采用远端尿道成形术治疗孤立性尿道舟状凹和尿道狭窄

Objective:

• Urethral strictures located in the fossa navicularis are common and are often managed with meatotomy or meatoplasty.

• Few data have described the outcomes for men after urethroplasty or patient satisfaction following these procedures.

Methods:

• In all, 93 men at two different institutions underwent surgical repair of distal urethral stricture disease using meatotomy (73) or meatoplasty (20), with 13/20 (65%) of the latter group undergoing substitution urethroplasty.

• In patients with lichen sclerosus (LS), all involved tissue was excised prior to reconstruction.

• In a subset of men undergoing meatotomy, patient satisfaction was evaluated by questionnaire.

Results:

• Average clinical follow-up for men undergoing distal urethroplasty was 61months.

• Successful reconstruction requiring no further intervention occurred in 84% of men overall. Subgroup analysis revealed success in 87% of men with meatotomy, 75% with meatoplasty and 66% with substitution urethroplasty.

• Men with LS had a significantly greater rate of stricture recurrence (20.5% vs 7.5%, P=0.04).

• Of the subset of men who completed a patient-based questionnaire 84% reported they were either satisfied or very satisfied with the results of their meatotomy.

Conclusions:

• We report the success of distal urethral stricture management.

• Meatal strictures may be approached successfully in a stepwise manner progressing from meatotomy to meatoplasty for longer recurrent strictures, with a high overall success rate for meatotomy.

• Although substitution grafts may be useful for men with longer distal strictures and those with LS, the risk of recurrence was significantly higher in this cohort.