氧化应激、胰岛素信号转导和糖尿病

Oxidative stress, insulin signaling, and diabetes
作者:Justin L. Rains and Sushil K. Jain 【全球专家评论】
期刊: FREE RADICAL BIO MED2011年2月5期50卷

Article Outline

Introduction
Insulin and normal insulin signaling
Reactive oxygen species and redox state
Hyperglycemia, oxidative stress, and diabetes
The influence of oxidative stress on insulin signaling
Mitochondrial dysfunction and insulin signaling
Ketosis and oxidative stress and insulin signaling
Insulin sensitivity and nutrient availability
PTEN and insulin sensitivity
Sleep restriction and insulin sensitivity
Therapy
Conclusion
Acknowledgements
References

Introduction

Diabetes is a complex metabolic disorder characterized by defects in the body's ability to control glucose and insulin homeostasis. Diabetes has become an epidemic and

学科代码:内分泌学与糖尿病   关键词:氧化应激、胰岛素信号转导和糖尿病
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