用药安全

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FDA研究者警示下腔静脉滤器的安全性问题
FDA_ Researchers Flag Safety Problems With Vena Cava Filters

2010-08-20

239

WHO宣布猪流感大流行结束，但仍有可能出现第二波疫情
WHO Declares An End To Swine Flu Pandemic_ But Says A Second...

2010-08-16

158

Novacare公司召回大量治疗勃起功能障碍的非处方药
Novacare recalls numerous OTC products for erectile dysfunct...

2010-08-14

175

ED膳食补充剂被召回
Erectile dysfunction 'dietary supplement' recalled after FDA...

2010-08-11

130

Solo Slim膳食补充剂被召回
Solo Slim 'dietary supplements' recalled after FDA finds the...

2010-08-11

230

出于对广泛使用的担心，减肥药注册报批的道路艰难
Obesity Drugs Face Tough Road To Approval Amid Fears Of Wide...

2010-08-11

159

FDA的产品分析敦促厂家召回“膳食补充剂”Ejaculoid...
FDA product analysis prompts recall of 'dietary supplements'...

2010-08-05

129

FDA称 “蛇油”口服液——“神奇矿物质补充剂”按说明使用时...
FDA says oral 'snake oil' product Miracle Mineral Supplement...

2010-08-05

219

鉴于有微粒物质污染，两个批号的非甾体抗炎药静脉注射液NeoP...
Two lots of IV NSAID NeoProfen recalled amid concerns of par...

2010-08-05

140

静脉输注口服尼莫地平的报告迫使FDA增加安全警告
More reports of IV administration of oral nimodipine trigger...

2010-08-05

154

强生保守估计其OTC生产整改进程
J &J Keeps Expectations Conservative For OTC Manufacturing R...

2010-08-05

162

FDA警告，避免孩子和宠物接触喷洒透皮潮热治疗药的上臂
Keep kids and pets away from arms sprayed with transdermal h...

2010-08-02

241

FDA发布警告，使用抗生素Cubicin可能导致嗜酸粒细胞肺...
FDA issues warning about use of antibiotic Cubicin and devel...

2010-08-02

299

阿瓦斯汀作为乳腺癌治疗药物的审议仔细权衡了其临床效益与相关统...
Avastin Breast Cancer Approval Debate Pits Clinical Benefit ...

2010-07-28

213

8个批次1 mg吸塑包装的Coumadin被召回
Company recalls 8 lots of Coumadin in 1-mg blister

2010-07-20

168

FDA开展对ARB 致癌风险和应用状况的审查工作
FDA reviewing cancer risk and use of ARBs

2010-07-20

640

咨询委员会表示，只要增加新的警示信息和REMS，文迪雅便可免...
Avandia Can Be Saved With New Warnings and REMS, Advisory Cm...

2010-07-16

246

FDA广泛征求文迪雅意见
FDA Casts Wide Net For Advice on Avandia

2010-07-15

348

文迪雅评审委员会：FDA向咨询专家小组提出了5项选择
Avandia Committee Review FDA Puts Five Options On Table For ...

2010-07-13

243

中国引起了欧盟企业的关注，但监管风险令人担忧
China Gaining Attention From EU Companies, But Regulatory Ri...

2010-07-05

162

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双氯芬酸产品标签更新，警示该品可导致肝脏酶升高
Updated labels for diclofenac products now contain warnings ...

2009-12-11

559

命名相近促使GERD药Kapidex更换商标，以减少发药错误
Name similarities prompt rebranding of GERD drug Kapidex to ...

2010-03-09

559

FDA警告，心血管疾病患者应禁用减肥药Meridia
Weight-loss drug Meridia not to be used in patients with CVD...

2010-01-25

553

麦克尼尔公司预防性召回某些儿童用对乙酰氨基酚制品
McNeil conducts precautionary recall of certain children's T...

2009-09-29

553

抗HIV药物Intelence更新标签信息，强调严重皮肤反应...
Updated label for HIV drug Intelence emphasizes risk of seve...

2009-09-07

552

抗精神病药再普乐(Zyprexa)产品标签添加青少年用药注意...
Cautionary notes about use in adolescents added to label for...

2010-02-03

552

又在一种针对勃起功能障碍的“膳食补充剂”中检出含有未申报的万...
Analysis of another 'dietary supplement' for ED reveals unde...

2009-11-20

549

机遇来临：诺华与GenVec签署关于听力损伤药物研发的协议
The Sound Of Opportunity: Novartis Inks Deal With GenVec For...

2010-01-21

548

美公司撤回Zicam感冒鼻腔药品，但对FDA警告其可致嗅觉失...
Company pulls Zicam intranasal products despite disagreement...

2009-06-29

543

暂停使用轮状病毒疫苗Rotarix，但允许使用RotaTeq
Use of rotavirus vaccine Rotarix temporarily suspended: Okay...

2010-03-25

540

糖尿病药物Byetta最新标签强调肾脏疾病风险
Risk for kidney problems highlighted in updated label for di...

2009-11-05

539

新的产品标签强调Chantix、Wellbutrin和Zyb...
Serious neuropsychiatric risks of Chantix, Wellbutrin, and Z...

