爱思唯尔期刊精选全文

		Free Radical Biology and Medicine
		中文标题: 氧化生成的碱基对细胞DNA的损伤
		英文标题: Oxidatively generated base damage to cellular DNA
		作者: Jean Cadet, Thierry Douki and Jean-Luc Ravanat
		全文: Search for the formation of oxidatively base damage in cellular DNA has been a matter of debate for more than 40 years due to the lack of accurate methods for the measurement of the lesions....

		Journal of Cardiac Failure
		中文标题: 心衰表现循证评估与临床预后：系统回顾
		英文标题: Evidence-Based Heart Failure Performance Measures and Clinical Outcomes: A Systematic Review
		作者: Jared Lane K. Maeda MPH, PhD(C)
		全文: Background Evidence-based performance measures for heart failure are increasingly being used to stimulate quality improvement efforts. Methods and Results A literature search was performed usin...

		American Heart Journal
		中文标题: 培哚普利与钙离子拮抗剂预防冠心病患者心脏事件和降低病死率的临床协同作用：EUROPA研究事后分析
		英文标题: Clinical synergy of perindopril and calcium-channel blocker in the prevention of cardiac events and mortality in patients with coronary artery disease...
		作者: Michel E. Bertrand MD, FRCP, FESC, FACC, Roberto F...
		全文: Background The purposes of the study were to determine the effects of addition of perindopril to long-term continuous treatment with calcium-channel blocker (CCB) on cardiac outcomes in the stable...

		American Journal of Cardiology
		中文标题: 丹麦西部地区伴或不伴糖尿病患者行经皮冠状动脉介入治疗的长期预后
		英文标题: Long-Term Outcomes After Percutaneous Coronary Intervention in Patients With and Without Diabetes Mellitus in Western DenmarkLong-Term Outcomes After ...
		作者: Lisette Okkels Jensen MD, PhD, Michael Maeng MD, P...
		全文: Patients with diabetes mellitus have worse outcomes after percutaneous coronary intervention than patients without diabetes mellitus. We compared the risk of stent thrombosis, myocardial infarction,...

		American Journal of Cardiology
		中文标题: 为何β受体阻滞剂不能作为没有并发症高血压的第一选择？
		英文标题: Why β-Blockers Should Not Be Used as First Choice in Uncomplicated Hypertension
		作者: Alberto Ranieri De Caterina MD, and Antonio Maria...
		全文: In the past 4 decades, β blockers (BBs) have been widely used in the treatment of uncomplicated hypertension and are still recommended as first-line agents in national and international guidelines....

		Contraception
		中文标题: 孕期前3个月外科流产的疼痛控制：随机对照试验的系统回顾
		英文标题: Pain control in first-trimester surgical abortion: a systematic review of randomized controlled trials
		作者: Regina M. Renner, Jeffrey T. Jensen, Mark D. Nicho...
		全文: Background First-trimester abortions especially cervical dilation and suction aspiration are associated with pain despite various methods of pain control. Study Design Following the guideline...

		Translational Research
		中文标题: 新型人血干细胞：治疗1型糖尿病的双刃剑
		英文标题: New type of human blood stem cell: a double-edged sword for the treatment of type 1 diabetes
		作者: Yong Zhaoa, Brian Lina, Michael Dingeldein, Chengs...
		全文: Type 1 diabetes (T1D) is an autoimmune disease caused by an autoimmune destruction of pancreatic islet insulin-producing cells. Autoimmunity and shortage of insulin-producing cells are 2 key issues...

		Free Radical Biology and Medicine
		中文标题: 衰老过程中的氧化应激、线粒体生物能量学和心磷脂
		英文标题: Oxidative stress, mitochondrial bioenergetics, and cardiolipin in aging
		作者: Giuseppe Paradies, Giuseppe Petrosillo, Valeria Pa...
		全文: Aging is a natural, complex, and multifactorial biological process associated with impairment of bioenergetic function, increased oxidative stress, attenuated ability to respond to stresses, and i...

		American Journal of Cardiology
		中文标题: 射频导管消融对房颤病人左心房大小、容积和功能影响的荟萃分析
		英文标题: Meta-Analysis of the Effect of Radiofrequency Catheter Ablation on Left Atrial Size, Volumes and Function in Patients With Atrial Fibrillation
		作者: Vinodh Jeevanantham MDa, William Ntim MD, Sankar D...
		全文: The effects of radiofrequency catheter ablation (RFCA) on left atrial (LA) size, volumes, and function in patients with atrial fibrillation (AF) are not well understood. The aim of this study...

		American Journal of Medicine
		中文标题: 应用生物标记物挑选病情复杂的病人
		英文标题: The Utility of Biomarkers in Sorting Out the Complex Patient
		作者: Christopher Moriates MD and Alan Maisel MD
		全文: Today's patients present with a complexity of illness far more significant than ever before. Risk factors, in particular for cardiovascular, renal, and metabolic diseases, often interact wit...

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甲状腺功能亢进合并黄疸

王燕燕王曙

上海交通大学附属瑞金医院内分泌科

患者，女，69岁。2009年1月无明显诱因下出现乏力，当时程度较轻，未予以重视。2009年3月患者乏力症状加重，尿色逐渐加深，大便习惯改变，颜色变淡。4月18日入我院感染科治疗，诉轻度头晕、心慌，体重减轻10kg。无肝区疼痛，无发热，无腹痛、腹泻、腹胀、里急后重，无恶性、呕吐等。入院半月前于外院就诊，查肝功能：ALT 601IU/L，AST 785IU/L，TBIL 97.7umol/L，白蛋白 41g/L，甲状腺功能：游离T3 30.6pmol/L，游离T4 51.9pmol/L，心电图示快速房颤。

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