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denosumab在晚期乳腺癌患者中显现5个月的治疗优势
Denosumab Update Shows 5-Month Advantage in Advanced Breast ...

2010-12-15

GSK最终以7, 000万美元收购南京美瑞制药
GSK Finalizes Acquisition Of Nanjing Meirui For $70 Million

2010-12-14

碳酸二羟铝钠咀嚼片(Rolaids)中含有金属颗粒和木质颗粒...
Metal and wood particles found in Rolaids Softchews prompts ...

2010-12-14

曲妥珠单抗/帕妥珠单抗二联疗法可根治某些早期乳腺癌
Trastuzumab/Pertuzumab Doublet Eradicates Some Early Breast ...

2010-12-14

FDA专家小组支持Lap-Band用于肥胖病情较轻的患者
Lap-Band Gains Panel Support For Use In Less Obese, Less Sic...

2010-12-13

EMA加大信息透明度，将公开所有不良反应资料
EMA Prepares for Data-Request Blitz; All Adverse Reaction In...

2010-12-13

FDA专家小组支持批准武田/Orexigen开发的减肥药Co...
FDA Panel Backs Approval Of Takeda/Orexigen's Obesity Drug C...

2010-12-10

FDA在一项法规提案中扩大了可标识心脏保健作用的植物甾醇产品...
FDA Expands Phytosterol Heart Health Claim In Proposed Rule

2010-12-09

抗生素库比星2 min静脉注射剂获准
Antibiotic Cubicin approved for use as a 2-minute IV injecti...

2010-12-08

抗心律失常药胺碘酮的预混静脉注射剂获准
Premixed IV formulation of antiarrhythmic amiodarone approve...

2010-12-08

美国参议院提交食品安全法案供众议院表决
Senate Sends Food Safety Legislation To House For Approval

2010-12-08

市场传闻称GSK可能收购南京美瑞制药以拓展在华泌尿类药物市场
Market Rumors Grow On Potential GSK Purchase Of Nanjing MeiR...

2010-12-08

105

PCORI委员会关注有效利用卫生电子技术与疗效对照研究之间的...
PCORI Board Eyes Connection Between Health IT Meaningful Use...

2010-12-01

194

雇主和医疗改革决定着戒烟发展的前景
Smoking Cessation Growth Opportunities Lay With Employers, H...

2010-11-30

204

中国财政部针对2011年的医疗改革新增了资金投入
New Chinese Finance Ministry Funding For Healthcare Reforms ...

2010-11-30

252

前列腺癌市场概况：并非Provenge独享
Prostate Cancer Market Snapshot: More Than Provenge

2010-11-29

244

FDA批准了腋下应用的新型局部外用睾酮替代药
FDA approves new topical testosterone replacement product fo...

2010-11-26

102

波士顿科技通过收购Sadra进军经导管瓣膜市
Boston Sci Makes Its Play In Transcatheter Valves With Sadra...

2010-11-25

Gablofen鞘内注射液获准用于治疗重度痉挛
Intrathecal Gablofen approved for management of severe spast...

2010-11-25

108

慢性肾脏病患者使用Bardoxolone可增加肾小球滤过率估...
Bardoxolone Boosted eGFR in Chronic Kidney Disease

2010-11-24

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FDA批准生物制剂Stelara用于某些类型银屑病的治疗
FDA approves biologic product Stelara for certain types of p...

2009-10-10

2248

FDA批准治疗高血压的复方制剂Exforge HCT
Triple antihypertensive combo Exforge HCT receives FDA appro...

2009-05-05

1605

复方降压药Tekturna HCT获准作为一线降压药
Combo antihypertensive Tekturna HCT approved as first-line t...

2009-07-24

1515

培美曲塞维持治疗提高肺癌患者的存活率
Pemetrexed Maintenance Improves Lung Cancer Survival

2009-09-22

1461

FDA批准Onglyza用于2型糖尿病
FDA approves Onglyza for type 2 diabetes

2009-08-07

1393

非典型性抗精神病药Fanapt获FDA批准用于治疗精神分裂症
Atypical antipsychotic Fanapt receives FDA approval for trea...

2009-05-08

1358

美国FDA批准不定期药Intuniv用于治疗ADHD
FDA approves nonscheduled Intuniv for ADHD

2009-09-10

1213

卡铂+聚乙二醇脂质体阿霉素治疗复发性卵巢癌等效于卡铂+紫杉醇
Carboplatin/Pegylated Liposomal Doxorubicin as Effective as ...

2009-07-13

1161

新型他汀类药物利维乐获得FDA批准
New statin drug Livalo receives FDA approval

2009-08-06

1119

莫西沙星改善单纯性结核病的三联治疗
Moxifloxacin Improved on Triple Therapy in Uncomplicated Tub...

2009-04-02

1097

FDA批准Byetta注射剂单药治疗2型糖尿病
FDA approves injectable Byetta as monotherapy for type 2 dia...

2009-11-04

1094

FDA授权静脉抗病毒药帕拉米韦用于某些H1N1流感病例的紧急...
FDA grants emergency use authorization to IV antiviral peram...

