吸入性皮质激素与糖尿病发病及进展的风险

Inhaled Corticosteroids and the Risks of Diabetes Onset and Progression
作者:Samy Suissa,Abbas Kezouh,Pierre Ernst 【全球专家评论】
期刊: AM J MED2010年5月11期123卷

Abstract 

Background

Systemic corticosteroids are known to increase diabetes risk, but the effects of high-dose inhaled corticosteroids are unknown. We assessed whether the use and dose of inhaled corticosteroids increase the risk of diabetes onset and progression.

Methods

We formed a new-user cohort of patients treated for respiratory disease during 1990-2005, identified using the Quebec health insurance databases and followed through 2007 or until diabetes onset. The subcohort treated with oral hypoglycemics was followed until diabetes progression. A nested case-control analysis was used to estimate the rate ratios of diabetes onset and progression associated with current inhaled corti


学科代码:内科学 内分泌学与糖尿病   关键词:吸入性皮质激素与糖尿病发病及进展的风险
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