逆转录腺苷调节剂adenosine对冠状动脉旁路移植术发病率和死亡率的影响:RED-CABG随机对照试验
Effect of Adenosine-Regulating Agent Acadesine on Morbidity and Mortality Associated With Coronary Artery Bypass Grafting: The RED-CABG Randomized Controlled Trial
ABSTRACT
ABSTRACT | METHODS | RESULTS | COMMENT | CONCLUSIONS | AUTHOR INFORMATION | REFERENCES
Context Ischemia/reperfusion injury remains an important cause of morbidity and mortality after coronary artery bypass graft (CABG) surgery. In a meta-analysis of randomized controlled trials, perioperative and postoperative infusion of acadesine, a first-in-class adenosine-regulating agent, was associated with a reduction in early cardiac death, myocardial infarction, and combined adverse cardiac outcomes in participants undergoing on-pump CABG surgery.
Objective To assess the efficacy and safety of acadesine administered in the perioperative period in reducing
学科代码:外科学 关键词:Adenosine-Regulating Agent Acadesine Coronary Artery Bypass Graftin
来源: Journal of the American Medical Association
来源: Journal of the American Medical Association
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