用药安全

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Arena和Vivus采取各自不同的方式回应CRL
Arena and Vivus Take Divergent Paths To CRL Response

2010-11-04

121

面对心血管问题REMS也无法挽救雅培开发的减肥药Meridi...
REMS Cannot Save Abbott's Obesity Drug Meridia In Face Of Ca...

2010-10-11

166

SFDA发布文迪雅使用警告，但尚未决定是暂停使用还是限制使用
China's Drug Regulators Issue Warning On Use Of Avandia Whil...

2010-09-30

300

生长素受体激动剂可减轻糖尿病胃轻瘫患者呕吐程度
Ghrelin Agonist Decreased Severe Vomiting in Patients with D...

2010-09-27

FDA允许治疗糖尿病药物文迪雅继续上市
FDA allows diabetes drug Avandia to remain on the market

2010-09-26

179

FDA调查糖尿病药物Actos膀胱癌风险
FDA investigating risk of bladder cancer in patients taking ...

2010-09-25

156

阿尔茨海默病患者初步研究显示噻唑烷二酮类药物安全性良好
Thiazolidinedione Safety Profile Good in Pilot Alzhmeier’s S...

2010-09-13

Solo Slim膳食补充剂被召回
Solo Slim 'dietary supplements' recalled after FDA finds the...

2010-08-11

230

出于对广泛使用的担心，减肥药注册报批的道路艰难
Obesity Drugs Face Tough Road To Approval Amid Fears Of Wide...

2010-08-11

159

FDA警告，避免孩子和宠物接触喷洒透皮潮热治疗药的上臂
Keep kids and pets away from arms sprayed with transdermal h...

2010-08-02

241

咨询委员会表示，只要增加新的警示信息和REMS，文迪雅便可免...
Avandia Can Be Saved With New Warnings and REMS, Advisory Cm...

2010-07-16

246

FDA广泛征求文迪雅意见
FDA Casts Wide Net For Advice on Avandia

2010-07-15

348

文迪雅评审委员会：FDA向咨询专家小组提出了5项选择
Avandia Committee Review FDA Puts Five Options On Table For ...

2010-07-13

243

勘误：FDA警告公众减肥药Alli有仿冒品

2010-03-03

253

FDA审查有关糖尿病药物文迪雅心血管风险的最新资料，但未提出...
FDA reviews new data on cardiovascular risks of diabetes dru...

2010-02-25

603

FDA警告，心血管疾病患者应禁用减肥药Meridia
Weight-loss drug Meridia not to be used in patients with CVD...

2010-01-25

553

FDA警告公众减肥药Alli有仿冒品
FDA warns public about counterfeit version of weight-loss dr...

2010-01-21

902

FDA警告Genzyme公司的部分注射剂产品可能受污染
FDA warns of possible contaminants in some injectable Genzym...

2009-11-18

776

“膳食补充剂”减肥产品排油果被令撤市
'Dietary supplement' weight-loss product Pai You Guo pulled ...

2009-11-18

574

糖尿病药物Byetta最新标签强调肾脏疾病风险
Risk for kidney problems highlighted in updated label for di...

2009-11-05

539

[栏目介绍]

标题

时间

阅读
数量

评论
数量

美国FDA警告糖尿病治疗药物Januvia或Janumet可...
Watch for pancreatitis in patients taking diabetes drugs Jan...

2009-10-10

1177

FDA警告公众减肥药Alli有仿冒品
FDA warns public about counterfeit version of weight-loss dr...

2010-01-21

902

FDA发布应用长效胰岛素Lantus与潜在癌症发生风险的警示
FDA early communication issued about use of long-acting insu...

2009-07-07

777

FDA警告Genzyme公司的部分注射剂产品可能受污染
FDA warns of possible contaminants in some injectable Genzym...

2009-11-18

776

FDA审查有关糖尿病药物文迪雅心血管风险的最新资料，但未提出...
FDA reviews new data on cardiovascular risks of diabetes dru...

2010-02-25

603

“膳食补充剂”减肥产品排油果被令撤市
'Dietary supplement' weight-loss product Pai You Guo pulled ...

2009-11-18

574

FDA警告，心血管疾病患者应禁用减肥药Meridia
Weight-loss drug Meridia not to be used in patients with CVD...

2010-01-25

553

糖尿病药物Byetta最新标签强调肾脏疾病风险
Risk for kidney problems highlighted in updated label for di...

2009-11-05

539

关于甲状腺功能亢进治疗药物丙基硫氧嘧啶肝毒性的警告
Warning about hepatotoxicity issued for hyperthyroidism drug...

2009-06-12

353

FDA广泛征求文迪雅意见
FDA Casts Wide Net For Advice on Avandia

2010-07-15

348

SFDA发布文迪雅使用警告，但尚未决定是暂停使用还是限制使用
China's Drug Regulators Issue Warning On Use Of Avandia Whil...

2010-09-30

300

勘误：FDA警告公众减肥药Alli有仿冒品

2010-03-03

253

咨询委员会表示，只要增加新的警示信息和REMS，文迪雅便可免...
Avandia Can Be Saved With New Warnings and REMS, Advisory Cm...

