潜藏外显子19 EGFR删除和EML4-ALK融合基因的肺腺癌1例

Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji Univ. School of Medicine Tongji Univ. Medical School Cancer Inst. Tongji Univ., No. 507 Zhengmin Road, Shanghai 200433, China

We report a man with advanced adenocarcinoma who harboring exon 19 (E746-A750del) epidermal growth factor receptor (EGFR) deletion and echinoderm microtubule-associated protein like 4-anaplastic lymphoma kinase (EML4-ALK) gene translocation in the re-biospy specimen. The patient was treated with erlotinib with a stable disease but progressed slowly, while crizotinib showed a complete response. © 2013 Elsevier Ireland Ltd.

Zhou, C.; Department of Medical Oncology, Shanghai Pulmonary Hospital, Tongji Univ. School of Medicine Tongji Univ. Medical School Cancer Inst. Tongji Univ., No. 507 Zhengmin Road, Shanghai 200433, China;