2009-10-28

1093

勃林格殷格翰公司的心血管药美卡素和Twynsta获FDA批准
Boehringer Ingelheim's cardiovascular drugs Micardis and Twy...

2009-10-23

1076

拜耳如何确保在中国市场的龙头地位：Liam Condon专访
How Bayer Secured The Top-Spot In China: An Interview With L...

2010-03-02

1059

中国卫生部将发布《基本药物临床应用指南》
China's Ministry Of Health To Release Guidance For Doctors O...

2010-02-22

987

Tracleer已获准扩大治疗肺动脉高压的适应证范围
Tracleer now approved for a wider range of patients with pul...

2009-08-17

975

药企炒热OTC市场，FDA加大监管力度：2009年大事盘点
Pharma Firms Stir OTC Market, FDA Hones Enforcement: Top Sto...

2010-01-08

929

每月应用一次的新型抗精神病药注射制剂已获准用于治疗精神分裂症
New once-monthly antipsychotic injection approved for schizo...

2009-08-11

911

速效胰岛素Novolog的最新说明书允许在胰岛素泵内的储存时...
Updated label for fast-acting insulin Novolog allows for lon...

2009-07-23

903

FDA已批准2009/2010年的季节性流感疫苗
FDA approves flu vaccine for 2009/2010 season

2009-07-23

899

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[栏目介绍]

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时间

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美国FDA批准不定期药Intuniv用于治疗ADHD
FDA approves nonscheduled Intuniv for ADHD

2009-09-10

1213

诺和诺德GLP-1类似物Victoza赢得开门红
Novo Nordisk's GLP-1 Victoza Off To A Good Start

2010-04-29

730

眼内注射Lucentis获准用于治疗黄斑水肿
Intraocular injection Lucentis approved for new macular edem...

2010-06-28

590

莫西沙星改善单纯性结核病的三联治疗
Moxifloxacin Improved on Triple Therapy in Uncomplicated Tub...

2009-04-02

1097

PARP抑制剂可使乳腺癌生存延长近5个月
PARP Inhibitor Adds Nearly 5 Months to Breast Cancer Surviva...

2010-10-15

220

卡铂+聚乙二醇脂质体阿霉素治疗复发性卵巢癌等效于卡铂+紫杉醇
Carboplatin/Pegylated Liposomal Doxorubicin as Effective as ...

2009-07-13

1161

中国医改能给创新药带来更高的回报吗？
Will China Healthcare Reform Drive Higher Rewards For Innova...

2010-11-23

152

波士顿科技通过收购Sadra进军经导管瓣膜市
Boston Sci Makes Its Play In Transcatheter Valves With Sadra...

2010-11-25

Gablofen鞘内注射液获准用于治疗重度痉挛
Intrathecal Gablofen approved for management of severe spast...

2010-11-25

108

FDA批准了腋下应用的新型局部外用睾酮替代药
FDA approves new topical testosterone replacement product fo...

2010-11-26

102

前列腺癌市场概况：并非Provenge独享
Prostate Cancer Market Snapshot: More Than Provenge

2010-11-29

244

雇主和医疗改革决定着戒烟发展的前景
Smoking Cessation Growth Opportunities Lay With Employers, H...

2010-11-30

204

中国财政部针对2011年的医疗改革新增了资金投入
New Chinese Finance Ministry Funding For Healthcare Reforms ...

2010-11-30

252

PCORI委员会关注有效利用卫生电子技术与疗效对照研究之间的...
PCORI Board Eyes Connection Between Health IT Meaningful Use...

2010-12-01

194

EMA批准氯吡格雷的新适应证
EMA Okays New Indications for Clopidogrel

2010-11-23

慢性肾脏病患者使用Bardoxolone可增加肾小球滤过率估...
Bardoxolone Boosted eGFR in Chronic Kidney Disease

2010-11-24

EMA加大信息透明度，将公开所有不良反应资料
EMA Prepares for Data-Request Blitz; All Adverse Reaction In...

2010-12-13

抗生素库比星2 min静脉注射剂获准
Antibiotic Cubicin approved for use as a 2-minute IV injecti...

2010-12-08

抗心律失常药胺碘酮的预混静脉注射剂获准
Premixed IV formulation of antiarrhythmic amiodarone approve...

2010-12-08

美国参议院提交食品安全法案供众议院表决
Senate Sends Food Safety Legislation To House For Approval

2010-12-08

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病例分析

甲状腺功能亢进合并黄疸

王燕燕王曙

上海交通大学附属瑞金医院内分泌科

患者，女，69岁。2009年1月无明显诱因下出现乏力，当时程度较轻，未予以重视。2009年3月患者乏力症状加重，尿色逐渐加深，大便习惯改变，颜色变淡。4月18日入我院感染科治疗，诉轻度头晕、心慌，体重减轻10kg。无肝区疼痛，无发热，无腹痛、腹泻、腹胀、里急后重，无恶性、呕吐等。入院半月前于外院就诊，查肝功能：ALT 601IU/L，AST 785IU/L，TBIL 97.7umol/L，白蛋白 41g/L，甲状腺功能：游离T3 30.6pmol/L，游离T4 51.9pmol/L，心电图示快速房颤。

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