寄生虫和过敏性疾病:谜团的另一部份
Parasites and allergic disease: Another piece of the puzzle
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Key words: Parasites, allergens, molecular mimicry
Immunity to parasitic infections principally involves innate and adaptive TH2 responses and is accompanied by the development of IgE antibodies to parasite antigens. Epidemiologic and experimental studies suggest that helminth infections can modulate allergic disease,1 but cross-reactivity between helminth antigens and allergens that induce human allergic disease has been described. Tropomyosin from filarial parasites can induce IgE antibodies that cross-react with house dust mite allergens,2 and similarly, IgE responses to tropomyosins from Ascaris species cross-react with cockroach allergens.3
In the curren
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学科代码:内科学 关键词:Parasites allergens molecular mimicry
来源: J ALLERGY CLIN IMMUN
来源: J ALLERGY CLIN IMMUN
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