用药安全

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抗抑郁药地昔帕明更新药物标签，补充新的安全性信息
Label for antidepressant Norpramin updated with new safety i...

2009-12-04

475

宝洁召回一些批次的Vicks Sinex鼻喷雾剂
Proctor & Gamble recalls some lots of Vicks nasal spray

2009-11-24

837

又在一种针对勃起功能障碍的“膳食补充剂”中检出含有未申报的万...
Analysis of another 'dietary supplement' for ED reveals unde...

2009-11-20

549

FDA对Plavix与Prilosec联合用药提出警告
FDA cautions against concomitant use of Plavix and Prilosec

2009-11-20

1403

FDA发现某些膳食补充剂中含有类固醇而敦促其召回
FDA finding of steroids in certain dietary supplements trigg...

2009-11-20

439

FDA警告：部分局麻药应避免关节腔内持续输注
Avoid continuous intraarticular infusions of certain local a...

2009-11-18

529

FDA警告Genzyme公司的部分注射剂产品可能受污染
FDA warns of possible contaminants in some injectable Genzym...

2009-11-18

776

“膳食补充剂”减肥产品排油果被令撤市
'Dietary supplement' weight-loss product Pai You Guo pulled ...

2009-11-18

574

由于担心污染，FDA和Hospira召回部分批次的丙泊酚乳剂...
Contamination concern prompts recall of some lots of Hospira...

2009-11-12

464

糖尿病药物Byetta最新标签强调肾脏疾病风险
Risk for kidney problems highlighted in updated label for di...

2009-11-05

539

服用肿瘤坏死因子阻断剂Rituxan的类风湿性关节炎患者中又...
Another case of PML occurs in patient with RA who took TNF-b...

2009-10-28

502

公司自愿召回一些NSAID酮咯酸瓶装注射剂
Company voluntary recalls some vials of injectable NSAID Ket...

2009-10-23

459

警惕静脉铁剂Dexferrum致过敏反应
Watch for anaphylaxis in patients receiving parenteral iron ...

2009-10-22

476

葛兰素史克公司和FDA警告不要雾化吸入依乐韦
GSK and FDA warn against unapproved nebulization of flu drug...

2009-10-15

686

肝素药典条款修订提高药物安全性但可能给用药带来影响
Changes to heparin improve drug safety but may impact dosing

2009-10-10

724

FDA发布关于铁鳌合剂Exjade安全性的早期沟通信息
FDA issues early communication about safety of iron chelator...

2009-10-10

715

美国FDA警告糖尿病治疗药物Januvia或Janumet可...
Watch for pancreatitis in patients taking diabetes drugs Jan...

2009-10-10

1177

确保达菲口服混悬液的用药指导与分药刻度计相一致
Make sure dosing instructions for oral suspension of Tamiflu...

2009-09-29

705

麦克尼尔公司预防性召回某些儿童用对乙酰氨基酚制品
McNeil conducts precautionary recall of certain children's T...

2009-09-29

553

异丙嗪的最新说明书中强调其静脉用药有严重组织损伤的风险
Updated label for promethazine highlights risk of severe tis...

2009-09-18

763

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FDA警告，避免孩子和宠物接触喷洒透皮潮热治疗药的上臂
Keep kids and pets away from arms sprayed with transdermal h...

2010-08-02

241

FDA研究者警示下腔静脉滤器的安全性问题
FDA_ Researchers Flag Safety Problems With Vena Cava Filters

2010-08-20

239

FDA提请公众注意银屑病药物Raptiva所致严重不良事件
FDA advises public of serious adverse event with psoriasis d...

2009-02-25

235

FDA警告消费者膳食补充剂Venom HYPERDRIVE ...
FDA warns consumers about dietary supplement containing unde...

2009-02-02

233

FDA称尽管轮状病毒疫苗中查出少许猪病毒的DNA ，但仍可以...
Although porcine virus DNA bits found in rotavirus vaccines,...

2010-05-19

233

Solo Slim膳食补充剂被召回
Solo Slim 'dietary supplements' recalled after FDA finds the...

2010-08-11

230

公众批评向中国政府施压，调低药价势在必行
Public Criticism Puts Pressure On Chinese Government To Redu...

2010-07-01

227

Mr Magic含有万艾可样化学成分被撤市
Mr Magic Male Enhancer pulled from market after FDA analysis...

2010-08-30

227

抗生素替格环素的说明书添加了死亡风险增加的警告
Label updates for antibiotic Tygacil warn of increased morta...

2010-09-04

226

Octapharma公司召回所有批次的免疫球蛋白制剂Octa...
All lots of immune globulin product Octagam recalled amid co...

2010-09-30

226

Octagam存在血栓栓塞风险被召回
Immune globulin product Octagam recalled amid concerns of in...

2010-08-31

223

建议在使用医用滴管对婴儿点滴维生素D补充剂时谨慎行事
Care advised when using medicine droppers to dispense vitami...

2010-06-18

223

Baxter在药瓶内发现玻璃微粒，主动召回Hylenex
Glass particles found in vials of Hylenex trigger recall

2010-05-31

221

FDA称 “蛇油”口服液——“神奇矿物质补充剂”按说明使用时...
FDA says oral 'snake oil' product Miracle Mineral Supplement...