2009-07-02

530

FDA警告：部分局麻药应避免关节腔内持续输注
Avoid continuous intraarticular infusions of certain local a...

2009-11-18

529

GAO: FDA对GRAS成分疏于监管可能滋生问题
FDA's Lack Of Oversight Into GRAS Ingredients Could Sprout P...

2010-03-11

527

FDA采用了新增的促进促红细胞生成素类药物安全使用的策略
FDA adopts additional strategies to promote safe use of eryt...

2010-02-20

520

FDA警告应用阿片类止痛药丙氧芬有过量致死的风险
FDA warns of fatal overdose risk with use of opioid propoxyp...

2009-07-10

520

美国发现更多的问题减肥产品
FDA uncovers additional tainted weight loss products

2009-03-25

504

因存在潜在健康危险，ION Labs公司召回在阿拉巴马州销售...
ION Labs Inc recalls Influend cough and cold products in Ala...

2009-04-16

504

服用肿瘤坏死因子阻断剂Rituxan的类风湿性关节炎患者中又...
Another case of PML occurs in patient with RA who took TNF-b...

2009-10-28

502

ETHEX在美国全国范围内向批发商自愿召回产前用处方补充剂和...
ETHEX issues voluntary nationwide recall of prescription pre...

2009-02-05

496

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FDA对抗生素头孢吡肟致死亡风险增加的审查减轻了早前的担忧
FDA review allays earlier concerns of increased mortality ri...

2009-06-29

304

美FDA修订HPV疫苗Gardasil的标签，加强接种后出现...
Label for HPV vaccine Gardasil revised to strengthen warning...

2009-06-30

604

美FDA对精神兴奋药物治疗患儿的猝死数据持谨慎态度
FDA takes cautionary stance on sudden death data from study ...

2009-06-30

434

FDA正调查减肥药奥利司他致肝损伤的报告
FDA looking into reports of liver injury with weight loss dr...

2009-08-31

813

抗HIV药物Intelence更新标签信息，强调严重皮肤反应...
Updated label for HIV drug Intelence emphasizes risk of seve...

2009-09-07

552

美国FDA：注意使用抗器官排斥药Myfortic的患者发生纯...
Watch for pure red cell aplasia in patients taking transplan...

2009-09-09

634

异丙嗪的最新说明书中强调其静脉用药有严重组织损伤的风险
Updated label for promethazine highlights risk of severe tis...

2009-09-18

763

确保达菲口服混悬液的用药指导与分药刻度计相一致
Make sure dosing instructions for oral suspension of Tamiflu...

2009-09-29

705

麦克尼尔公司预防性召回某些儿童用对乙酰氨基酚制品
McNeil conducts precautionary recall of certain children's T...

2009-09-29

553

肝素药典条款修订提高药物安全性但可能给用药带来影响
Changes to heparin improve drug safety but may impact dosing

2009-10-10

724

FDA发布关于铁鳌合剂Exjade安全性的早期沟通信息
FDA issues early communication about safety of iron chelator...

2009-10-10

716

美国FDA警告糖尿病治疗药物Januvia或Janumet可...
Watch for pancreatitis in patients taking diabetes drugs Jan...

2009-10-10

1177

葛兰素史克公司和FDA警告不要雾化吸入依乐韦
GSK and FDA warn against unapproved nebulization of flu drug...

2009-10-15

686

警惕静脉铁剂Dexferrum致过敏反应
Watch for anaphylaxis in patients receiving parenteral iron ...

2009-10-22

476

公司自愿召回一些NSAID酮咯酸瓶装注射剂
Company voluntary recalls some vials of injectable NSAID Ket...

2009-10-23

459

服用肿瘤坏死因子阻断剂Rituxan的类风湿性关节炎患者中又...
Another case of PML occurs in patient with RA who took TNF-b...

2009-10-28

502

糖尿病药物Byetta最新标签强调肾脏疾病风险
Risk for kidney problems highlighted in updated label for di...

2009-11-05

539

由于担心污染，FDA和Hospira召回部分批次的丙泊酚乳剂...
Contamination concern prompts recall of some lots of Hospira...

2009-11-12

464

FDA警告：部分局麻药应避免关节腔内持续输注
Avoid continuous intraarticular infusions of certain local a...

2009-11-18

529

FDA警告Genzyme公司的部分注射剂产品可能受污染
FDA warns of possible contaminants in some injectable Genzym...

2009-11-18

776

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病例分析

甲状腺功能亢进合并黄疸

王燕燕王曙

上海交通大学附属瑞金医院内分泌科

患者，女，69岁。2009年1月无明显诱因下出现乏力，当时程度较轻，未予以重视。2009年3月患者乏力症状加重，尿色逐渐加深，大便习惯改变，颜色变淡。4月18日入我院感染科治疗，诉轻度头晕、心慌，体重减轻10kg。无肝区疼痛，无发热，无腹痛、腹泻、腹胀、里急后重，无恶性、呕吐等。入院半月前于外院就诊，查肝功能：ALT 601IU/L，AST 785IU/L，TBIL 97.7umol/L，白蛋白 41g/L，甲状腺功能：游离T3 30.6pmol/L，游离T4 51.9pmol/L，心电图示快速房颤。

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