爱思唯尔期刊精选全文

		Heart and Lung
		中文标题: 慢性阻塞性肺病患者疼痛的定性研究
		英文标题: Qualitative study of pain of patients with chronic obstructive pulmonary disease
		作者: Vibeke Lohne RN, PhD, Hanne Camilla Drangsholt Hee...
		全文: Objective This study evaluated the pain experiences of patients with chronic obstructive pulmonary disease (COPD). Sample We studied 16 patients with severe COPD. Design A semistructured interv...

		Seminars in Cancer Biology
		中文标题: p53通路的调节
		英文标题: Modulating the p53 pathway
		作者: Anwesha Dey, David P. Lane and Chandra S. Verma
		全文: p53 is a transcription factor that protects cells against stress, by modulating genes that induce growth arrest, repair, apoptosis, senescence or altered metabolism. Activation of p53 can potentia...

		Contraception
		中文标题: 依托孕烯植入物对血脂、肝功能检验和血红蛋白的作用
		英文标题: Effect of etonogestrel implant on serum lipids, liver function tests and hemoglobin levels
		作者: Berna Dilbaz, Ozlem Ozdegirmenci, Eray Caliskan, S...
		全文: Background This study aimed to assess the possible effects of etonogestrel implant (Implanon®, Organon, Oss, The Netherlands) on total cholesterol (TC), triglycerides (TG), high-density lipoprote...

		Seminars in Perinatology
		中文标题: 早产是成年高血压的危险因素吗？
		英文标题: Preterm Birth—An Emerging Risk Factor for Adult Hypertension?
		作者: Mikael Norman
		全文: Hypertension is a major risk factor for ischemic heart disease and stroke, which are leading causes of morbidity and death worldwide. Besides the contributions from genes and adult life-style, this...

		Gynecologic Oncology
		中文标题: 揭示黏液性卵巢癌的复杂性
		英文标题: Unmasking the complexities of mucinous ovarian carcinoma
		作者: Michael Frumovitz, Kathleen M. Schmeler, Anais Mal...
		全文: Objective Most collaborative studies for the treatment of primary and recurrent ovarian cancer have grouped all epithelial ovarian cancers together, leading to a common therapeutic approach to al...

		American Journal of Obstetrics and Gynecology
		中文标题: 子宫内孕酮、孕酮拮抗剂和受体调节剂：妇科应用综述
		英文标题: Intrauterine progestins, progesterone antagonists, and receptor modulators: a review of gynecologic applications
		作者: Maria Isabel Rodriguez MD, Meredith Warden MD, MPH...
		全文: Intrauterine progestins, progesterone receptor modulators, and antagonists have many important current and potential gynecologic applications. This article will describe the evidence for use of intr...

		Translational Research
		中文标题: 布洛芬诱导的超敏综合征
		英文标题: Ibuprofen-induced hypersensitivity syndrome
		作者: Radu M. Nanau and Manuela G. Neuman
		全文: Ibuprofen is a widely used antipyretic and analgesic nonsteroidal antiinflammatory drug (NSAID). With the aging of the population, there will be a significant increase in the prevalence of painf...

		Gastroenterology Clinics of North America
		中文标题: 内镜治疗胆道结石
		英文标题: Endoscopic Management of Biliary Ductal Stones
		作者: Kyo-Sang Yoo MD and Glen A. Lehman MD
		全文: Bile duct stone management has greatly changed in the past 2 decades. Open surgical techniques have mostly been replaced by transoral endoscopic techniques. Routine common bile duct stones can be ma...

		Free Radical Biology and Medicine
		中文标题: 1型糖尿病通过NOS, PARP, IκBα/NF-κB, MAPKs的激活和线粒体依赖途径导致大鼠...
		英文标题: Contribution of type 1 diabetes to rat liver dysfunction and cellular damage via activation of NOS, PARP, IκBα/NF-κB, MAPKs, and mitochondria-dependen...
		作者: Prasenjit Manna, Joydeep Das, Jyotirmoy Ghosh and ...
		全文: Diabetic mellitus, a chronic metabolic disorder, is one of the most important health problems in the world, especially in developing countries. Our earlier investigations reported the beneficial a...

		Free Radical Biology and Medicine
		中文标题: 铜、锌过氧化物歧化酶的过氧化机理
		英文标题: Mechanism of the peroxidase activity of Cu, Zn superoxide dismutase
		作者: Stefan I. Liochev and Irwin Fridovich
		全文: In addition to its very efficient catalysis of the dismutation of superoxide ( O2- ) into O2 plus H2O2, Cu, Zn SOD acts less efficiently as a non-specific peroxidase. This peroxidase activity is C...

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甲状腺功能亢进合并黄疸

王燕燕王曙

上海交通大学附属瑞金医院内分泌科

患者，女，69岁。2009年1月无明显诱因下出现乏力，当时程度较轻，未予以重视。2009年3月患者乏力症状加重，尿色逐渐加深，大便习惯改变，颜色变淡。4月18日入我院感染科治疗，诉轻度头晕、心慌，体重减轻10kg。无肝区疼痛，无发热，无腹痛、腹泻、腹胀、里急后重，无恶性、呕吐等。入院半月前于外院就诊，查肝功能：ALT 601IU/L，AST 785IU/L，TBIL 97.7umol/L，白蛋白 41g/L，甲状腺功能：游离T3 30.6pmol/L，游离T4 51.9pmol/L，心电图示快速房颤。

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