2010-07-16

246

文迪雅评审委员会：FDA向咨询专家小组提出了5项选择
Avandia Committee Review FDA Puts Five Options On Table For ...

2010-07-13

243

FDA警告，避免孩子和宠物接触喷洒透皮潮热治疗药的上臂
Keep kids and pets away from arms sprayed with transdermal h...

2010-08-02

241

Solo Slim膳食补充剂被召回
Solo Slim 'dietary supplements' recalled after FDA finds the...

2010-08-11

230

FDA允许治疗糖尿病药物文迪雅继续上市
FDA allows diabetes drug Avandia to remain on the market

2010-09-26

179

面对心血管问题REMS也无法挽救雅培开发的减肥药Meridi...
REMS Cannot Save Abbott's Obesity Drug Meridia In Face Of Ca...

2010-10-11

166

出于对广泛使用的担心，减肥药注册报批的道路艰难
Obesity Drugs Face Tough Road To Approval Amid Fears Of Wide...

2010-08-11

159

FDA调查糖尿病药物Actos膀胱癌风险
FDA investigating risk of bladder cancer in patients taking ...

2010-09-25

156

[栏目介绍]

标题

时间

阅读
数量

评论
数量

关于甲状腺功能亢进治疗药物丙基硫氧嘧啶肝毒性的警告
Warning about hepatotoxicity issued for hyperthyroidism drug...

2009-06-12

353

FDA发布应用长效胰岛素Lantus与潜在癌症发生风险的警示
FDA early communication issued about use of long-acting insu...

2009-07-07

777

美国FDA警告糖尿病治疗药物Januvia或Janumet可...
Watch for pancreatitis in patients taking diabetes drugs Jan...

2009-10-10

1177

糖尿病药物Byetta最新标签强调肾脏疾病风险
Risk for kidney problems highlighted in updated label for di...

2009-11-05

539

FDA警告Genzyme公司的部分注射剂产品可能受污染
FDA warns of possible contaminants in some injectable Genzym...

2009-11-18

776

“膳食补充剂”减肥产品排油果被令撤市
'Dietary supplement' weight-loss product Pai You Guo pulled ...

2009-11-18

574

FDA警告公众减肥药Alli有仿冒品
FDA warns public about counterfeit version of weight-loss dr...

2010-01-21

902

FDA警告，心血管疾病患者应禁用减肥药Meridia
Weight-loss drug Meridia not to be used in patients with CVD...

2010-01-25

553

FDA审查有关糖尿病药物文迪雅心血管风险的最新资料，但未提出...
FDA reviews new data on cardiovascular risks of diabetes dru...

2010-02-25

603

勘误：FDA警告公众减肥药Alli有仿冒品

2010-03-03

253

文迪雅评审委员会：FDA向咨询专家小组提出了5项选择
Avandia Committee Review FDA Puts Five Options On Table For ...

2010-07-13

243

FDA广泛征求文迪雅意见
FDA Casts Wide Net For Advice on Avandia

2010-07-15

348

咨询委员会表示，只要增加新的警示信息和REMS，文迪雅便可免...
Avandia Can Be Saved With New Warnings and REMS, Advisory Cm...

2010-07-16

246

FDA警告，避免孩子和宠物接触喷洒透皮潮热治疗药的上臂
Keep kids and pets away from arms sprayed with transdermal h...

2010-08-02

241

Solo Slim膳食补充剂被召回
Solo Slim 'dietary supplements' recalled after FDA finds the...

2010-08-11

230

出于对广泛使用的担心，减肥药注册报批的道路艰难
Obesity Drugs Face Tough Road To Approval Amid Fears Of Wide...

2010-08-11

159

FDA调查糖尿病药物Actos膀胱癌风险
FDA investigating risk of bladder cancer in patients taking ...

2010-09-25

156

FDA允许治疗糖尿病药物文迪雅继续上市
FDA allows diabetes drug Avandia to remain on the market

2010-09-26

179

阿尔茨海默病患者初步研究显示噻唑烷二酮类药物安全性良好
Thiazolidinedione Safety Profile Good in Pilot Alzhmeier’s S...

2010-09-13

SFDA发布文迪雅使用警告，但尚未决定是暂停使用还是限制使用
China's Drug Regulators Issue Warning On Use Of Avandia Whil...

2010-09-30

300

内分泌学与糖尿病

病例分析

甲状腺功能亢进合并黄疸

王燕燕王曙

上海交通大学附属瑞金医院内分泌科

患者，女，69岁。2009年1月无明显诱因下出现乏力，当时程度较轻，未予以重视。2009年3月患者乏力症状加重，尿色逐渐加深，大便习惯改变，颜色变淡。4月18日入我院感染科治疗，诉轻度头晕、心慌，体重减轻10kg。无肝区疼痛，无发热，无腹痛、腹泻、腹胀、里急后重，无恶性、呕吐等。入院半月前于外院就诊，查肝功能：ALT 601IU/L，AST 785IU/L，TBIL 97.7umol/L，白蛋白 41g/L，甲状腺功能：游离T3 30.6pmol/L，游离T4 51.9pmol/L，心电图示快速房颤。

医学数据库