2010-08-05

219

中国放手尝试更为开放的膳食补充品法规
China Takes "Baby Steps" Toward More Open Supplement Regulat...

2010-06-18

218

FDA声明魔力咖啡“膳食补充剂”中含有万艾可样化学成分
FDA states Magic Power Coffee 'dietary supplement' contains ...

2010-06-24

218

PediaCare预防性召回部分产品
Precautionary recall of certain PediaCare products initiated

2010-06-10

217

Bodee自愿在全国范围内召回Zencore Plus
Bodee issues voluntary nationwide recall of Zencore Plus

2009-03-23

217

阿瓦斯汀作为乳腺癌治疗药物的审议仔细权衡了其临床效益与相关统...
Avastin Breast Cancer Approval Debate Pits Clinical Benefit ...

2010-07-28

213

FDA对诺华/Orion公司生产的帕金森病药物Stalevo...
FDA Starts Its Second Safety Investigation Into Novartis/Ori...

2010-08-25

210

[栏目介绍]

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FDA声明魔力咖啡“膳食补充剂”中含有万艾可样化学成分
FDA states Magic Power Coffee 'dietary supplement' contains ...

2010-06-24

218

国际制药协会签署试验数据发表原则，无论试验结果如何均应公布
International Pharma Associations Lay Principles For Publish...

2010-06-24

165

安全性和有效性顾虑促使白血病治疗药Mylotarg(吉妥单抗...
Safety and efficacy concerns prompt voluntary recall of leuk...

2010-06-24

352

FDA将不予警告直接执行NDI申报要求
FDA Will Enforce NDI Notification Requirement Without Warnin...

2010-06-25

258

辉瑞在Mylotarg获得FDA快速批准后10年因安全问题而...
Pfizer Pulls Mylotarg For Safety 10 Years After Accelerated ...

2010-06-30

306

公众批评向中国政府施压，调低药价势在必行
Public Criticism Puts Pressure On Chinese Government To Redu...

2010-07-01

227

中国引起了欧盟企业的关注，但监管风险令人担忧
China Gaining Attention From EU Companies, But Regulatory Ri...

2010-07-05

162

文迪雅评审委员会：FDA向咨询专家小组提出了5项选择
Avandia Committee Review FDA Puts Five Options On Table For ...

2010-07-13

243

FDA广泛征求文迪雅意见
FDA Casts Wide Net For Advice on Avandia

2010-07-15

348

咨询委员会表示，只要增加新的警示信息和REMS，文迪雅便可免...
Avandia Can Be Saved With New Warnings and REMS, Advisory Cm...

2010-07-16

246

8个批次1 mg吸塑包装的Coumadin被召回
Company recalls 8 lots of Coumadin in 1-mg blister

2010-07-20

168

FDA开展对ARB 致癌风险和应用状况的审查工作
FDA reviewing cancer risk and use of ARBs

2010-07-20

640

阿瓦斯汀作为乳腺癌治疗药物的审议仔细权衡了其临床效益与相关统...
Avastin Breast Cancer Approval Debate Pits Clinical Benefit ...

2010-07-28

213

FDA警告，避免孩子和宠物接触喷洒透皮潮热治疗药的上臂
Keep kids and pets away from arms sprayed with transdermal h...

2010-08-02

241

FDA发布警告，使用抗生素Cubicin可能导致嗜酸粒细胞肺...
FDA issues warning about use of antibiotic Cubicin and devel...

2010-08-02

299

FDA的产品分析敦促厂家召回“膳食补充剂”Ejaculoid...
FDA product analysis prompts recall of 'dietary supplements'...

2010-08-05

129

FDA称 “蛇油”口服液——“神奇矿物质补充剂”按说明使用时...
FDA says oral 'snake oil' product Miracle Mineral Supplement...

2010-08-05

219

鉴于有微粒物质污染，两个批号的非甾体抗炎药静脉注射液NeoP...
Two lots of IV NSAID NeoProfen recalled amid concerns of par...

2010-08-05

140

静脉输注口服尼莫地平的报告迫使FDA增加安全警告
More reports of IV administration of oral nimodipine trigger...

2010-08-05

154

强生保守估计其OTC生产整改进程
J &J Keeps Expectations Conservative For OTC Manufacturing R...

2010-08-05

162

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病例分析

甲状腺功能亢进合并黄疸

王燕燕王曙

上海交通大学附属瑞金医院内分泌科

患者，女，69岁。2009年1月无明显诱因下出现乏力，当时程度较轻，未予以重视。2009年3月患者乏力症状加重，尿色逐渐加深，大便习惯改变，颜色变淡。4月18日入我院感染科治疗，诉轻度头晕、心慌，体重减轻10kg。无肝区疼痛，无发热，无腹痛、腹泻、腹胀、里急后重，无恶性、呕吐等。入院半月前于外院就诊，查肝功能：ALT 601IU/L，AST 785IU/L，TBIL 97.7umol/L，白蛋白 41g/L，甲状腺功能：游离T3 30.6pmol/L，游离T4 51.9pmol/L，心电图示快速房颤。

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