用药安全

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公众批评向中国政府施压，调低药价势在必行
Public Criticism Puts Pressure On Chinese Government To Redu...

2010-07-01

227

辉瑞在Mylotarg获得FDA快速批准后10年因安全问题而...
Pfizer Pulls Mylotarg For Safety 10 Years After Accelerated ...

2010-06-30

306

FDA将不予警告直接执行NDI申报要求
FDA Will Enforce NDI Notification Requirement Without Warnin...

2010-06-25

258

FDA声明魔力咖啡“膳食补充剂”中含有万艾可样化学成分
FDA states Magic Power Coffee 'dietary supplement' contains ...

2010-06-24

218

国际制药协会签署试验数据发表原则，无论试验结果如何均应公布
International Pharma Associations Lay Principles For Publish...

2010-06-24

165

安全性和有效性顾虑促使白血病治疗药Mylotarg(吉妥单抗...
Safety and efficacy concerns prompt voluntary recall of leuk...

2010-06-24

352

FDA警告：假冒达菲含有青霉素样物质
Fake Tamiflu contains penicillin-like substance, FDA warns

2010-06-23

194

建议在使用医用滴管对婴儿点滴维生素D补充剂时谨慎行事
Care advised when using medicine droppers to dispense vitami...

2010-06-18

223

中国放手尝试更为开放的膳食补充品法规
China Takes "Baby Steps" Toward More Open Supplement Regulat...

2010-06-18

218

麦克尼尔公司扩大早先有霉味药品的召回范围，将某些泰诺和苯海拉...
McNeil expands earlier musty-odor recall to include some Tyl...

2010-06-18

250

如果诺华的Gilenia扫除了安全性障碍，那么其他MS口服药...
If Novartis's Gilenia Clears Safety Hurdle,Other Oral MS Dru...

2010-06-11

245

欧洲研究提供了更多丙戊酸致畸性的数据
European Study Provides More Data on Teratogenicity of Valpr...

2010-06-11

244

PediaCare预防性召回部分产品
Precautionary recall of certain PediaCare products initiated

2010-06-10

217

HIV治疗药物Selzentry更改标签，强调肾功能损害患者...
Label changes for HIV drug Selzentry highlight safe use in p...

2010-06-10

176

因出现过敏反应，百特公司将2个批号的免疫球蛋白撤市
Allergic reactions prompt market withdrawal of 2 lots of Bax...

2010-06-09

152

FDA从强生召回事件中吸取教训，拟加强OTC监管并寻求新的权...
FDA To Toughen OTC Oversight, Seek New Authority In Wake Of ...

2010-06-02

475

Baxter在药瓶内发现玻璃微粒，主动召回Hylenex
Glass particles found in vials of Hylenex trigger recall

2010-05-31

221

FDA称，服用质子泵抑制剂可能会增加骨折风险
Possible increased risk of fractures with use of PPIs, says ...

2010-05-28

274

由减肥药赛尼可和阿莱所致的少数几例重度肝损伤促使FDA命令其...
Rare cases of severe liver injury with weight-loss drugs Xen...

2010-05-28

276

止痛药Ultram(曲马多)的新版说明书对自杀和过量用药进行...
Warnings about suicide and overdose highlighted on updated l...

2010-05-27

302

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含甲氧氯普胺药物应添加黑框警告，并实施“风险评估和最小化计划...
Boxed warning, risk mitigation strategy required for metoclo...

2009-03-02

493

诺华疫苗召回数个批次的Fluvirin Luer-Lok预充...
Novartis Vaccines recalls several lots of Fluvirin Luer-Lok ...

2009-02-25

487

单个批次的生物碱-塞尔策产品因药品标签错误而被召回
Single lot of Alka-Seltzer product recalled for labeling err...

2009-12-11

478

FDA出台新措施以促进哮喘治疗中安全使用长效β受体激动剂
FDA announces new measures to promote safe use of long-actin...

2010-02-21

477

警惕静脉铁剂Dexferrum致过敏反应
Watch for anaphylaxis in patients receiving parenteral iron ...

2009-10-22

476

抗抑郁药地昔帕明更新药物标签，补充新的安全性信息
Label for antidepressant Norpramin updated with new safety i...

2009-12-04

475

FDA从强生召回事件中吸取教训，拟加强OTC监管并寻求新的权...
FDA To Toughen OTC Oversight, Seek New Authority In Wake Of ...

2010-06-02

475

FDA发布警告称HIV治疗药物Videx可导致非肝硬化性门静...
FDA issues warning about use of HIV drug Videx and noncirrho...

2010-02-02

473

麦克尼尔公司扩大部分市售的泰诺关节炎止痛产品的召回范围
McNeil expands recall of certain Tylenol products marketed f...

2009-12-31

473

多发性硬化症治疗药Tysabri的说明书针对进行性多灶性白质...
Label for MS drug Tysabri updated regarding risk for progres...

2010-02-09

472

抗HIV药物Lexiva更新标签，详述心血管风险
Cardiovascular risks detailed in updated label for HIV drug ...

2009-12-07

466

由于担心污染，FDA和Hospira召回部分批次的丙泊酚乳剂...
Contamination concern prompts recall of some lots of Hospira...

