在急性冠脉综合征患者中评估脂联素和复发性心血管事件风险:来自普伐他汀或阿托伐他汀评估和感染试验-心肌梗死中的溶栓22(PROVE IT–TIMI 22)试验的观察结果
Adiponectin, an adipocytokine, is secreted by fatty cells and exerts a regulatory role in atherogenesis, modulating foam cell formation and cellular adhesion. In stable atherosclerosis, plasma adiponectin has been reported to be associated with both increased and decreased cardiovascular risk. Recent data have suggested a possible discordant adverse risk relationship in acute coronary syndrome (ACS). Therefore, we investigated the association between adiponectin and cardiovascular events in patients with ACS.
METHODS:We measured plasma adiponectin in 3,931 patients stabilized following ACS and assessed the relationship with 2-year outcome. Patients were followed for
来源: ScienceDirect
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