 to 2011. Four patients underwent surgery alone, four surgery and postoperative radiotherapy, nine surgery and postoperative brachytherapy, and one radiotherapy alone. Median follow-up was 36 months (range 2-108 months). Results: The 5-year local control rate was 66.9%, overall survival 68.6%, disease progression-free survival 46.2%, and 5-year freedom from distant metastasis 61.0%. Clinical N category, local recurrence, and distant metastasis significantly influenced overall survival. Conclusions: Conservative parotidectomy is not radical enough to treat oncocytic carcinoma of the parotid gland. Elective neck dissection is recommended for patients with cancer stage T2 to 4. Surgery with postoperative 125I brachytherapy leads to good local control for patients with advanced disease or with positive or close resection margins. Copyright © 2012 The American Laryngological, Rhinological, and Otological Society, Inc.
 

Zhang, J.-G.; Department of Oral and Maxillofacial Surgery, Peking University School, Hospital of Stomatology, Beijing 100081, China; email:rszhang@126.com