2009-11-12

464

儿童不慎二次接触睾丸酮涂剂的报告促使FDA采取行动
Reports of inadvertent secondary exposure to testosterone ge...

2009-05-08

462

Caraco牌地高辛因片剂大小不一而被召回
Tablet size variability leads to recall of Caraco brand digo...

2009-06-12

461

公司自愿召回一些NSAID酮咯酸瓶装注射剂
Company voluntary recalls some vials of injectable NSAID Ket...

2009-10-23

459

早孕反应药Nzu中含有大量的毒素
Morning sickness remedy known as Nzu found to contain high l...

2010-01-06

455

FDA建议对免疫性血小板减少性紫癜患者慎用免疫球蛋白制剂Wi...
FDA advises caution with use of immunoglobulin WinRho SDF in...

2010-03-12

450

由于担心盐酸普罗帕酮片活性成分超标，华生公司自愿在全国范围内...
Nationwide voluntary recall of propafenone HCL tablets due t...

2009-03-30

448

FDA称唑尼沙胺治疗可导致某些患者发生代谢性酸中毒
FDA says treatment with zonisamide can cause metabolic acido...

2009-02-27

447

正在做进一步调查，以确定服用二磷酸盐口服药是否与某些股骨骨折...
Further investigation underway to determine whether use of o...

2010-03-15

444

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“膳食补充剂”减肥产品排油果被令撤市
'Dietary supplement' weight-loss product Pai You Guo pulled ...

2009-11-18

574

又在一种针对勃起功能障碍的“膳食补充剂”中检出含有未申报的万...
Analysis of another 'dietary supplement' for ED reveals unde...

2009-11-20

549

FDA对Plavix与Prilosec联合用药提出警告
FDA cautions against concomitant use of Plavix and Prilosec

2009-11-20

1403

FDA发现某些膳食补充剂中含有类固醇而敦促其召回
FDA finding of steroids in certain dietary supplements trigg...

2009-11-20

439

宝洁召回一些批次的Vicks Sinex鼻喷雾剂
Proctor & Gamble recalls some lots of Vicks nasal spray

2009-11-24

837

抗抑郁药地昔帕明更新药物标签，补充新的安全性信息
Label for antidepressant Norpramin updated with new safety i...

2009-12-04

475

抗HIV药物Lexiva更新标签，详述心血管风险
Cardiovascular risks detailed in updated label for HIV drug ...

2009-12-07

466

FDA提醒医务人员，孕妇服用丙戊酸盐可使胎儿出生缺陷的风险增...
FDA reminds practitioners of risk of birth defects when preg...

2009-12-08

686

单个批次的生物碱-塞尔策产品因药品标签错误而被召回
Single lot of Alka-Seltzer product recalled for labeling err...

2009-12-11

478

双氯芬酸产品标签更新，警示该品可导致肝脏酶升高
Updated labels for diclofenac products now contain warnings ...

2009-12-11

559

赛诺菲巴斯德主动召回4批效力降低的儿童H1N1疫苗
Four lots of pediatric H1N1 vaccine voluntarily recalled for...

2009-12-18

637

抗高血压药Cleviprex的多个药瓶中检出微粒物质后有11...
Eleven lots of antihypertensive Cleviprex recalled after det...

2009-12-21

711

麦克尼尔公司扩大部分市售的泰诺关节炎止痛产品的召回范围
McNeil expands recall of certain Tylenol products marketed f...

2009-12-31

473

早孕反应药Nzu中含有大量的毒素
Morning sickness remedy known as Nzu found to contain high l...

2010-01-06

455

FDA警告公众减肥药Alli有仿冒品
FDA warns public about counterfeit version of weight-loss dr...

2010-01-21

902

机遇来临：诺华与GenVec签署关于听力损伤药物研发的协议
The Sound Of Opportunity: Novartis Inks Deal With GenVec For...

2010-01-21

548

FDA警告，心血管疾病患者应禁用减肥药Meridia
Weight-loss drug Meridia not to be used in patients with CVD...

2010-01-25

553

骨髓瘤药物万珂修改针对肝损害患者的用药说明
Dosing instructions for myeloma drug Velcade modified for pa...

2010-01-28

419

FDA发布警告称HIV治疗药物Videx可导致非肝硬化性门静...
FDA issues warning about use of HIV drug Videx and noncirrho...

2010-02-02

473

抗精神病药再普乐(Zyprexa)产品标签添加青少年用药注意...
Cautionary notes about use in adolescents added to label for...

2010-02-03

552

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病例分析

甲状腺功能亢进合并黄疸

王燕燕王曙

上海交通大学附属瑞金医院内分泌科

患者，女，69岁。2009年1月无明显诱因下出现乏力，当时程度较轻，未予以重视。2009年3月患者乏力症状加重，尿色逐渐加深，大便习惯改变，颜色变淡。4月18日入我院感染科治疗，诉轻度头晕、心慌，体重减轻10kg。无肝区疼痛，无发热，无腹痛、腹泻、腹胀、里急后重，无恶性、呕吐等。入院半月前于外院就诊，查肝功能：ALT 601IU/L，AST 785IU/L，TBIL 97.7umol/L，白蛋白 41g/L，甲状腺功能：游离T3 30.6pmol/L，游离T4 51.9pmol/L，心电图示快速房颤。

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