中枢神经系统中病理和生理性自身抗体
Pathogenic and physiological autoantibodies in the central nervous system
Abstract
Summary: In this article, we review the current knowledge on pathological and physiological autoantibodies directed toward structures in the central nervous system (CNS) with an emphasis on their regulation and origin. Pathological autoantibodies in the CNS that are associated with autoimmunity often lead to severe neurological deficits via inflammatory processes such as encephalitis. In some instances, however, autoantibodies function as a marker for diagnostic purposes without contributing to the pathological process and/or disease progression. The existence of naturally occurring physiological autoantibodies has been known for a long time, and their role in maintaining homeostasi
学科代码:基础医学 关键词:naturally occurring autoantibo central nervous system B-lymphocyte;autoimmunity paraneoplastic antibodies
来源: Immunological Reviews
来源: Immunological Reviews
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