爱思唯尔期刊精选全文

		Free Radical Biology and Medicine
		中文标题: 高铁细胞色素C对过氧化氢诱导的线粒体细胞色素C氧化酶氧化损伤有保护作用
		英文标题: Ferricytochrome c protects mitochondrial cytochrome c oxidase against hydrogen peroxide-induced oxidative damage
		作者: Erik Sedlák, Marian Fabian, Neal C. Robinson and ...
		全文: An excess of ferricytochrome c protects purified mitochondrial cytochrome c oxidase and bound cardiolipin from hydrogen peroxide-induced oxidative modification. All of the peroxide-induced c...

		American Heart Journal
		中文标题: 血清镁与高血压和心血管疾病发病风险间缺乏关联
		英文标题: Lack of association between serum magnesium and the risks of hypertension and cardiovascular disease
		作者: Abigail May Khan MD, Lisa Sullivan PhD, Elizabeth ...
		全文: Background Experimental studies have linked hypomagnesemia with the development of vascular dysfunction, hypertension, and atherosclerosis. Prior clinical studies have yielded conflicting resul...

		Heart and Lung
		中文标题: 糖尿病对70岁以上患者行冠状动脉旁路移植术的影响
		英文标题: Impact of diabetes mellitus on patients over 70 years of age undergoing coronary artery bypass grafting
		作者: Qiang Ji MD, PhD, Yunqing Mei MD, PhD, Xisheng Wa...
		全文: Objective We evaluated in-hospital outcomes of diabetic and nondiabetic patients aged over 70 years after isolated coronary artery bypass grafting (CABG). Patients and Setting All patients aged...

		Seminars in Cancer Biology
		中文标题: 抑制SDF-1/CXCR4轴可以根除急性白血病？
		英文标题: Can inhibition of the SDF-1/CXCR4 axis eradicate acute leukemia?
		作者: Sigal Tavor and Isabelle Petit
		全文: Poor prognosis of acute leukemia with current treatments is mainly due to the relapse of the disease following chemotherapy. In the last decade, an emerging concept has proposed that the leuke...

		Seminars in Cancer Biology
		中文标题: 体细胞基因治疗的遗传风险
		英文标题: The genomic risk of somatic gene therapy
		作者: Olga Kustikova, Martijn Brugman and Christopher Ba...
		全文: Gene vectors with an untargeted insertion profile have been explored in preclinical models and clinical trials for the transfer of potentially therapeutic genetic information into somatic cells th...

		Seminars in Perinatology
		中文标题: 对专业学会关于剖宫产后阴道分娩指南的评价
		英文标题: A severity scoring system for risk assessment of patients with cardiogenic shock: A report from the SHOCK Trial and Registry Original Research Articl...
		作者: Emmanuel Bujold MD, MSc, FRCSC
		全文: The objective was to compare national guidelines regarding vaginal birth after cesarean. Along with the American College of Obstetricians and Gynecologists practice bulletin, guidelines from the Royal...

		Contraception
		中文标题: 肥胖妇女甾体避孕药的代谢和药代动力学：综述
		英文标题: Metabolism and pharmacokinetics of contraceptive steroids in obese women: a review
		作者: Alison B. Edelman, Ganesh Cherala and Frank Z. Sta...
		全文: The effect of obesity on drug metabolism and pharmacokinetics is poorly understood, and this is particularly true in regard to contraceptive steroids. This article will review the known and theo...

		Contraception
		中文标题: 避孕用黄体酮阴道环在哺乳期的应用
		英文标题: Progesterone vaginal ring for contraceptive use during lactation
		作者: Anita Nath and Regine Sitruk-Ware
		全文: The progesterone vaginal ring (PVR) has been shown to be effective as a contraceptive in breastfeeding women who need a better method of spacing pregnancies, and previous clinical trials of 1-ye...

		Gynecologic Oncology
		中文标题: 子宫内膜癌患者术前纤维蛋白原的预后意义
		英文标题: Prognostic significance of preoperative plasma fibrinogen in endometrial cancer
		作者: Fabio Ghezzi, Antonella Cromi, Gabriele Siesto, Si...
		全文: Objective To investigate the prognostic significance of preoperative plasma fibrinogen concentration, with particular focus on tumor dissemination and nodal involvement, in a substantial...

		Gynecologic Oncology
		中文标题: 卵巢癌的靶向试验
		英文标题: Targeted trials in ovarian cancer
		作者: Jonathan A. Ledermann , and Fharat A. Raja
		全文: The last five years has seen a major expansion in the number of clinical trials with molecular targeted agents in ovarian cancer. Most of the studies are with anti-angiogenic agents. This review...

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病例分析 [栏目介绍]

甲状腺功能亢进合并黄疸

王燕燕王曙

上海交通大学附属瑞金医院内分泌科

患者，女，69岁。2009年1月无明显诱因下出现乏力，当时程度较轻，未予以重视。2009年3月患者乏力症状加重，尿色逐渐加深，大便习惯改变，颜色变淡。4月18日入我院感染科治疗，诉轻度头晕、心慌，体重减轻10kg。无肝区疼痛，无发热，无腹痛、腹泻、腹胀、里急后重，无恶性、呕吐等。入院半月前于外院就诊，查肝功能：ALT 601IU/L，AST 785IU/L，TBIL 97.7umol/L，白蛋白 41g/L，甲状腺功能：游离T3 30.6pmol/L，游离T4 51.9pmol/L，心电图示快速房颤。

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